Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer [Phase 1]
A Phase 1 trial of A2-ESO-1 TCR-Engineered T Cells for NY-ESO-1 overexpression positive triple negative breast cancer has been suspended. Th…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Intratumoral N17350 in Advanced Solid Tumors [Phase 1, Phase 2]
Update on the investigational intratumoral therapy N17350 being studied in advanced solid tumors in Phase 1 and Phase 2 trials, sponsored by…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype [Phase 1]
A Phase 1 trial evaluating dose modifications of systemic anti-cancer therapy in individuals with the Duffy null phenotype. The study enroll…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Study of LY4170156 in Participants With Selected Advanced Solid Tumors [Phase 1]
An early-phase study evaluating LY4170156 in selected advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy [Phase 2]
A Phase 2 trial comparing a mono atezolizumab window followed by atezolizumab–cyclophosphamide therapy versus atezolizumab–cyclophosphamide …
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers [Phase 1, Phase 2]
A Phase 1/2 study of OC-001 in locally advanced or metastatic cancers has been terminated according to its clinical trials registry listing.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ctDNA Positive Patients Diagnosed With cT1bN0 and cT1cN0 TNBC
This ClinicalTrials.gov listing provides an update on a study involving ctDNA-positive patients with early-stage triple-negative breast canc…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ZAP-IT: ZN-c3 + Carboplatin + Pembrolizumab in mTNBC [Phase 1, Phase 2]
Phase 1/2 clinical trial of ZN-c3 combined with carboplatin and pembrolizumab for metastatic triple-negative breast cancer, currently listed…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study of Olaparib and Pembrolizumab in People With Triple Negative Breast Cancer (TNBC) or Hormone Receptor-positive HER2-negative Breast Cancer [Phase 2]
Phase 2 trial evaluating the combination of olaparib and pembrolizumab in triple-negative breast cancer and hormone receptor-positive, HER2-…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Assessement of Potential Interest of [68Ga]Ga-PentixaFor PET/CT in Metastatic Triple Negative Breast Cancer Patients [NA]
This clinical trial update describes the assessment of the PET imaging tracer [68Ga]Ga-PentixaFor for potential use in detecting metastatic …
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: A Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors [Phase 1]
Phase 1 study of Felmetatug Vedotin (SGN-B7H4V) in advanced solid tumors was terminated.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC [Phase 2]
This clinical trial update notes a Phase 2 study evaluating MRI-guided neoadjuvant treatment de-escalation in stage II-III triple-negative b…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies
A clinical trial funded by Elephas is exploring a biomarker-based method to predict response to immunotherapy using live tumor biopsies; the…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Phase 1 Study of [225Ac]-FPI-1434 Injection [Phase 1]
A Phase 1 study of [225Ac]-FPI-1434 injection sponsored by Fusion Pharmaceuticals has been terminated.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas [Phase 1]
DR-0202 is being studied in a Phase 1 trial across multiple locally advanced or metastatic carcinomas; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors [Phase 1, Phase 2]
APL-5125 is being studied in a Phase 1/2 trial for adults with advanced solid tumors, with recruitment ongoing across several indications in…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases [NA]
The fREEDOM trial for Resonance for Early Detection Of Breast Cancer Metastases is currently recruiting participants with invasive breast ca…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Single-Arm Phase Ⅱ Study of Fluzoparib Maintenance in Platinum-sensitive Advanced Triple-Negative Breast Cance [Phase 2]
A single-arm Phase II trial evaluating maintenance therapy with Fluzoparib in platinum-sensitive advanced triple-negative breast cancer. The…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer Patients [Phase 2]
Phase 2 clinical trial evaluating atezolizumab in combination with chemotherapy for metastatic triple-negative breast cancer is currently re…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer [NA]
Clinical trial update describing a study on predicting radiotherapy efficacy in triple-negative breast cancer; the trial is currently active…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: A Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer [Phase 2]
A Phase 2 study evaluating PLX038 for locally advanced or metastatic triple-negative breast cancer has been terminated, according to the cli…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Radiological Prediction of Response to Neoadjuvant Chemoimmunotherapy for Triple-negative Breast Cancer [NA]
A clinical trial update describing a study that aims to predict radiological response to neoadjuvant chemoimmunotherapy in patients with tri…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Ribociclib and Bicalutamide in AR+ TNBC [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of ribociclib in combination with bicalutamide for AR-positive triple-negative breast c…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian [Phase 1]
A Phase 1 study investigating AZD2014 (an mTORC1/2 inhibitor) or AZD5363 (an AKT inhibitor) in recurrent endometrial and ovarian cancers, wi…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Imaging Performance Assessment of 89Zi-girentuximab (89Zr-TLX250) PET in Metastatic Triple Negative Breast Cancer [Phase 2]
Phase 2 imaging study assessing the performance of 89Zr-TLX250 PET in metastatic triple-negative breast cancer; results have been posted.