Tuberculosis Pulmonary
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB [Phase 2]
A Phase 2 global multicenter platform trial by University College London evaluating different regimens and treatment durations for pulmonary…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Linezolid Dosing Strategies in Drug-Resistant TB [Phase 2]
A Phase 2 clinical trial is evaluating linezolid dosing strategies for drug-resistant tuberculosis. The study is currently listed as ACTIVE_…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) [Phase 2, Phase 3]
This document reports an update on a pragmatic Phase 2/3 trial evaluating a more effective, concise, and less toxic regimen for multidrug-re…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Performance of Xpert MTB/RIF and XDR Assay for Diagnosis of Pulmonary Tuberculosis and Resistant Pulmonary TB
This clinical trial protocol assesses the diagnostic performance of the Xpert MTB/RIF assay and an XDR assay for pulmonary tuberculosis and …
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Optimizing(O) RIfapentine-based(RI) Regimen and shortENing(EN) the Treatment of Drug-sensitive Tuberculosis(T) [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial investigating a rifapentine-based regimen to shorten treatment for drug-susceptible pulmonary tuberculosis,…
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) [Phase 2, Phase 3]
A clinical trial investigated atorvastatin as a treatment adjunct for pulmonary tuberculosis in Nigeria, spanning Phase 2 and Phase 3 and no…
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis [Phase 2, Phase 3]
Phase 2/3 trial evaluating two-month regimens with novel drug combinations to improve effectiveness against drug-sensitive pulmonary tubercu…
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment [Phase 3]
Phase 3 trial update evaluating sitafloxacin-containing regimens to shorten tuberculosis treatment in pulmonary tuberculosis; not yet recrui…
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: Efficacy of Metformin for Sputum Conversion in Patients With Active Pulmonary Tuberculosis [Phase 1, Phase 2]
A clinical trial update evaluates the efficacy of metformin for sputum conversion in patients with active pulmonary tuberculosis (Phase 1/Ph…
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2 [Phase 4]
Phase 4 clinical trial update for a new IL-2–based treatment for primary smear-positive pulmonary tuberculosis.
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CLINICAL_TRIALS withdrawal · 2020-01-21Clinical Trial Update: Novel Triple-dose Tuberculosis Retreatment Regimens: How to Overcome Resistance Without Creating More [Phase 3]
Phase 3 trial on triple-dose tuberculosis retreatment regimens was withdrawn.
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CLINICAL_TRIALS research · 2019-01-29Clinical Trial Update: Respiratory Function in Patients With Post-tuberculosis Lung Impairment [NA]
A clinical trial update regarding respiratory function in patients with post-tuberculosis lung impairment; no results or status details are …
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design [Phase 2]
Phase 2 clinical trial evaluating SQ109, high-dose Rifampicin, and Moxifloxacin in adults with smear-positive pulmonary tuberculosis using a…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Safety and Efficacy of Blocking IL-4 With Pascolizumab in Patients Receiving Standard Therapy for Pulmonary Tuberculosis [Phase 2]
This Phase 2 trial is evaluating the safety and efficacy of blocking IL-4 with Pascolizumab in patients receiving standard therapy for pulmo…
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CLINICAL_TRIALS research · 2017-03-20Clinical Trial Update: Shortened Regimens for Drug-susceptible Pulmonary Tuberculosis [Phase 4]
A Phase 4 study from Beijing Chest Hospital is evaluating shortened regimens for drug-susceptible pulmonary tuberculosis, with the trial sta…
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CLINICAL_TRIALS research · 2016-11-18Clinical Trial Update: Evaluation of PET/MRI Using a Somatostatin Analog Tracer as a Novel Approach to Detecting Pathology in High Risk TB-exposed Contacts [Phase 1]
Phase 1 clinical trial evaluating PET/MRI using a somatostatin analog tracer as a novel approach to detect pathology in high-risk TB-exposed…
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CLINICAL_TRIALS research · 2012-02-02Clinical Trial Update: Feasibility of a Lateral Flow Urine Lipoarabinomannan (LAM) Test for Diagnosis of Tuberculosis [NA]
The ClinicalTrials.gov update describes a feasibility study of a lateral flow urine lipoarabinomannan (LAM) test for diagnosing tuberculosis…
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CLINICAL_TRIALS trial_result · 2009-03-04Clinical Trial Update: MDR TB, Levofloxacin, Multi-Drug-Resistant Pulmonary Tuberculosis [Phase 4]
Sanofi-sponsored Phase 4 trial evaluating levofloxacin for pulmonary multidrug-resistant tuberculosis has completed.