Traumatic Brain Injury
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CLINICAL_TRIALS research · 2012-10-25Clinical Trial Update: Study of Variables Related to the Discontinuation of Mechanical Ventilation in Patients With Head Injury
This is a clinical trial update studying factors related to discontinuing mechanical ventilation in patients with traumatic brain injury. Th…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI) [Phase 2, Phase 3]
An update on a Phase 2/Phase 3 trial evaluating amantadine hydrochloride for severe traumatic brain injury. The trial results were posted in…
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CLINICAL_TRIALS research · 2012-09-07Clinical Trial Update: Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury. [NA]
An update on a clinical trial evaluating divalproex sodium for mood symptoms and alcohol use after traumatic brain injury, with the study st…
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CLINICAL_TRIALS withdrawal · 2012-09-06Clinical Trial Update: Botulinum Toxin and Saliva Management in Tracheotomised Patients [Phase 2]
A Phase 2 clinical trial evaluating botulinum toxin for saliva management in tracheotomised patients with traumatic brain injury has been wi…
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CLINICAL_TRIALS research · 2012-08-16Clinical Trial Update: Hormone Deficiency After Brain Injury During Combat
An update on a clinical trial investigating hormone deficiency following traumatic brain injury, with a focus on hypopituitarism in combat-r…
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CLINICAL_TRIALS trial_result · 2012-08-08Clinical Trial Update: Mannitol vs HS to Treat ICHT After Severe TBI : Comparison on PtiO2 and Microdialysis Values [Phase 3]
A Phase 3 trial comparing mannitol to hypertonic saline for treating intracranial hypertension after severe traumatic brain injury was termi…
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CLINICAL_TRIALS trial_result · 2012-08-08Clinical Trial Update: Balance and Mild Traumatic Brain Injury (TBI)
A clinical trial conducted by Oregon Health and Science University focusing on balance in individuals with concussion and traumatic brain in…
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Efficacy of Modified Constraint-induced Movement Therapy in Children With Brain Damage [NA]
This entry reports the completion and efficacy findings of a modified constraint-induced movement therapy trial in children with brain injur…
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial (TOPHR HIT) [Phase 3]
Phase 3 trial TOPHR HIT evaluating prehospital hypertonic resuscitation for traumatic brain injury has completed.
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Hypothermia in Children After Trauma [Phase 3]
Phase 3 clinical trial evaluating therapeutic hypothermia in children after traumatic brain injury has been terminated.
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CLINICAL_TRIALS research · 2012-06-26Clinical Trial Update: Study of Reserves After Traumatic Brain Injury [NA]
A clinical trial update from Sheba Medical Center concerning a study on traumatic brain injury, with the trial status currently unknown.
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Cerebral Hemodynamic Effects of Hypertonic Solutions in Severely Head-Injured Patients
This clinical trial update reports on a terminated study evaluating the cerebral hemodynamic effects of hypertonic solutions in patients wit…
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CLINICAL_TRIALS trial_result · 2012-06-20Clinical Trial Update: Telephone Intervention After Traumatic Brain Injury [NA]
A completed clinical trial evaluated telephone intervention after traumatic brain injury.
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CLINICAL_TRIALS research · 2012-06-14Clinical Trial Update: The Value of the Canadian CT Head Rule and the New Orleans Criteria in Minor Head Trauma
Clinical trial update on the value of the Canadian CT Head Rule and New Orleans Criteria in minor head injury, with the study status listed …
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CLINICAL_TRIALS trial_result · 2012-05-11Clinical Trial Update: Therapeutic Hypothermia for Severe Traumatic Brain Injury in Japan [Phase 3]
Phase 3 clinical trial in Japan evaluating therapeutic hypothermia for severe traumatic brain injury has completed.
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Observational Study of the BrainScope® Ahead™ M-100 in UK Emergency Department Patients With Head Injury
An observational study evaluating the BrainScope Ahead M-100 device in UK emergency department patients with head injury has been terminated…
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CLINICAL_TRIALS research · 2012-04-27Clinical Trial Update: Measurement of Optic Nerve Sheath in Traumatic Raised Intracranial Pressure
This clinical trial update notes a study at McMaster University examining measurement of the optic nerve sheath in patients with traumatic r…
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CLINICAL_TRIALS trial_result · 2012-04-11Clinical Trial Update: Immunemodulation in Patients With Minor Head Injury
The clinical trial evaluating immunomodulation in patients with minor head injury has completed.
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: Is NIRS Able to Detect Ischemia Following Brain Insult
A completed clinical trial evaluating whether near-infrared spectroscopy can detect ischemia after brain insult, including traumatic brain i…
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CLINICAL_TRIALS trial_result · 2012-03-05Clinical Trial Update: Safety of Darbepoetin Alfa Treatment in Patients With Severe Traumatic Brain Injury [Phase 2]
This document reports the completion of a Phase 2 safety evaluation of darbepoetin alfa in patients with severe traumatic brain injury.
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CLINICAL_TRIALS trial_result · 2012-03-02Clinical Trial Update: Anaesthesia With Propofol Versus Midazolam : Effect on Oxidative Stress in the Brain of Head Trauma Patients [Phase 3]
Phase 3 trial comparing propofol versus midazolam for anesthesia in traumatic brain injury patients, assessing oxidative stress in the brain…
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CLINICAL_TRIALS trial_result · 2012-02-16Clinical Trial Update: Platelet Function Analysis in Head Trauma: ASA/Plavix [NA]
The trial update reports completion of a study evaluating platelet function analysis in patients with blunt head trauma treated with aspirin…
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CLINICAL_TRIALS trial_result · 2012-01-24Clinical Trial Update: Single Photon Emission Computed Tomography (SPECT) Imaging Study of Professional American Football Players [NA]
The study, sponsored by Amen Clinics, completed a SPECT imaging trial involving professional American football players with traumatic brain …
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CLINICAL_TRIALS research · 2012-01-18Clinical Trial Update: Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? [Phase 4]
A Phase 4 clinical trial update examines whether discontinuing aspirin after head trauma lowers the incidence of chronic subdural hematoma.
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CLINICAL_TRIALS trial_result · 2011-11-23Clinical Trial Update: Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury and Cognitive Impairment [Phase 3]
Phase 3 trial evaluating rivastigmine for cognitive impairment after traumatic brain injury has completed, reporting efficacy and safety out…