Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-03-07Clinical Trial Update: Safety And Efficacy Of Rifabutin In Patients For Non-HIV Patients
Clinical trial update on safety and efficacy of rifabutin in non-HIV patients, completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection [Phase 3]
Completed Phase 3 open-label study comparing dolutegravir and efavirenz for HIV/TB co-infection; results posted in 2019.
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Real-time Tuberculosis Medication Adherence Intervention in Rural Southwestern Uganda [NA]
An update on a real-time tuberculosis medication adherence intervention trial conducted in rural southwestern Uganda.
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CLINICAL_TRIALS research · 2019-02-04Clinical Trial Update: Pharmacokinetic and Therapeutic Adaptation of Linezolid in the Treatment of Multi-Resistant Tuberculosis [NA]
Completed clinical trial evaluating pharmacokinetics and dosing strategies of Linezolid for treatment of multi-drug resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: A Cluster-Randomized Trial of DOTS vs DOTS Plus Active Case Finding
This cluster-randomized trial comparing DOTS to DOTS Plus active case finding for tuberculosis has completed. The snippet does not report tr…
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FDA approval · 2019-01-23FDA Approved: RIFADIN IV — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application for Rifadin IV (rifampin) from Sanofi-Aventis U.S. LLC, updating the labeling to include the intrave…
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CLINICAL_TRIALS research · 2019-01-17Clinical Trial Update: Innovative Reagents for Improving Rapid Diagnosis of Mycobacterial Infections
A clinical trial update from St George's, University of London describes work on innovative reagents to improve rapid diagnosis of mycobacte…
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CLINICAL_TRIALS trial_result · 2019-01-10Clinical Trial Update: TB Host Directed Therapy [Phase 2]
Phase 2 clinical trial update for a host-directed therapy targeting tuberculosis.
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CLINICAL_TRIALS trial_result · 2018-12-31Clinical Trial Update: Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis [Phase 3]
Phase 3 trial comparing raltegravir to efavirenz in ART-naive HIV-1 patients on rifampin for active tuberculosis; completed status ongoing r…
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CLINICAL_TRIALS trial_result · 2018-12-24Clinical Trial Update: The Correlate of Risk Targeted Intervention Study [Phase 2, Phase 3]
A trial update for a Phase 2/Phase 3 study on a targeted intervention for tuberculosis, with status currently unknown.
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB) [Phase 3]
Phase 3 clinical trial BRIEF TB evaluating rifapentine-isoniazid for tuberculosis prevention has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Healthy Infants [Phase 2]
Phase 2 safety and immunogenicity study of a tuberculosis vaccine candidate in healthy infants completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women [Phase 4]
Phase 4 trial comparing immediate versus deferred isoniazid preventive therapy in HIV-infected pregnant women; study completed with results …
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FDA approval · 2018-11-08FDA Approved: CYCLOSERINE — Supplemental Application (Dr. Reddys Laboratories, Inc.)
FDA approved a supplemental application for cycloserine from Dr. Reddy's Laboratories, Inc. (ANDA 060593).
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Phase 2a EBA Trial of AZD5847 [Phase 2]
Phase 2a trial update for AZD5847 in tuberculosis completed.
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: PK Study of Rifampicin Interactions With DMPA and Efavirenz in TB [Phase 2]
Phase 2 trial updating pharmacokinetics of rifampicin interactions with Depo-Provera (DMPA) and efavirenz in HIV and TB patients; completed …
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive Adults [Phase 2]
Phase 2 safety and immunogenicity trial of a tuberculosis vaccine candidate in HIV-positive adults completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults [Phase 4]
Phase 4 trial evaluating how HIV infection and active tuberculosis affect immune responses to the trivalent influenza vaccine in adults.
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Safety and Immunogenicity of 2 Formulations of Tuberculosis Vaccine GSK692342 Given at 0,1 Months to Healthy Adults [Phase 2]
Phase 2 trial assessing safety and immunogenicity of two formulations of the TB vaccine GSK692342 in healthy adults.
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CLINICAL_TRIALS research · 2018-07-31Clinical Trial Update: Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph Nodes [NA]
A clinical trial evaluating endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for diagnosing tuberculosis in medi…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics and ex-vivo antitubercular activity of the PBTZ169 formulation has completed…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis [Phase 3]
Phase III trial evaluating Vaccae™ for prevention of tuberculosis has completed; the update does not include specific efficacy or safety res…
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India
Completed trial assessing dietary intake and the prevalence of refeeding syndrome among high-risk tuberculosis patients in Chhattisgarh, Ind…
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: Strategic Screening for Infectious Diseases (Tuberculosis, HIV, HBV, HCV) Amongst Migrants in France
This clinical trial update describes a strategic screening initiative for HIV, Hepatitis B, Hepatitis C, and Tuberculosis among migrants in …
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing MTBVAC to BCG in newborns with a safety arm in adults to evaluate safety and immunogenicity for tubercu…