Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's Phenomenon [Phase 3]
Phase 3 clinical trial evaluating fasudil, a Rho-kinase inhibitor, for Raynaud's phenomenon (including scleroderma) has completed and posted…
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CLINICAL_TRIALS trial_result · 2014-10-27Clinical Trial Update: A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis [Phase 1, Phase 2]
This update covers a Phase 1/2 trial of Imatinib (Gleevec) in systemic sclerosis and alveolitis, with results posted after completion.
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Assessment of the Subcutaneous Reinjection of Human Autologous Adipose-derived Stromal Vascular Fraction (Celution® System) in the Hands of Patients Suffering From Systemic Sclerosis [NA]
Clinical trial update reporting the completion of a study evaluating subcutaneous reinjection of autologous adipose-derived stromal vascular…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis Patients Treated With ABR-215757 (Paquinimod) [Phase 2]
An open-label Phase 2 trial evaluated biomarkers and safety of paquinimod (ABR-215757) in patients with systemic sclerosis. The study has co…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: High Dose Cyclophosphamide for Treatment of Scleroderma [Phase 3]
A Phase 3 trial evaluating high-dose cyclophosphamide for systemic sclerosis has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Finger Hardness Measure in Scleroderma
A Mayo Clinic-sponsored trial assessing finger hardness as a biomarker in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: Small Intestinal Mucosal Abnormalities in Systemic Sclerosis Using Capsule Endoscopy
A completed clinical trial evaluating small intestinal mucosal abnormalities in systemic sclerosis using capsule endoscopy.
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CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma [Phase 2]
Phase 2 trial evaluating cyclophosphamide and rabbit anti-thymocyte globulin with hematopoietic stem cell support in systemic sclerosis; res…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine [Phase 2]
Phase 2 trial investigating oral treprostinil diethanolamine for digital ischemic lesions in systemic sclerosis (scleroderma) completed with…
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Hemodynamic Changes in Connective Tissue Disease
A completed clinical trial update investigating hemodynamic changes in systemic sclerosis (a connective tissue disease).
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: Open-Label Study of Oral Treprostinil in Digital Ulcers [Phase 2]
An open-label Phase 2 trial evaluating oral treprostinil for digital ulcers in systemic sclerosis was terminated, with results posted in Feb…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY [Phase 3]
A Phase 3 clinical trial (SEDUCE) investigating sildenafil for healing digital ulcers in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2014-01-23Clinical Trial Update: Morbidity and Mortality Follow Up for the Scleroderma Lung Study
This release provides morbidity and mortality follow-up data from the Scleroderma Lung Study, presenting long-term outcomes for participants…
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CLINICAL_TRIALS trial_result · 2013-07-15Clinical Trial Update: Digital Ulceration
Clinical trial investigating digital ulcers in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement [NA]
This completed clinical trial evaluated the safety and efficacy of mycophenolate mofetil in patients with systemic sclerosis (scleroderma) w…
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CLINICAL_TRIALS trial_result · 2013-04-16Clinical Trial Update: Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up
Results of a five-year prospective, manometric follow-up study examining small bowel motor impairment in systemic sclerosis (scleroderma) ar…
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CLINICAL_TRIALS trial_result · 2013-03-22Clinical Trial Update: Randomised Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma [Phase 3]
A Phase 3 randomized trial evaluating tadalafil for Raynaud's phenomenon in patients with scleroderma has completed.
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: Sonographic and Laboratory Evaluation of the Thyroid Gland in Patients With Systemic Sclerosis
This completed clinical trial evaluated sonographic and laboratory assessment of the thyroid gland in patients with systemic sclerosis, incl…
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CLINICAL_TRIALS trial_result · 2013-02-11Clinical Trial Update: Efficacy and Safety Study of p144 to Treat Skin Fibrosis in Systemic Sclerosis [Phase 2]
A Phase 2 study evaluating p144 for skin fibrosis in systemic sclerosis has completed, reporting efficacy and safety data. The sponsor is IS…
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CLINICAL_TRIALS trial_result · 2012-12-18Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Systemic Sclerosis [Phase 1]
A Phase 1 study evaluating allogeneic hematopoietic stem cell transplantation for systemic sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2012-10-23Clinical Trial Update: Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis [Phase 1]
This is a Phase 1 pharmacokinetics study evaluating how oral treprostinil is processed in patients with systemic sclerosis. It assesses abso…
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Sacroiliitis in Systemic Sclerosis
A clinical trial investigating sacroiliitis in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2012-08-17Clinical Trial Update: Imatinib in Systemic Sclerosis [Phase 1, Phase 2]
Phase 1/2 clinical trial of imatinib in systemic sclerosis completed with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: Investigation of Coronary and Pulmonary Circulatory Parameters in Systemic Sclerosis
A completed clinical trial assessing coronary and pulmonary circulatory parameters in individuals with systemic sclerosis; results of the st…
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CLINICAL_TRIALS trial_result · 2012-05-08Clinical Trial Update: A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma [Phase 1]
This document reports the completion of a Phase 1 trial evaluating the safety and tolerability of multiple doses of MEDI-546 in adults with …