Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer [Phase 3]
A Phase 3 trial comparing SKB264 to investigator's choice chemotherapy in unresectable recurrent or metastatic triple-negative breast cancer…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02) [Phase 3]
Phase 3 trial update comparing datopotamab deruxtecan (Dato-DXd) versus investigator's choice chemotherapy in locally recurrent or metastati…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Multicenter, Phase II Clinical Study of Sacituzumab Tirumotecan (Sac-TMT) in Combination With KL-A167 for Neoadjuvant Treatment of Triple-Negative Breast Cancer [Phase 2]
Phase II multicenter trial evaluating Sacituzumab Tirumotecan in combination with KL-A167 as neoadjuvant therapy for triple-negative breast …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer [Phase 1]
Phase 1 study evaluating a personalized cancer vaccine immunotherapy in combination with a checkpoint inhibitor for triple-negative breast c…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial evaluating docetaxel chemotherapy in combination with pembrolizumab and interleukin-12 gene therapy for triple-nega…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications [Phase 1]
A Phase 1 clinical trial update describes evaluation of BBI-355 (CHK1 inhibitor) in combination with BBI-825 (RNR inhibitor) for tumors with…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC [Phase 2]
Phase II study evaluating the safety and efficacy of a triple combination of Zimberelimab, Domvanalimab, and Sacituzumab Govitecan as first-…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer [NA]
This clinical trial investigates pre-operative stereotactic ablative radiotherapy (SABR) with or without caloric restriction for early-stage…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Omission of Surgery for Triple-negative Breast Cancer in Complete Response After Neoadjuvant Chemo-immunotherapy [NA]
A clinical trial update indicates that surgery may be omitted for patients with triple-negative breast cancer who achieve complete response …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: FDA018-ADC vs Investigator's Choice Chemotherapy to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer [Phase 3]
Phase 3 trial comparing FDA018-ADC against investigator's choice chemotherapy for locally advanced, recurrent, or metastatic triple-negative…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Pilot Study of Veliparib (ABT-888) and Lapatinib (Tykerb) in Patients With Metastatic, Triple Negative Breast Cancer [NA]
This is a completed pilot trial evaluating veliparib in combination with lapatinib in patients with metastatic triple-negative breast cancer…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Sacituzumab Govitecan Plus Bevacizumab in Metastatic TNBC [Phase 2]
A Phase 2 clinical trial is evaluating the combination of sacituzumab govitecan and bevacizumab in metastatic triple-negative breast cancer,…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Early Detection of Triple Negative Breast Cancer Relapse (CUPCAKE) [NA]
The CUPCAKE study is currently recruiting to evaluate early detection of relapse in patients with triple-negative breast cancer.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors. [Phase 1]
A Phase 1 study evaluating DKY709 alone or in combination with PDR001 in patients with advanced solid tumors. The enrolled diseases include …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Study of Antivascular Therapy Combined With Chemotherapy Versus Chemotherapy in Adjuvant Therapy of TNBC-BLIS Patients (BCTOP-T-A03) [Phase 3]
Phase 3 clinical trial evaluating antivascular therapy in combination with chemotherapy versus chemotherapy alone as adjuvant treatment for …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers [Phase 2]
Phase 2 clinical trial evaluating standard-of-care chemotherapy with or without tocilizumab for metastatic breast cancer, including triple-n…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63) [Phase 3]
A Phase 3 randomized trial evaluating sacituzumab govitecan-hziy in combination with pembrolizumab versus physician's choice in triple-negat…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 [Phase 1]
Phase 1 study assessing adverse events and change in disease activity in adults with select advanced solid tumors treated with ABBV-400; the…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Neoadjuvant Chemotherapy Combined With Sintilimab and Bevacizumab for TNBC (NEOTORCH-BREAST07) [Phase 2]
A Phase 2 neoadjuvant trial evaluating the combination of sintilimab and bevacizumab with chemotherapy for triple-negative breast cancer; th…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Neoadjuvant INBRX-106 in Combination With Pembrolizumab for Stage II/III TNBC Patients [Phase 2]
Phase 2 neoadjuvant trial evaluating INBRX-106 with pembrolizumab for stage II/III triple-negative breast cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer [EARLY_Phase 1]
A Phase 1 EARLY study evaluating neoadjuvant therapy plus contrast-enhanced mammography for early-stage breast cancer is currently recruitin…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Development of a Multi-omics Prediction Model for Immunotherapy Response in Triple-Negative Breast Cancer Subtypes
It reports a clinical trial developing a multi-omics model to predict immunotherapy response in triple-negative breast cancer subtypes; the …
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Prospective, Open-label, Single-arm, Exploratory Clinical Trial to Evaluate the Safety and Tolerability of 225Ac-TR2205 Injection in Patients With Triple-negative Breast Cancer. [EARLY_Phase 1]
A Phase 1, open-label, single-arm study assessing the safety and tolerability of 225Ac-TR2205 injection in patients with advanced metastatic…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Neoadjuvant Chemotherapy Combined With Toripalimab for TNBC (NEOTORCH-BREAST02) [Phase 2]
Phase 2 NEOTORCH-BREAST02 trial is evaluating neoadjuvant chemotherapy with toripalimab in triple-negative breast cancer. The study is curre…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Feasibility of a Lifestyle Intervention for Women With Triple-negative Breast Cancer Under Neoadjuvant Immunotherapy [NA]
A clinical trial update describing a feasibility study of a lifestyle intervention for women with triple-negative breast cancer undergoing n…