Traumatic Brain Injury
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CLINICAL_TRIALS trial_result · 2011-11-17Clinical Trial Update: An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits [Phase 4]
This document reports the completion of a Phase 4 extension study evaluating the efficacy and safety of rivastigmine in patients with trauma…
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CLINICAL_TRIALS research · 2011-11-16Clinical Trial Update: Observational Endothelin and Markers of Cellular Apoptosis In CSF Head Injury
Observational study update from Virginia Commonwealth University examining endothelin signaling and markers of cellular apoptosis in cerebro…
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CLINICAL_TRIALS trial_result · 2011-10-28Clinical Trial Update: Magnesium Sulfate For Brain Injury [Phase 3]
A Phase 3 trial evaluating magnesium sulfate for traumatic brain injury has completed.
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CLINICAL_TRIALS trial_result · 2011-10-21Clinical Trial Update: Effect of Exogenous Lactate on Neurocognitive in Brain Trauma [NA]
A completed clinical trial evaluated the effect of exogenous lactate on neurocognitive outcomes in individuals with traumatic brain injury.
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CLINICAL_TRIALS trial_result · 2011-10-06Clinical Trial Update: Effect of Rosuvastatin on Cytokines After Traumatic Brain Injury [Phase 1, Phase 2]
An update on a clinical trial evaluating rosuvastatin's effect on cytokines in traumatic brain injury (Phase 1 and Phase 2). The study statu…
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CLINICAL_TRIALS trial_result · 2011-09-21Clinical Trial Update: A Phase 2a Dose Escalation Study With SLV334 in Patients With Traumatic Brain Injury. [Phase 2]
A Phase 2a dose-escalation trial of SLV334 in patients with traumatic brain injury has been terminated.
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CLINICAL_TRIALS research · 2011-07-28Clinical Trial Update: Influence of Physical Exercise on Cognitive Functioning of Traumatic Brain Injury Patients [NA]
This clinical trial update investigates whether physical exercise improves cognitive functioning in patients with traumatic brain injury. Th…
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CLINICAL_TRIALS research · 2011-07-21Clinical Trial Update: The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure
This clinical trial update examines how explosive blast exposure compares with post-traumatic stress disorder in terms of effects on brain f…
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CLINICAL_TRIALS trial_result · 2011-07-12Clinical Trial Update: Preventive Sodium Lactate and Traumatic Brain Injury [Phase 2, Phase 3]
A clinical trial update indicates Phase 2 and Phase 3 studies evaluating preventive sodium lactate for traumatic brain injury have been comp…
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CLINICAL_TRIALS research · 2011-06-23Clinical Trial Update: Rehabilitation of Children With Multiple Disabilities [Phase 1]
Phase 1 rehabilitation trial for children with multiple disabilities has completed.
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CLINICAL_TRIALS other · 2011-06-21Clinical Trial Update: Intensive Rehabilitation of Patients With Severe Traumatic Brain Injury - Development of a Didactic Model
Status update indicating the clinical trial on intensive rehabilitation for severe traumatic brain injury has completed, including the devel…
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CLINICAL_TRIALS trial_result · 2011-06-01Clinical Trial Update: Study on the Effect of Prostacyclin Compared to Placebo in Traumatic Brain Injury [Phase 1]
A Phase 1 study comparing prostacyclin to placebo in traumatic brain injury has completed.
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CLINICAL_TRIALS research · 2011-05-18Clinical Trial Update: Normothermia Protocol for Traumatic Brain Injury Patients
This entry provides an update on a clinical trial investigating a normothermia protocol for patients with traumatic brain injury.
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CLINICAL_TRIALS trial_result · 2011-05-09Clinical Trial Update: Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI) [Phase 3]
A Phase 3 trial evaluating hypertonic resuscitation after severe traumatic brain injury was terminated; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-04-28Clinical Trial Update: The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate Traumatic Brain Injury (TBI) Patients [Phase 2]
A Phase 2 clinical trial is evaluating whether a single dose of D-Cycloserine improves cognitive outcomes in adults with moderate traumatic …
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CLINICAL_TRIALS trial_result · 2011-04-26Clinical Trial Update: Executive Dysfunction & Suicide: An Exploration Of Risk Factors In Traumatically Brain Injured Veterans
A completed clinical trial examining executive dysfunction and risk factors for suicide among traumatically brain-injured veterans.
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CLINICAL_TRIALS trial_result · 2011-03-24Clinical Trial Update: Neuroendocrine Dysfunction in Traumatic Brain Injury: Correlation With Cognitive Dysfunction and Repair
Update on a terminated clinical trial investigating neuroendocrine dysfunction after traumatic brain injury and its relationship to cognitiv…
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CLINICAL_TRIALS research · 2010-12-24Clinical Trial Update: A TMU/NIH Integrated Research Project Translation of Basic Research to Clinical Diagnosis and Treatment of Mild Traumatic Brain Injury (mTBI)
An integrated Taipei Medical University and NIH research project aims to translate basic traumatic brain injury research into clinical diagn…
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CLINICAL_TRIALS trial_result · 2010-12-08Clinical Trial Update: Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury [Phase 1, Phase 2]
A controlled Phase 1/2 trial of ABELADRUG200 for severe head injury (traumatic brain injury) is reported with the study status currently unk…
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CLINICAL_TRIALS research · 2010-11-11Clinical Trial Update: Safety Study of Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Traumatic Brain Injury: Dosing Tier 1 [Phase 2]
Phase 2 safety trial update for dosing Tier 1 of human chorionic gonadotropin (hCG) and epoetin alfa in traumatic brain injury; current stat…
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CLINICAL_TRIALS trial_result · 2010-11-09Clinical Trial Update: Prognosis Association of Hypocalcemia on Moderate-severe TBI, COHORTE STUDY
Update on the COHORTE study evaluating whether hypocalcemia influences prognosis in moderate-to-severe traumatic brain injury; current study…
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CLINICAL_TRIALS trial_result · 2010-10-28Clinical Trial Update: My Scrivener® - Measuring Effectiveness and Dose Response in Children [Phase 1, Phase 2]
This document reports a completed Phase 1/Phase 2 trial of My Scrivener in children, evaluating effectiveness and dose response. The study e…
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CLINICAL_TRIALS trial_result · 2010-10-21Clinical Trial Update: Brain Trauma Outcomes in Nova Scotia Study [NA]
A completed clinical trial in Nova Scotia studied outcomes after traumatic brain injury.
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CLINICAL_TRIALS trial_result · 2010-10-15Clinical Trial Update: Canadian Computed Tomography (CT) Head Rule Study [Phase 3]
Phase 3 clinical trial update on the Canadian CT Head Rule study for head injury, with the study status shown as completed.
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CLINICAL_TRIALS research · 2010-09-20Clinical Trial Update: IRB-HSR# 14299: The Use of the Intrathoracic Pressure Regulator (ITPR) to Improve Cerebral Perfusion Pressure in Patients With Altered Intracranial Elastance [Phase 2]
Phase 2 clinical trial update evaluating the intrathoracic pressure regulator to improve cerebral perfusion pressure in patients with trauma…