Testicular Germ Cell Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors [Phase 1]
A Phase 1 trial is evaluating adding Pedmark (sodium thiosulfate) to cisplatin chemotherapy to reduce cisplatin-induced hearing loss in men …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: MAGESTIC Trial: MiRNA in Detecting Active Germ Cell Tumors in Early Suspected and MetastaTIC Disease Trial
A clinical trial called MAGESTIC is evaluating microRNA biomarkers to detect active malignant testicular germ cell tumors in early suspected…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors [Phase 3]
A Phase 3 clinical trial update on active surveillance followed by BEP-like regimens (bleomycin, etoposide, with carboplatin or cisplatin) i…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials [NA]
A clinical trial update describing efforts to improve adolescent and young adult self-reported data in ECOG-ACRIN trials, with trials curren…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Impact of a Physical Activity Program to Reduce Long-term Cancer-related Fatigue in Metastatic Testicular Germ Cell Tumor Patients [NA]
A clinical trial is evaluating a structured physical activity program to reduce long-term cancer-related fatigue in patients with metastatic…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors [Phase 1]
Phase 1 safety and tolerability study of XmAb541 in advanced solid tumors is currently recruiting, investigating ovarian cancer, endometrial…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Prospective Study to Evaluate miRNA371 and Outcomes in Patients With Newly Diagnosed Germ Cell Tumors
A prospective study to evaluate miRNA-371 as a biomarker and collect outcomes in patients with newly diagnosed germ cell tumors, focusing on…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE) [Phase 2]
Phase 2 trial (E-VIRTUE) evaluating enfortumab vedotin with or without pembrolizumab in rare genitourinary tumors is currently recruiting, i…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: 7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy
A study evaluating 7 Tesla MRI neuroimaging in men with testicular germ cell tumors who have hypogonadism and are on androgen replacement th…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for HiFiBiO's HFB200301 as a single agent and in combination with tislelizumab in adults with advanc…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular Cancer [NA]
This is an update on a clinical trial evaluating robot-assisted, indocyanine green (ICG)-guided sentinel node biopsy for testicular cancer, …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. [NA]
This clinical trial update describes a post-treatment program to identify and manage complications related to oncology or hematology treatme…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer. [Phase 2]
A Phase 2 clinical trial evaluating the combination of Dornase alfa and cisplatin for refractory germ cell tumors is currently recruiting.
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CLINICAL_TRIALS withdrawal · 2025-07-02Clinical Trial Update: A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From Sperm [Phase 2]
Phase 2 trial of an investigational cell therapy given with and without an additional investigational product for male patients with testicu…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours [Phase 3]
Phase 3 trial evaluating one cycle of adjuvant BEP chemotherapy in high-risk stage I non-seminomatous germ cell tumor of the testis; the tri…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Paclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell Tumors [Phase 2]
Phase 2 trial updating Paclitaxel plus Gemcitabine in refractory metastatic germ cell tumors (testicular germ cell tumors) and ovarian cance…
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CLINICAL_TRIALS trial_result · 2022-04-27Clinical Trial Update: Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 trial investigating dasatinib combined with ifosfamide, carboplatin, and etoposide in young patients with metastatic or recu…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors [Phase 3]
Phase 3 trial evaluating combination chemotherapy for stage II or stage III germ cell tumors has completed enrollment and posted results. Th…
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors [Phase 3]
Phase 3 trial evaluating combination chemotherapy with bone marrow transplantation for germ cell tumors has completed recruitment.
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FDA approval · 2020-03-05FDA Approved: CARBOPLATIN — Supplemental Application (Apotex Corp.)
The FDA approved a supplemental application for carboplatin filed by Apotex Corp., authorizing changes to an approved generic product.
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Carboplatin, Etoposide, Cyclophosphamide, and Autologous Bone Marrow Transplantation in Patients With Relapsed or Refractory Cancer [Phase 2]
Phase 2 trial evaluating a regimen of carboplatin, etoposide, cyclophosphamide, and autologous bone marrow transplant in relapsed or refract…
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CLINICAL_TRIALS research · 2018-05-11Clinical Trial Update: A Case-control Study to Assess the Association Between Environmental, Domestic and Occupational Exposures and the Risk of Testicular Germ Cell Tumor
This completed clinical trial conducted a case-control study to assess whether environmental, domestic, and occupational exposures are linke…
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors [Phase 2]
Phase 2 trial of combination chemotherapy with pegfilgrastim in previously untreated germ cell tumors has completed, with results posted.
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CLINICAL_TRIALS research · 2017-05-09Clinical Trial Update: Blood Samples From Patients on a Clinical Trial to CINV During HSCT
This is an update on a clinical trial involving collection of blood samples from patients undergoing chemotherapy-induced nausea and vomitin…
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CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer [Phase 2]
Phase 2 trial evaluating combination chemotherapy plus peripheral stem cell transplantation for relapsed germ cell cancer; results have been…