T-cell Non-hodgkin Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating CAR.70, engineered IL-15-transduced cord blood-derived natural killer (NK) cells, in combination with…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pralatrexate with bendamustine and total-body irradiation followed by donor stem cell transplant for r…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment [Phase 1]
Phase 1 trial to assess the safety of the anti-cancer drugs tazemetostat and belinostat in patients with recurrent or refractory lymphomas; …
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma [Phase 1, Phase 2]
Clinical trial update for AUTO4 in TRBC1-positive T-cell lymphomas shows Phase 1/2 results with the study terminated and results posted.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: CD45BE-HSPC + CART-45 Cells [Phase 1]
Phase 1 study evaluating CD45BE-HSPC with CART-45 cells is not yet recruiting and targets B-cell non-Hodgkin lymphoma and Richter transforma…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells [Phase 1]
A Phase 1 clinical trial update on an allogeneic CD7-targeted CAR-T cell therapy for high-risk T-cell malignancies (T-cell acute lymphoblast…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Pembrolizumab and External Beam Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial assessing pembrolizumab with external beam radiation therapy in relapsed or refractory non-Hodgkin lymphoma; the study (NCT032…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Combination With Romidepsin [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pembrolizumab in combination with romidepsin for recurrent or refractory T-cell lymphomas; the study i…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL) [Phase 1]
A Phase 1 trial update indicates recruitment for Senza5 CART5, CD5-deleted CAR T cells, targeting T-cell non-Hodgkin lymphoma.
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant [Phase 1]
Phase 1 study evaluating olaparib in combination with high-dose chemotherapy for relapsed or refractory lymphomas undergoing stem cell trans…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells [Phase 1]
A Phase 1 clinical trial evaluates CD7-targeted CAR-T cells derived from autologous T cells for high-risk T-cell malignancies and is current…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma [Phase 2]
Completed Phase 2 multicenter study assessing high-dose chemotherapy with autologous stem cell transplant followed by romidepsin maintenance…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen [Phase 1]
Phase 1 trial evaluating autologous CD5-targeted CAR T cells for T-cell malignancies expressing CD5, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating dendritic cell therapy with cryosurgery and pembrolizumab in various Non-Hodgkin lymphoma subtypes, w…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: CD7 CAR T-Cell Therapy for r/r T-cell Lymphomas [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating CD7-directed CAR T-cell therapy for relapsed/refractory T-cell lymphomas (including PTCL and CTC…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: CPI-613 in Combination With Bendamustine in Patients With Relapsed/Refractory T-Cell Non-Hodgkin Lymphoma [Phase 2]
Phase 2 study of CPI-613 (devimistat) in combination with bendamustine for relapsed/refractory T-cell non-Hodgkin lymphoma has been terminat…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 dose-escalation and dose-expansion study of anti-CD7 allogeneic CAR T-cells (WU-CART-007) in …
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma [Phase 1, Phase 2]
Clinical trial update reporting results from a Phase 1/2 study of a conditioning regimen using gemcitabine hydrochloride, clofarabine, and b…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Romidepsin and Parsaclisib for the Treatment of Relapsed or Refractory T-Cell Lymphomas [Phase 1]
Phase 1 trial update evaluating the combination of romidepsin and parsaclisib for relapsed or refractory T-cell lymphomas; the study status …
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Lenalidomide and Ipilimumab After Stem Cell Transplant in Treating Patients With Hematologic or Lymphoid Malignancies [Phase 2]
This Phase 2 trial studied the combination of lenalidomide and ipilimumab after stem cell transplantation in patients with hematologic or ly…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: MargheRITA (Remote Intelligence for Therapeutic Adherence) [NA]
A completed clinical trial named MargheRITA (Remote Intelligence for Therapeutic Adherence) sponsored by Advice Pharma Group srl studied tre…
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma [Phase 2]
Phase 2 trial evaluating CD8+ memory T-cells as consolidative therapy after donor non-myeloablative hematopoietic cell transplant in leukemi…
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CLINICAL_TRIALS trial_result · 2020-11-19Clinical Trial Update: Phase I/Ib Study of Nivolumab & Veliparib in Patients With Advanced Solid Tumors & Lymphoma [Phase 1]
This Phase I/Ib trial assesses safety and early efficacy signals for nivolumab plus veliparib in patients with advanced solid tumors and agg…
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]
Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.