Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: CtDNA Based MRD Testing for NAC Monitoring in TNBC
This clinical trial update describes a study evaluating ctDNA-based minimal residual disease testing to monitor neoadjuvant chemotherapy in …
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Omission of SLNB in Triple-negative and HER2-positive Breast Cancer Patients with RCR and PCR in the Breast After NAST [NA]
Clinical trial update on omitting sentinel lymph node biopsy in patients with triple-negative and HER2-positive breast cancer after neoadjuv…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Assessment of Complete Pathologic Response After Neoadjuvant Chemotherapy for Breast Cancer
This clinical trial update reports on the assessment of complete pathologic response after neoadjuvant chemotherapy in breast cancer. The st…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors [Phase 1, Phase 2]
An update on the Phase 1/2 study of CYT-0851 in B-cell malignancies and advanced solid tumors, noting completion of Phase 1/2 cohorts.
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: A Phase II Clinical Study to Evaluate the Safety, Pharmacokinetic Profile, and Preliminary Efficacy of IMM2510 in Combination with Chemotherapy As First-line Treatment in Subjects with Non-small Cell Lung Cancer or Triple-negative Breast Cancer [Phase 2]
Phase II clinical study to evaluate safety, pharmacokinetics, and preliminary efficacy of IMM2510 in combination with chemotherapy as first-…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Paclitaxel + Carboplatin + Durvalumab With or Without Oleclumab for Previously Untreated Locally Recurrent Inoperable or Metastatic TNBC [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating paclitaxel and carboplatin with durvalumab, with or without oleclumab, as first-line therapy for previ…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies. [Phase 1]
A Phase I/Ib trial of NZV930 alone and in combination with PDR001 and/or NIR178 in patients with advanced malignancies has been terminated.
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: All Trans Retinoic Acid Combined with Toripalimab+Chemotherapy for Locally Advanced Inoperable or Metastatic Triple Negative Breast Cancer：a Multi-center, Multi-cohort Phase II Trial [Phase 2]
A Phase II trial investigating the combination of all-trans retinoic acid with toripalimab and chemotherapy for locally advanced inoperable …
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: JAK1 Inhibitor Ivarmacitinib Reversing Immunotherapy Resistance in TNBC [Phase 2]
A Phase 2 clinical trial update reports a JAK1 inhibitor, ivarmacitinib, being studied to overcome immunotherapy resistance in triple-negati…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors [Phase 2]
This clinical trials update describes a multicenter, open-label Phase IIa study to evaluate the efficacy and safety of B1962 injections in a…
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CLINICAL_TRIALS withdrawal · 2024-12-09Clinical Trial Update: Pilot Study of Glembatumumab Vedotin Following Doxorubicin and Cytoxan as Neo-adjuvant Therapy in Gp-NMB-expressing High Risk Triple Negative Breast Cancer [EARLY_Phase 1]
An early-phase pilot study of Glembatumumab Vedotin as neoadjuvant therapy for gp-NMB-expressing high-risk triple-negative breast cancer has…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: OXEL: Immune Checkpoint or Capecitabine or Combination Therapy as Adjuvant Therapy for TNBC With Residual Disease [Phase 2]
Phase 2 trial evaluating immune checkpoint inhibitor, capecitabine, or their combination as adjuvant therapy for triple-negative breast canc…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Comparison of Biological Features Between pN0 Triple Negative Breast Tumours With Size < or = 10 mm (pT1a/b) Versus pT1c T2 < or = 30 mm [NA]
Completed clinical trial comparing biological features of small pN0 triple-negative breast cancers (≤10 mm) with larger tumors (pT1c/T2 ≤30 …
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: SBRT, Chemotherapy, and AK104 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC) [Phase 2]
Phase 2 trial evaluating neoadjuvant therapy combining SBRT, chemotherapy, and AK104 for triple-negative breast cancer is currently recruiti…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Tislelizumab Combined with Nab-Paclitaxel for First-Line Treatment of Advanced Triple-Negative Breast Cancer with Bone Metastasis，an Exploratory, Single-Arm, Multicenter Phase II Clinical Study [Phase 2]
An exploratory Phase II trial evaluating tislelizumab plus nab-paclitaxel as first-line treatment for advanced triple-negative breast cancer…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Different Methods of Capecitabine in Patients With Non-PCR After Neoadjuvant Therapy for TNBC
A clinical trial evaluating different capecitabine regimens in patients with triple-negative breast cancer who did not achieve pathological …
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Safety and Efficacy of Durvalumab Combined to Neoadjuvant Chemotherapy in Localized Luminal B HER2(-) and Triple Negative Breast Cancer. [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and efficacy of durvalumab in combination with neoadjuvant chemotherapy for localized Luminal B HER2-negat…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: De-escalation of Neoadjuvant Chemotherapy Regimens With Immunotherapy Among TNBC
A clinical trial is investigating de-escalation of neoadjuvant chemotherapy regimens combined with immunotherapy for triple-negative breast …
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Multiparametric MRI as a Non-Invasive Biomarker of the Tumor Microenviroment
A clinical trial investigating multiparametric MRI as a non-invasive biomarker of the tumor microenvironment in breast cancer has been suspe…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers [Phase 1, Phase 2]
Clinical trial update for Galinpepimut-S in combination with pembrolizumab in selected advanced cancers (Phase 1/2) with completed status an…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Combination of Olaparib and Navitoclax in Women with HGSC and TNBC [Phase 1]
A Phase 1 clinical trial evaluating the combination of olaparib and navitoclax in women with high-grade serous ovarian cancer and triple-neg…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067 [Phase 1, Phase 2]
Phase 1a/Phase 2 study evaluating safety, preliminary efficacy, PK and PD of ST-067 in various cancers; currently recruiting.
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: A Study of BEBT-209 in Combination With Chemotherapy for the Treatment of Advanced Triple-Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial update shows BEBT-209 in combination with chemotherapy for advanced triple-negative breast cancer is currently recr…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Studying the Senescent T Cell Features and Its Relationship with the Chemotherapy Efficacy in Young TNBC
A clinical trial is studying senescent T cell features and their relationship to chemotherapy efficacy in young patients with triple-negativ…