T-cell Large Granular Lymphocytic Leukemia
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure [Phase 1, Phase 2]
A NHLBI-sponsored Phase 1/2 trial is evaluating ruxolitinib, a JAK1/2 inhibitor, for relapsed/refractory immune bone marrow failure. The stu…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study of Ruxolitinib and Duvelisib in People With Lymphoma [Phase 1]
A Phase 1 clinical trial evaluating the combination of ruxolitinib and duvelisib in patients with T-cell and NK-cell lymphomas is currently …
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia [Phase 1, Phase 2]
This entry notes an ongoing Phase 1/2 clinical trial evaluating oral azacitidine for relapsed or refractory T-cell large granular lymphocyti…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating ruxolitinib for T-cell large granular lymphocytic leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Thalidomide for the Symptomatic Large Granular Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial is testing thalidomide for symptomatic large granular lymphocytic leukemia and related NK-LGL leukemia, currently r…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: JAK1 Inhibitor Golidocitnib for the Treatment of Relapsed/Refractory Indolent T/NK-cell Lymphomas [Phase 2]
Clinical trial update indicates a Phase 2 study of the JAK1 inhibitor golidocitnib for relapsed/refractory indolent T- and NK-cell lymphomas…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Efficacy and Safety of Linperlisib in Relapsed/Refractory Large Granular T Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial investigating the efficacy and safety of Linperlisib in relapsed or refractory T-cell large granular lymphocytic leuk…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: National Longitudinal Cohort of Hematological Diseases-Large Granular Lymphocytic Leukemia
A clinical trial registry entry indicates that the National Longitudinal Cohort of Hematological Diseases focusing on Large Granular Lymphoc…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: ABC008 in Subjects with T-cell Large Granular Lymphocytic Leukemia (T-LGLL) [Phase 1, Phase 2]
A clinical trial update indicates Abcuro's ABC008 is being studied in Phase 1/2 for T-cell Large Granular Lymphocytic Leukemia, with the stu…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL) [Phase 2]
A phase 2 trial of alemtuzumab in myelodysplastic syndrome, aplastic anemia, and T-cell large granular lymphocytic leukemia was terminated, …
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Tipifarnib in Treating Patients With Anemia or Neutropenia and Large Granular Lymphocyte Leukemia [Phase 2]
Phase 2 trial evaluating tipifarnib in patients with anemia or neutropenia and large granular lymphocytic leukemia, including chronic lympho…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy in CD7 Positive Leukemia and Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating CAR-pNK cell immunotherapy for CD7-positive leukemias and lymphomas. The available snippet does n…
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia [Phase 2]
This Phase 2 trial evaluating methotrexate followed by fludarabine in patients with T-cell large granular lymphocytic leukemia was terminate…
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CLINICAL_TRIALS trial_result · 2013-12-03Clinical Trial Update: Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma [Phase 1]
Phase 1 study evaluating the combination of bortezomib and azacitidine in adults with relapsed or refractory T-cell lymphomas; the trial is …
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CLINICAL_TRIALS trial_result · 2006-07-17Clinical Trial Update: Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine [Phase 1]
Phase 1 clinical trial evaluating cyclosporine for treatment of T-cell large granular lymphocytic leukemia-related lymphoproliferative disor…