T-cell Leukemia
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Multi-centers, Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of Donor-Derived CD7 CAR T Cells in Subjects With Relapsed or Refractory T-cell Leukemia/Lymphoma [Phase 2]
A multi-center, open-label Phase 2 trial evaluating the efficacy and safety of donor-derived CD7 CAR T cells in relapsed or refractory T-cel…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) [Phase 1]
Phase 1 trial results evaluate palbociclib in combination with chemotherapy for pediatric patients with relapsed acute lymphoblastic leukemi…
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: A Phase II Study Of Imtox-25 In Adults With Refractory/Relapsed Cd25 Positive Adult T Cell Leukemia/Lymphoma [Phase 2]
Phase II study of Imtox-25 in adults with refractory/relapsed CD25-positive Adult T Cell Leukemia/Lymphoma has been terminated; results post…
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: Ruxolitinib for Adult T-Cell Leukemia [Phase 1, Phase 2]
Clinical trial update for ruxolitinib in adult T-cell leukemia across Phase 1 and Phase 2, with terminated status and posted results.
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Subcutaneous Recombinant Human IL-15 (s.c. rhIL-15) and Alemtuzumab for People With Refractory or Relapsed Chronic and Acute Adult T-cell Leukemia (ATL) [Phase 1]
Phase 1 trial evaluating subcutaneous recombinant human IL-15 in combination with alemtuzumab for refractory or relapsed adult T-cell leukem…
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CLINICAL_TRIALS trial_result · 2017-09-08Clinical Trial Update: Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia [Phase 1, Phase 2]
Phase I/II trial evaluating LMB-2 with fludarabine and cyclophosphamide in adults with Adult T-Cell Leukemia; study status completed with re…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: A-dmDT390-bisFv(UCHT1) Immunotoxin Therapy for Patients With Cutaneous T-Cell Lymphoma (CTCL) [Phase 2]
Phase 2 trial of A-dmDT390-bisFv(UCHT1) immunotoxin for cutaneous T-cell lymphoma (CTCL) has completed, with results from the study summariz…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: Phase II Study of the Efficacy and Toxicity of Ontak(Registered Trademark) (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia [Phase 2]
Phase II study of denileukin diftitox (Ontak) in adult T-cell leukemia was terminated; results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Anti-Tac for Treatment of Leukemia [Phase 1, Phase 2]
This document reports the completion of Phase 1 and Phase 2 clinical trials of Anti-Tac (muromonab-CD3) for HTLV-1 infection and T-cell leuk…
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CLINICAL_TRIALS trial_result · 2012-01-19Clinical Trial Update: Repeat-Dose of Forodesine Hydrochloride (BCX-1777) Infusion in Patients With Advanced T-Cell Leukemia [Phase 2]
A Phase 2 trial update evaluating repeat-dose infusions of Forodesine Hydrochloride (BCX-1777) in patients with advanced T-cell leukemia.