Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Safety and Efficacy of SCT200 in Patients With Relapsed or Metastatic Triple Receptor Negative Breast Cancer [Phase 2]
Phase 2 clinical trial update evaluating SCT200 for safety and efficacy in relapsed or metastatic triple receptor negative breast cancer.
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: A Dose-Finding Study of Birabresib (MK-8628), a Small Molecule Inhibitor of the Bromodomain and Extra-Terminal (BET) Proteins, in Adults With Selected Advanced Solid Tumors (MK-8628-003) [Phase 1]
Phase 1 dose-finding study of birabresib (MK-8628), a BET inhibitor, completed with results posted in 2018 for selected advanced solid tumor…
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CLINICAL_TRIALS trial_result · 2018-09-20Clinical Trial Update: A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer [Phase 2]
Phase 2 trial evaluating ipatasertib in combination with paclitaxel as neoadjuvant treatment for early-stage triple-negative breast cancer h…
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CLINICAL_TRIALS trial_result · 2018-08-29Clinical Trial Update: This Study Was a Prospective, One-arm Open Phase II Clinical Trial. A Systematic Review of the pCR of Apatinib in Combination With the Albumin Paclitaxel and Carboplatin Regimens for the Neoadjuvant Therapy of Triple-negative Breast Cancer, as Well as the Safety of Treatment [Phase 2]
A prospective, one-arm Phase II trial evaluating apatinib in combination with albumin-bound paclitaxel and carboplatin for neoadjuvant thera…
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Eribulin Versus Vinorelbine in Subjects With Locally Recurrent or Metastatic Breast Cancer Previously Treated With Anthracyclines and Taxanes [Phase 3]
Phase 3 trial comparing eribulin to vinorelbine in locally recurrent or metastatic breast cancer after anthracycline and taxane treatment ha…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast Cancer [Phase 2]
Phase 2 study assessing the safety and efficacy of enzalutamide in patients with advanced, androgen receptor-positive triple-negative breast…
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: MUC1 Vaccine for Triple-negative Breast Cancer [EARLY_Phase 1]
An early-phase Phase 1 trial evaluating a MUC1 vaccine for breast cancer has completed its evaluation. The study targets inflammatory breast…
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CLINICAL_TRIALS withdrawal · 2018-07-18Clinical Trial Update: Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating Glembatumumab Vedotin in combination with nivolumab and ipilimumab for advanced, unresectable solid tu…
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CLINICAL_TRIALS withdrawal · 2018-07-05Clinical Trial Update: Mirvetuximab Soravtansine (IMG853) in Folate Receptor Alpha-expressing TNBC [Phase 1]
Phase 1 trial of Mirvetuximab Soravtansine (IMG853) in folate receptor alpha-expressing triple-negative breast cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy [Phase 1]
This Phase 1 study of veliparib in patients with malignant solid tumors that did not respond to prior therapy has completed.
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CLINICAL_TRIALS research · 2018-05-31Clinical Trial Update: Triple-negative Breast Cancer: a New Perspective on Biomarkers
A completed clinical trial in Brazil assessing biomarkers in triple-negative breast cancer, presenting new perspectives on biomarker roles.
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CLINICAL_TRIALS other · 2018-05-21Clinical Trial Update: Individual Patient Expanded Access-Glembatumumab Vedotin
Expanded access program for glembatumumab vedotin in metastatic gpNMB-expressing triple-negative breast cancer is no longer available.
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: Phase II Pilot Study Assessing Efficacy of a Cisplatin - Metronomic Cyclophosphamide Treatment in Patients With Metastatic Triple Negative Breast Cancer Resistant to Anthracyclines and Taxanes [Phase 2]
Phase II pilot study evaluating cisplatin plus metronomic cyclophosphamide in metastatic triple-negative breast cancer resistant to anthracy…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer [Phase 1]
A Phase 1 study evaluating varlilumab in combination with atezolizumab in patients with advanced cancers has been terminated.
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor [Phase 1]
A Phase 1 trial evaluating the safety and pharmacokinetics of ABBV-221 in adults with advanced solid tumors likely to overexpress EGFR was t…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Dinaciclib and Epirubicin Hydrochloride in Treating Patients With Metastatic Triple-Negative Breast Cancer [Phase 1]
Phase 1 study evaluating the combination of dinaciclib and epirubicin hydrochloride in metastatic triple-negative breast cancer has complete…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: A Study of Bevacizumab With Taxane Therapy in Participants With Triple Negative Breast Cancer [Phase 4]
Phase 4 study evaluating bevacizumab with taxane therapy in triple-negative breast cancer has completed and posted results.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment [Phase 1]
A Phase 1 safety study of the investigational drug MM-151 in patients with advanced solid tumors that have resisted standard treatment has c…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer) [Phase 2, Phase 3]
This clinical trial update reports final results from a Phase 2/3 study evaluating nab-paclitaxel with gemcitabine and carboplatin versus ge…
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CLINICAL_TRIALS trial_result · 2018-03-06Clinical Trial Update: Phase I/II Study of AZD2281 Given in Combination With Paclitaxel in Metastatic Triple Negative Breast Cancer [Phase 1]
This update covers completion of a Phase I/II study of AZD2281 (olaparib) in combination with paclitaxel for metastatic triple-negative brea…
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Carboplatin and Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IIB-IIIC Breast Cancer [Phase 2]
A phase 2 trial evaluating carboplatin with combination chemotherapy, with or without veliparib, in patients with stage IIB–IIIC breast canc…
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CLINICAL_TRIALS research · 2017-11-28Clinical Trial Update: Clinical Study of Neoadjuvant Therapy With Apatinib and Paclitaxel in Local Advanced Triple-negative Breast Cancer [Phase 2]
Phase 2 study evaluating neoadjuvant Apatinib plus Paclitaxel in local advanced triple-negative breast cancer; status is currently UNKNOWN.
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CLINICAL_TRIALS research · 2017-11-07Clinical Trial Update: Clinical Study on Triple Negative Breast Cancer With Chinese Medicine
An update on a trial for triple-negative breast cancer using Traditional Chinese Medicine, with outcomes listed as progression-free survival…
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Study of Neoadjuvant Treatment of Locally Advanced Breast Cancer With CAP Regimen [Phase 2]
A Phase 2 neoadjuvant trial evaluating the CAP regimen (cyclophosphamide, doxorubicin, paclitaxel) for locally advanced breast cancer, inclu…
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Addition of Vismodegib to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer Patients [Phase 2]
A Phase 2 trial evaluating adding vismodegib to neoadjuvant chemotherapy in triple-negative breast cancer patients; the trial status is unkn…