Tuberculosis Multidrug-resistant
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents With Pulmonary MDR-TB [Phase 2]
Phase 2 pharmacokinetic study evaluating bedaquiline (TMC207) in combination with a background MDR-TB regimen for treating children/adolesce…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Linezolid Dosing Strategies in Drug-Resistant TB [Phase 2]
A Phase 2 clinical trial is evaluating linezolid dosing strategies for drug-resistant tuberculosis. The study is currently listed as ACTIVE_…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Molecular Epidemiology, Strains Genotyping of Multi-drug Resistant Tuberculosis Circulating in Central Africa Region
A clinical trial in Central Africa is examining the molecular epidemiology and genotyping of circulating multi-drug resistant tuberculosis s…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) [Phase 3]
Phase 3 endTB-Q trial evaluating regimens with newly approved drugs for multidrug-resistant tuberculosis with fluoroquinolone resistance has…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: The Safety and Efficacy of BDL(Bedaquiline Plus Delamanid Plus Linezolid) Regimen in Subjects With Pulmonary Infection of Multi-drug Resistant Tuberculosis (MDR-TB) or Rifampicin-Resistant Tuberculosis (RR-TB) [Phase 4]
Phase 4 clinical trial assessing the safety and efficacy of a bedaquiline-delamanid-linezolid regimen in pulmonary MDR-TB and rifampicin-res…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) [Phase 2, Phase 3]
This document reports an update on a pragmatic Phase 2/3 trial evaluating a more effective, concise, and less toxic regimen for multidrug-re…
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: The Individualized M(X) Drug-resistant TB Treatment Strategy Study [Phase 4]
Phase 4 trial update for an individualized M(X) drug-resistant TB treatment strategy; the study is terminated.
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of levofloxacin for treating multidrug-resistant tuberculosis has completed with p…
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Preventing Acquired Resistance: Strengthen TB Treatment by Adding Amikacin in the First Treatment Week of Multidrug-resistant Tuberculosis [Phase 2]
Phase 2 trial updating TB treatment by adding amikacin during the first treatment week to prevent acquired resistance in multidrug-resistant…
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CLINICAL_TRIALS trial_result · 2023-01-18Clinical Trial Update: A Study of an Oral Short-course Regimen Including Bedaquiline for the Treatment of Participants With Multidrug-resistant Tuberculosis in China [Phase 4]
A Phase 4 trial update evaluating an oral short-course regimen that includes bedaquiline for multidrug-resistant tuberculosis in China.
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB) [Phase 2]
Phase 2 trial update for OPC 67683 in pulmonary sputum culture-positive, multidrug-resistant tuberculosis (TB) has completed with results po…
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CLINICAL_TRIALS withdrawal · 2017-09-11Clinical Trial Update: Efficacy and Tolerability of Delamanid, Linezolid, Pyrazinamide and Levofloxacin [Phase 3]
Phase 3 trial evaluating a four-drug regimen (delamanid, linezolid, pyrazinamide, levofloxacin) for multidrug-resistant tuberculosis has bee…