Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-09-13Clinical Trial Update: Abraxane With or Without Tigatuzumab in Patients With Metastatic, Triple Negative Breast Cancer [Phase 2]
A completed Phase 2 trial evaluating Abraxane with or without Tigatuzumab in metastatic triple-negative breast cancer. Results have been pos…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Study of Erlotinib and Metformin in Triple Negative Breast Cancer [Phase 1]
A Phase 1 trial evaluating the combination of Erlotinib and Metformin in triple-negative breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer [Phase 1]
Phase 1 trial evaluating the combination of veliparib with cisplatin and vinorelbine ditartrate in patients with recurrent and/or metastatic…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Efficacy and Safety of Cabazitaxel Versus Weekly Paclitaxel as Neo-adjuvant Treatment in Patients With Triple Negative or Luminal B/HER2 Normal BC (GENEVIEVE) [Phase 2]
Phase 2 GENEVIEVE trial comparing cabazitaxel to weekly paclitaxel as neoadjuvant therapy in specific breast cancer subtypes to assess effic…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer [Phase 2]
Phase 2 trial of MK-2206 in breast cancer was terminated, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: GDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastatic Breast Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial of GDC-0941 (pictilisib) with cisplatin for androgen receptor-negative triple-negative metastatic breast cancer w…
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CLINICAL_TRIALS withdrawal · 2017-06-27Clinical Trial Update: Study of Immunochemotherapy +/- Hypofractionated Radiation for Complete Response in Solid Tumors [NA]
A clinical trial evaluating immunochemotherapy with optional hypofractionated radiation for complete response in solid tumors has been withd…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Phase 2 Study - Aurora + Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced + Metastatic TNBC [Phase 2]
Phase 2 study of ENMD-2076, an Aurora and angiogenic kinase inhibitor, in previously treated locally advanced or metastatic triple-negative …
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response [Phase 2]
This update reports Phase 2 results from a trial of platinum-based chemotherapy in triple-negative metastatic breast cancer and evaluates p6…
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Metastatic Triple Negative Breast Cancer [Phase 1]
Phase 1 study evaluating stereotactic body radiation therapy combined with an anti-PD-1 antibody in metastatic triple-negative breast cancer…
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CLINICAL_TRIALS withdrawal · 2017-04-24Clinical Trial Update: Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction [Phase 1]
A Phase 1 clinical trial of talazoparib in patients with advanced or metastatic solid tumors unsuitable for surgery and with liver or kidney…
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CLINICAL_TRIALS research · 2017-04-19Clinical Trial Update: Comparative Study on Two Post-operative Adjuvant Chemotherapy Regimens for Treating Triple-negative Breast Cancer [Phase 3]
This document outlines a Phase 3 clinical trial comparing two postoperative adjuvant chemotherapy regimens for triple-negative breast cancer…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: A Randomized Trial of Ixempra Versus Taxol in Adjuvant Therapy of Triple Negative Breast Cancer [Phase 3]
Phase 3 randomized trial comparing ixabepilone (Ixempra) with paclitaxel (Taxol) as adjuvant therapy for triple-negative breast cancer has c…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced, Metastatic, or Recurrent Triple Negative Invasive Breast Cancer [Phase 2]
Phase 2 trial of RO4929097, a gamma-secretase/Notch pathway inhibitor, in advanced/metastatic/recurrent triple-negative breast cancer was te…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Phase 2 Trial of Selinexor (KPT-330) for Metastatic Triple Negative Breast Cancer (TNBC) [Phase 2]
Phase 2 trial of selinexor (KPT-330) in metastatic triple-negative breast cancer has completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Two Regimens of SAR240550/Weekly Paclitaxel and Paclitaxel Alone as Neoadjuvant Therapy in Triple Negative Breast Cancer Patients [Phase 2]
A Phase 2 neoadjuvant trial in triple-negative breast cancer compares regimens of SAR240550 with weekly paclitaxel versus paclitaxel alone.
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Brostallicin and Cisplatin in Treating Patients With Metastatic Breast Cancer [Phase 2]
A Phase 2 trial evaluating brostallicin with cisplatin in metastatic triple-negative breast cancer has completed, with results posted in 201…
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CLINICAL_TRIALS withdrawal · 2017-03-09Clinical Trial Update: A Study of Neoadjuvant Paclitaxel in Combination With Bavituximab in Early- Stage Triple- Negative Breast Cancer [Phase 2]
A Phase 2 trial evaluating neoadjuvant paclitaxel in combination with bavituximab for early-stage triple-negative breast cancer has been wit…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Study Evaluating the Safety and Efficacy of Onartuzumab And/or Bevacizumab in Combination With Paclitaxel in Participants With Metastatic, Triple Negative Breast Cancer [Phase 2]
Phase 2 study evaluating the safety and efficacy of Onartuzumab and/or Bevacizumab in combination with Paclitaxel for metastatic triple-nega…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Erlotinib Plus Chemotherapy for Treatment of Triple Negative Breast Cancer [Phase 2]
This clinical trial update covers a Phase 2 study of erlotinib in combination with chemotherapy for triple-negative breast cancer. The curre…
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CLINICAL_TRIALS withdrawal · 2016-12-07Clinical Trial Update: A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients [Phase 1, Phase 2]
This Phase 1/Phase 2 trial evaluating CDX-1401 in combination with Poly-ICLC and pembrolizumab for previously treated advanced solid tumors …
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CLINICAL_TRIALS research · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 trial evaluating CAR-pNK cell immunotherapy for MUC1-positive relapsed or refractory solid tumors; current status is not provide…
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CLINICAL_TRIALS research · 2016-12-05Clinical Trial Update: Phase I/II Study of Anti-Mucin1 (MUC1) CAR T Cells for Patients With MUC1+ Advanced Refractory Solid Tumor [Phase 1, Phase 2]
Phase 1/2 trial evaluating Anti-Mucin1 (MUC1) CAR T cells in patients with MUC1-positive advanced refractory solid tumors across several can…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Neoadjuvant Treatment of Docetaxel, Anthracycline and Cyclophosphamide (TAC) Versus Docetaxel and Cyclophosphamide (TC) in Triple-Negative or Her2 Positive Breast Cancer [Phase 3]
Phase 3 neoadjuvant trial comparing TAC (docetaxel, doxorubicin, cyclophosphamide) versus TC (docetaxel and cyclophosphamide) in triple-nega…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Neoadjuvant Platinum-based Chemoradiation Therapy for Locally Advanced Triple Negative Breast Cancer [Phase 2]
A Phase 2 neoadjuvant trial of platinum-based chemoradiation for locally advanced triple-negative breast cancer was terminated, with results…