Systolic Heart Failure
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Paced Heart Rate Acceleration for Cardiac Conditioning [NA]
A new clinical trial is testing paced heart rate acceleration as a conditioning strategy for systolic heart failure and is currently recruit…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: ST2 for the Management of Heart Failure - STADE-HF [NA]
This document provides an update on the completed STADE-HF trial evaluating ST2 for the management of heart failure.
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Technology-Based Intervention to Promote Heart Health After Cardiac Rehab (Mobile4Heart) [NA]
The Mobile4Heart trial, a technology-based intervention to promote heart health after cardiac rehab, completed and posted results on 2025-04…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device) [NA]
A clinical trial evaluating SCD for cardiorenal syndrome in congestive heart failure without a left ventricular assist device has been suspe…
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure [Phase 3]
An update on a Phase 3 trial evaluating injectable Neucardin for improving cardiac function in chronic systolic heart failure; the study has…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure [Phase 3]
A Phase 3 trial comparing arNi and Ace for improving erectile dysfunction in men with reduced ejection fraction heart failure has completed …
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Iron in Patients With Cardiovascular Disease [Phase 3]
Phase 3 clinical trial for iron treatment in cardiovascular disease patients was terminated.
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: A Registry-based Cluster Randomized Trial to Compare the Effect of Spironolactone vs. Eplerenone on Clinical Outcomes in Patients With Symptomatic Systolic Heart Failure [Phase 4]
A registry-based cluster randomized trial comparing spironolactone versus eplerenone in symptomatic systolic heart failure (Phase 4), curren…
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CLINICAL_TRIALS trial_result · 2022-11-30Clinical Trial Update: Platelet Inhibition in Patients With Systolic Heart Failure [Phase 4]
Phase 4 trial update on platelet inhibition in patients with systolic heart failure; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-05-09Clinical Trial Update: Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections. [Phase 3]
A Phase 3 trial evaluated perioperative antibiotic therapy to prevent infections in cardiac implantable electronic devices, with completed s…
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CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: Junctional AV Ablation in CRT-D: JAVA-CRT [NA]
A completed clinical trial (JAVA-CRT) evaluating junctional AV ablation in CRT-D for patients with systolic heart failure and permanent atri…
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CLINICAL_TRIALS trial_result · 2022-01-06Clinical Trial Update: The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation [Phase 4]
A Phase 4 clinical trial update investigates the prognostic impact of high-dose hydralazine in patients with severe systolic heart failure a…
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: ECG for Programming in CRT [NA]
Clinical trial update for programming in cardiac resynchronization therapy (CRT) using ECG; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-12Clinical Trial Update: Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failure [Phase 4]
Phase 4 trial evaluating ferric carboxymaltose effect on intra-myocardial iron load in patients with heart failure with a focus on systolic …
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CLINICAL_TRIALS trial_result · 2019-03-26Clinical Trial Update: GutHeart: Targeting Gut Microbiota to Treat Heart Failure [Phase 2]
Phase 2 clinical trial investigating gut microbiota modulation as a treatment for systolic heart failure; status currently unknown.
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Medical Arm of the Interagency Registry for Mechanically Assisted Circulatory Support
Clinical trial update for the Medical Arm of the Interagency Registry for Mechanically Assisted Circulatory Support completed with results p…
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CLINICAL_TRIALS trial_result · 2018-12-05Clinical Trial Update: Effectiveness of a Repetitive Use of 24-hour Levosimendan Infusions in Patients With Severe Systolic Heart Failure in Order to Prevent Rehospitalizations [Phase 4]
Phase 4 trial evaluating repetitive 24-hour levosimendan infusions for severe systolic heart failure to prevent rehospitalizations.
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Frailty: Prevalence and Response to Left Ventricular Assist Device Therapy in Older Heart Failure Patients
This clinical trial update reports the prevalence of frailty among older heart failure patients and how they respond to left ventricular ass…
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CLINICAL_TRIALS trial_result · 2017-12-21Clinical Trial Update: Study of Efficacy on Cardiac Remodeling of Recombinant Human Neuregulin-1 in Stable Chronic Systolic Heart Failure Patients [Phase 3]
A Phase 3 trial evaluating recombinant human neuregulin-1 for efficacy in cardiac remodeling in stable chronic systolic heart failure was te…
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CLINICAL_TRIALS research · 2016-11-11Clinical Trial Update: Renal Artery Denervation in Chronic Heart Failure Study [Phase 3]
Phase 3 clinical trial evaluating renal artery denervation for chronic systolic heart failure; sponsor Imperial College London; current stat…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: Bilateral Surgical Resection of Carotid Bodies in Patients With Systolic Heart Failure [NA]
This update notes the completion of a clinical trial investigating bilateral carotid body resection in patients with systolic heart failure.
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CLINICAL_TRIALS trial_result · 2016-09-16Clinical Trial Update: Clinical Value of Heart Rate Variability Indexes to Predict Outcomes After Exercise Training in Chronic Heart Failure [Phase 4]
Phase 4 trial update evaluating whether heart rate variability indexes can predict outcomes after exercise training in chronic heart failure…
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CLINICAL_TRIALS trial_result · 2015-08-26Clinical Trial Update: Repurposing Probenecid as a Positive Inotrope for the Treatment of Heart Failure [Phase 2]
A Phase 2 clinical trial examining repurposed Probenecid as a positive inotrope for systolic heart failure has completed.
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CLINICAL_TRIALS research · 2014-12-16Clinical Trial Update: Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism [Phase 4]
Phase 4 clinical trial update examining the effects of levothyroxine supplementation in patients with systolic heart failure and subclinical…
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Psychosocial Patterns and Prognosis in Patients With Heart Failure
Completed clinical trial update examining psychosocial patterns and prognosis in patients with Systolic heart failure and Diastolic heart fa…