Records containing: Thrombotic Microangiopathies
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CLINICAL_TRIALS study record update · 2026-03-09An Adaptive Dose Escalation and Expansion Basket Trial to Explore the Safety, Pharmacology, and Clinical Activity of TGD001 in Immune-Mediated Thrombotic Thrombocytopenic Purpura (iTTP) and Other Thrombotic Microangiopathies
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CLINICAL_TRIALS study record update · 2026-02-17Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura: Multicentric Non-inferiority Single-arm Study
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CLINICAL_TRIALS study record update · 2025-12-10A Phase 3 Study to Evaluate the Safety and Efficacy of OMS721 for the Treatment of Atypical Hemolytic Uremic Syndrome (aHUS) in Adults and Adolescents
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CLINICAL_TRIALS study record update · 2025-10-03Auto-immune Thrombotic Thrombocytopenic Purpura : Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center, TWI-LIGHT
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CLINICAL_TRIALS study record update · 2025-10-01Diagnostic and Risk Criteria for Complement Defects in Thrombotic Microangiopathy and Amplifying Conditions, Such as Severe Hypertension: The COMPETE Study.
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CLINICAL_TRIALS study record update · 2025-09-16A Multicenter, Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523, a Syk Inhibitor, in Adult Subjects With Immune Thrombocytopenia
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CLINICAL_TRIALS study record update · 2025-08-06Screening and Identification of Plasma Biomarkers for Early Diagnosis of Transplant-associated Thrombotic Microangiopathy Based on Proteomics and Metabolomics Techniques
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CLINICAL_TRIALS study record update · 2025-07-15TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients
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CLINICAL_TRIALS study record update · 2025-05-15Multicentre Study of Nomacopan (rVA576) in Paediatric Haematopoietic Stem-Cell Transplant Associated Thrombotic Microangiopathy
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CLINICAL_TRIALS study record update · 2025-03-25A Phase 2 Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Narsoplimab in Pediatric Patients (28 Days to ≤ 18 Years of Age.) With High-Risk Hematopoietic Stem Cell Transplant Thrombotic Microangiopathy
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CLINICAL_TRIALS study record update · 2024-12-11Longitudinal Cohort of Thrombosis and Hemostasis Diseases
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CLINICAL_TRIALS study record update · 2024-08-28A Phase 2, Uncontrolled, Three-Stage, Dose-Escalation Cohort Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Clinical Activity of OMS721 in Adults With Thrombotic Microangiopathies
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CLINICAL_TRIALS study record update · 2024-08-07Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy in Patients With High-Risk Neuroblastoma Receiving Tandem Transplants
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CLINICAL_TRIALS study record update · 2023-10-24Retrospective Study of Patients With Thrombotic Microangiopathy Associated With Mitomycin C, Treated or Not With Eculizumab: Clinical Characteristics and and Outcome of These Patients
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CLINICAL_TRIALS study record update · 2023-09-21Early Intervention With Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome (TMA/aHUS)-Associated Multiple Organ Dysfunction Syndrome (MODS) in Hematopoietic Stem Cell Transplant (HCT) Recipients
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CLINICAL_TRIALS study record update · 2023-08-18Automated Surveillance, Alert, and Rapid Diagnosis of Thrombotic Microangiopathies: the ASARD-TMA Study
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CLINICAL_TRIALS study record update · 2023-01-27Multicenter, Uncontrolled Pilot Study Evaluating the Efficacy of Eculizumab in the Treatment of Gemcitabine-induced Thrombotic Microangiopathies
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CLINICAL_TRIALS study record update · 2023-01-04C5 Complement Inhbition Using Ravulizumab for the Treatment of COVID-19 Induced Thrombotic Microangiopathy
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CLINICAL_TRIALS study record update · 2022-12-02Construction of a Database for Thrombotic Microangiopathy
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CLINICAL_TRIALS study record update · 2022-05-12A Retrospective Observational Study of Adult and Pediatric Patients With Thrombotic Microangiopathy (TMA) After Hematopoietic Stem Cell Transplant (HSCT)
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CLINICAL_TRIALS study record update · 2022-02-14A Safety and Efficacy Study of N-acetylcysteine in Patients With Transplant-Associated Thrombotic Microangiopathy
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CLINICAL_TRIALS study record update · 2021-09-16A Pilot Trial of Using Pre-Transplant Risk Stratification and Prophylactic Defibrotide to Prevent Serious Thrombotic Microangiopathy in High-Risk Hematopoietic Stem Cell Transplant Patients
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CLINICAL_TRIALS study record update · 2019-07-25Identification of Early Predictive Factors of Cardiac and Cerebral Involvement in Thrombotic Microangiopathies
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CLINICAL_TRIALS study record update · 2018-09-25A Observational Study to Determine the Prevalence of Pregnancy-related Thrombotic Thrombocytopenic Purpura and Atypical Haemolytic Uraemic Syndrome in Women Affected by Specific Obstetric Complications
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CLINICAL_TRIALS study record update · 2015-02-26Screening of TMA Patients for ADAMTS13 Activity and the Description of Systematic Organ Damage and/or Organ Failure in Different Entities of Thrombotic Microangiopathies (TMA)