Transitional Cell Carcinoma of the Bladder
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy [NA]
A clinical trial at Thomas Jefferson University is evaluating postoperative outcomes of ureteral stent use versus stent-free radical cystect…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study [Phase 2]
This update describes an open-label, randomized Phase 2 trial evaluating toripalimab with or without sequential intravesical gemcitabine-mit…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Preoperative MPDL3280A in Transitional Cell Carcinoma of the Bladder [Phase 2]
Phase 2 preoperative trial of atezolizumab (MPDL3280A) in transitional cell carcinoma of the bladder has completed.
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: CTC Quantification During TURBT and PKVBT of Transitional Cell Carcinoma in Purging Fluid and Blood [NA]
A clinical trial update describing quantification of circulating tumor cells during TURBT and PKVBT for transitional cell carcinoma of the u…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Neoadjuvant Atezolizumab in Localized Bladder Cancer [Phase 2]
Phase 2 neoadjuvant study of atezolizumab in localized bladder cancer has completed, with results posted on May 31, 2024.
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2, Phase 3]
Phase 2/3 study evaluating rografatinib (BAY1163877) versus chemotherapy in FGFR-positive urothelial carcinoma; the trial is completed with …
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CLINICAL_TRIALS trial_result · 2021-08-20Clinical Trial Update: Biomarkers in Urothelial Cancer Patients Treated With Pembrolizumab [Phase 2]
Phase 2 trial update examining biomarkers in urothelial cancer patients treated with pembrolizumab.
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CLINICAL_TRIALS trial_result · 2021-05-14Clinical Trial Update: PF-03446962 in Relapsed or Refractory Urothelial Cancer [Phase 2]
Phase 2 clinical trial of PF-03446962 in relapsed or refractory urothelial cancer (transitional cell carcinoma of the bladder) has completed…
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CLINICAL_TRIALS trial_result · 2021-04-14Clinical Trial Update: Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer [Phase 2, Phase 3]
Phase 2/3 trial of recombinant adenovirus for non-muscle invasive bladder cancer was terminated.
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CLINICAL_TRIALS trial_result · 2020-10-09Clinical Trial Update: Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney Function [Phase 2]
Phase 2 trial evaluating a combination of gemcitabine, paclitaxel, and doxorubicin in metastatic or unresectable bladder cancer with decreas…
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 open-label dose-finding study evaluated the safety and pharmacokinetics of FPA144 in patients with advanced solid tumors, inclu…
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CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: Sunitinib Malate in Treating Patients With Recurrent Transitional Cell Bladder Cancer [Phase 2]
Phase 2 trial investigating sunitinib malate in recurrent transitional cell bladder cancer has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Surgery [NA]
Terminated trial evaluating broccoli sprout extract in bladder cancer patients undergoing surgery, with results posted in 2016. The study in…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: A Laser Detection for Bladder Cancer by (Photodynamic) Spectra of Urine [Phase 3]
Phase 3 clinical trial update on a laser-based photodynamic detection method for transitional cell carcinoma of the bladder has completed.
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Phase II Trial of Concurrent Administration of Intravesical BCG & Interferon in the Treatment and Prevention of Recurrence of Superficial Transitional Carcinoma of the Urinary Bladder [NA]
This completed Phase II trial evaluated concurrent intravesical Bacillus Calmette-Guérin (BCG) and interferon for treatment and prevention o…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: JAVLOR Association Study in CDDP-unfit Patients With Advanced Transitional Cell Carcinoma: Gemcitabine Versus Carboplatin [Phase 2]
Phase 2 trial comparing gemcitabine versus carboplatin in cisplatin-unfit patients with advanced transitional cell carcinoma of the bladder …
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CLINICAL_TRIALS trial_result · 2015-12-07Clinical Trial Update: First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy [Phase 2, Phase 3]
A completed Phase 2/3 randomized trial in advanced bladder cancer comparing first-line gemcitabine with versus without vinflunine in patient…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Prostate Capsule Sparing Cystectomy and Nerve-sparing Radical Cystoprostatectomy in Men With Bladder Cancer [Phase 2]
A Phase 2 clinical trial evaluated prostate capsule-sparing cystectomy and nerve-sparing radical cystoprostatectomy in men with bladder canc…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: JAVLOR® Online Non-Interventional Trial
The JAVLOR online non-interventional trial sponsored by Pierre Fabre Pharma GmbH has completed.
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Vorinostat in Treating Patients With Locally Recurrent or Metastatic Cancer of the Urothelium [Phase 2]
A Phase 2 trial of Vorinostat for locally recurrent or metastatic urothelial cancers was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: Paclitaxel, Carboplatin and Gemcitabine in the Treatment of Patients With Advanced Transitional Cell Cancer of the Bladder [Phase 2]
This document reports the results of a Phase 2 trial evaluating the combination of paclitaxel, carboplatin, and gemcitabine in patients with…
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CLINICAL_TRIALS research · 2014-03-13Clinical Trial Update: Lymph Node Processing Protocol for Radical Cystectomy and Pelvic Lymph Node Dissection in Bladder Cancer
This completed clinical trial update describes the lymph node processing protocol used during radical cystectomy and pelvic lymph node disse…
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CLINICAL_TRIALS withdrawal · 2014-01-29Clinical Trial Update: Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial Cancer [Phase 2]
This Phase 2 clinical trial evaluating gemcitabine plus cisplatin or a high-dose methotrexate/vinblastine/doxorubicin/cisplatin regimen for …
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CLINICAL_TRIALS trial_result · 2013-08-09Clinical Trial Update: Intravesical Adjuvant Electromotive Mitomycin-C [Phase 2, Phase 3]
Clinical trial update announcing completion of Phase 2/3 evaluation of intravesical adjuvant electromotive delivery of mitomycin-C for bladd…
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Phase II Trial Of PS-341 (Bortezomib) In Patients With Previously Treated Advanced Urothelial Tract Transitional Cell Carcinoma [Phase 2]
This ClinicalTrials.gov entry reports a Phase II study of bortezomib (PS-341) in patients with previously treated advanced urothelial tract …