Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer [Phase 1, Phase 2]
A Phase 1/2 trial assessing TIL Gean Therapy in combination with immunotherapy for advanced or metastatic refractory breast cancer is curren…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours [Phase 1]
This clinical trial update reports the completion of a first-in-human Phase 1 study evaluating AZD8701 with or without durvalumab in adults …
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: PARPi or Capecitabine Combined With PD-1 Inhibitors as Adjuvant Therapy in High-risk TNBC [Phase 3]
This clinical trial update describes an ongoing Phase 3 study evaluating PARP inhibitor or capecitabine in combination with PD-1 inhibitors …
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer [Phase 1]
Phase 1 study assessing safety and preliminary efficacy of ipatasertib plus atezolizumab with paclitaxel or nab-paclitaxel in locally advanc…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers [Phase 1]
This document reports a Phase 1 clinical trial of NI-1801 for mesothelin-expressing solid cancers, with recruiting status and multiple indic…
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CLINICAL_TRIALS withdrawal · 2024-10-24Clinical Trial Update: Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast Cancer [Phase 2]
Phase 2 trial of panitumumab and pembrolizumab in combination with neoadjuvant chemotherapy for stage III-IV triple-negative breast cancer h…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors. [Phase 1, Phase 2]
Clinical trial update reporting safety, pharmacokinetics, and efficacy findings for tinostamustine in patients with advanced solid tumors, i…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Cellular Immune Responses in Triple-negative Breast Cancer - High Throughput Immunogenetic Studies
A clinical trial exploring cellular immune responses in triple-negative breast cancer using high-throughput immunogenetic studies is current…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Atezolizumab Combined With Immunogenic Chemotherapy in Patients With Metastatic Triple-negative Breast Cancer [Phase 2]
A phase 2 study evaluating atezolizumab in combination with immunogenic chemotherapy for metastatic triple-negative breast cancer has comple…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial of JK08 for unresectable locally advanced or metastatic cancer conducted by Salubris Biotherapeutics is cur…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer [Phase 1]
Phase 1 trial evaluating the combination of alpelisib and enzalutamide in androgen receptor and PTEN positive metastatic breast cancer has c…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: PhI to Solid Tumors and PhII to Locally Advanced or mTNBC [Phase 1]
Laekna Limited reports a Phase 1 trial in solid tumors and a Phase 2 trial in locally advanced or metastatic triple-negative breast cancer; …
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Window of Opportunity Trial, PARP Inhibitor Rucaparib Affect on PD-L1 Expression in Triple Negative Breast Tumors [EARLY_Phase 1]
An early-phase window-of-opportunity trial assessed whether the PARP inhibitor rucaparib modulates PD-L1 expression in triple-negative breas…
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: The Role of Simvastatin in the Epithelial-Mesenchymal Transition Process of Breast Cancer [Phase 2]
A Phase 2 clinical trial is investigating simvastatin's effect on the epithelial-mesenchymal transition in triple-negative breast cancer. Re…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant Chemotherapy [Phase 2]
Phase 2 trial update on atorvastatin in patients with stage IIb-III triple-negative breast cancer who did not achieve pathologic complete re…
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: Comparison of TP and TAC Regimens in Neoadjuvant Treatment of TNBC [Phase 2]
A Phase 2 neoadjuvant trial comparing TP and TAC regimens in triple-negative breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating enzalutamide plus paclitaxel in stage I-III androgen receptor-positive triple-negative breast cancer ha…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations [Phase 2]
Phase 2 trial of PARP inhibition in triple-negative breast cancer with BRCA1/2 mutations completed; results have been posted.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC [Phase 2]
A single-arm, prospective Phase II trial assessing Utidelone plus capecitabine for active brain metastases in triple-negative metastatic bre…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Apatinib Combined with Albumin-Bound Paclitaxel for Treatment of Advanced Triple Negative Breast Cancer [Phase 1, Phase 2]
Apatinib combined with Nab-paclitaxel (albumin-bound paclitaxel) is being studied in Phase 1/2 for advanced triple-negative breast cancer an…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 Trial [Phase 2]
A Phase 2 clinical trial update for TONIC-3 evaluating novel immunotherapy strategies in advanced/metastatic triple-negative breast cancer; …
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: JK-1201I in Triple Negative Breast Cancer Patients with Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating JK-1201I in patients with triple-negative breast cancer and brain metastases; the study is not yet recru…
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CLINICAL_TRIALS research · 2024-09-04Clinical Trial Update: Asian Multicenter Prospective Study of ctDNA Sequencing
Clinical trial update on an Asian multicenter prospective study evaluating circulating tumor DNA sequencing across multiple cancers, sponsor…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating an omega-3 fatty acid-based anti-cancer therapy in patients with metastatic triple-negative inflammato…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Sitravatinib in Metastatic Breast Cancer [Phase 2]
Phase 2 trial of sitravatinib in metastatic breast cancer, including triple-negative breast cancer, was terminated with results posted in 20…