Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases [Phase 1]
Phase 1 trial update on nonmyeloablative allogeneic stem cell transplantation for systemic lupus erythematosus and systemic sclerosis, with …
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: FOLLOW HEART TRANSPLANT FOR ACHIEVING THE HEART PRIMITIVE RELATED SCLERODERMA SYSTEMIC
ClinicalTrials.gov entry describes a study investigating heart transplantation in relation to systemic sclerosis (scleroderma). Sponsor is U…
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CLINICAL_TRIALS trial_result · 2016-06-15Clinical Trial Update: Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Disease [Phase 2]
A Phase 2 trial evaluating the combination of imatinib and rituximab for cutaneous sclerosis in chronic graft-versus-host disease has comple…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis
Clinical trial update reporting treatment outcomes in early diffuse cutaneous systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Light Treatment for Scleroderma Finger Ulcers [NA]
A clinical trial evaluating light therapy for finger ulcers in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Rapamycin vs Methotrexate in Diffuse SSc [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial comparing rapamycin versus methotrexate in diffuse systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Proof of Biological Activity of SAR100842 in Systemic Sclerosis [Phase 2]
Phase 2 trial of SAR100842 in systemic sclerosis demonstrated biological activity, providing proof of concept in a completed study.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis [NA]
This update notes the completion of a clinical trial evaluating soluble VE-cadherin and VE-cadherin antibody in primary Raynaud's disease an…
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CLINICAL_TRIALS trial_result · 2016-03-22Clinical Trial Update: Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis [Phase 2]
A Phase 2 study evaluated acute peripheral vascular effects, safety and tolerability in patients with Raynaud's phenomenon secondary to syst…
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Thalidomide for Decreasing Collagen Biosynthesis in People With Progressive Systemic Sclerosis [Phase 1]
Phase 1 trial evaluating thalidomide for decreasing collagen biosynthesis in progressive systemic sclerosis. The study has been terminated.
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Evaluating Lung Doppler Signals in Patients With Systemic Sclerosis (SSc) [NA]
The clinical trial evaluating lung Doppler signals in patients with systemic sclerosis and pulmonary hypertension has been terminated.
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Detecting Pulmonary Arterial Hypertension (PAH) in Patients With Systemic Sclerosis (SSc) by Ultrasound [NA]
A clinical trial evaluating ultrasound-based detection of pulmonary arterial hypertension in patients with systemic sclerosis was terminated…
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough
A completed clinical trial update evaluating the role of gastroesophageal reflux, microaspiration, and cough in scleroderma lung.
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CLINICAL_TRIALS trial_result · 2015-11-05Clinical Trial Update: A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating tocilizumab (RoActemra/Actemra) versus placebo in systemic sclerosis has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Post Marketing Surveillance Study of Cuprimine
This clinical trial update covers a post-marketing surveillance study of Cuprimine (penicillamine) for systemic sclerosis. The study is no l…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Safety and Tolerability of Pirfenidone in Participants With Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD) (LOTUSS) [Phase 2]
A Phase 2 trial (LOTUSS) evaluated the safety and tolerability of pirfenidone in systemic sclerosis-related interstitial lung disease (SSc-I…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Immunoadsorption in Patients With Severe Systemic Sclerosis [NA]
The clinical trial update indicates that the immunoadsorption study in patients with severe systemic sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: UVA1 Light for Treatment of Scleroderma and Similar Conditions [NA]
Completed clinical trial evaluating UVA1 light therapy for systemic sclerosis (scleroderma) and keloids.
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CLINICAL_TRIALS trial_result · 2015-04-24Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma) [Phase 1, Phase 2]
Completed Phase 1/2 study evaluating abatacept for diffuse systemic sclerosis (scleroderma); results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Scleroderma Lung Disease [Phase 3]
Phase 3 trial for systemic sclerosis–associated lung disease has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders [Phase 1]
Completed Phase 1 pilot study evaluating total body irradiation with cyclophosphamide, anti-thymocyte globulin, and autologous CD34-selected…
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update reports safety, tolerability, and pharmacokinetics data for CAT-192, a human anti-TGF-beta1 monoclon…
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CLINICAL_TRIALS trial_result · 2015-01-28Clinical Trial Update: Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients [Phase 3]
A Phase 3 trial evaluating macitentan for digital ulcers in systemic sclerosis was terminated, and results were posted in January 2015.
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients [Phase 3]
Macitentan was studied in a Phase 3 trial for treating digital ulcers in systemic sclerosis; results were posted January 6, 2015.
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: A Study of the Safety and Tolerability of MEDI-551 in Scleroderma [Phase 1]
This document summarizes the results of a Phase 1 study evaluating the safety and tolerability of MEDI-551 (inebilizumab) in patients with s…