Thalassemia Major
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Efficacy Study in Removing Excess Iron From the Heart [Phase 4]
A Phase 4 clinical trial update reports completion of an efficacy study evaluating removal of excess iron from the heart in patients with th…
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FDA approval · 2015-09-09FDA Approved: FERRIPROX — Original Application (Chiesi USA, Inc.)
The FDA granted approval for Ferriprox (deferiprone) to treat iron overload under an original NDA filed by Chiesi USA, Inc.
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CLINICAL_TRIALS trial_result · 2015-01-05Clinical Trial Update: Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major [Phase 2, Phase 3]
This clinical trial evaluated the use of amlodipine to prevent and treat iron overload in patients with thalassemia major; the study has com…
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CLINICAL_TRIALS trial_result · 2014-07-17Clinical Trial Update: MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias
This update reports the completion of a clinical trial evaluating MR imaging to detect diffuse myocardial fibrosis in transfusion-dependent …
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CLINICAL_TRIALS research · 2014-03-11Clinical Trial Update: Role of Vitamin C to Augment Iron Chelation With DFP or DFX [Phase 2, Phase 3]
This clinical trial update describes Phase 2 and Phase 3 studies evaluating whether vitamin C can augment iron chelation with deferiprone or…
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CLINICAL_TRIALS trial_result · 2013-05-01Clinical Trial Update: Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia [Phase 2]
Phase 2 trial evaluating stem cell transplantation after reduced-dose chemotherapy for sickle cell disease or thalassemia. The study has bee…
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FDA approval · 2012-06-20FDA Approved: DEFEROXAMINE — Supplemental Application (Fresenius Kabi USA, LLC)
FDA approved a supplemental application for Deferoxamine Mesylate (Deferoxamine) from Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS research · 2012-02-23Clinical Trial Update: Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major
Clinical trial update describing monitoring of erythroid lineage–specific chimerism after allogeneic hematopoietic transplantation in patien…
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CLINICAL_TRIALS trial_result · 2011-08-15Clinical Trial Update: A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload. [Phase 2]
A 4-year extension study of deferasirox for iron chelation in pediatric β-thalassemia major patients with transfusional iron overload comple…
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CLINICAL_TRIALS trial_result · 2011-04-19Clinical Trial Update: The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study [Phase 4]
A Phase 4 clinical trial update examining how vitamin D supplementation affects calcium excretion in patients with thalassemia major, using …
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CLINICAL_TRIALS trial_result · 2008-12-02Clinical Trial Update: Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major [Phase 4]
Phase 4 trial update on intensive combined chelation therapy for iron-induced cardiomyopathy in patients with thalassemia major; the study s…
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CLINICAL_TRIALS trial_result · 2008-08-13Clinical Trial Update: Efficacy Study of the Use of Sequential DFP-DFO Versus DFP [Phase 4]
Phase 4 efficacy trial comparing sequential DFP-DFO chelation versus deferiprone (DFP) alone in patients with beta-thalassemia major.