Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-12Clinical Trial Update: The Scleroderma Patient-centered Intervention Network (SPIN) Support Group Leader Education Program Feasibility Trial [NA]
Feasibility trial evaluating a leader education program for scleroderma support groups; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-12-13Clinical Trial Update: A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis [Phase 3]
Phase 3 trial comparing nintedanib to placebo in scleroderma-related lung fibrosis completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-10-18Clinical Trial Update: Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung Disease [Phase 2]
Phase 2 trial evaluating pomalidomide (CC-4047) for systemic sclerosis with interstitial lung disease was terminated; results posted in 2019…
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CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: Riociguat in Scleroderma Associated Digital Ulcers [Phase 2]
A Phase 2 trial update on riociguat for digital ulcers associated with scleroderma has completed, with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-15Clinical Trial Update: Taking Charge of Systemic Sclerosis [NA]
Clinical trial update for systemic sclerosis (scleroderma) with completed status and posted results.
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CLINICAL_TRIALS trial_result · 2019-07-30Clinical Trial Update: Effectiveness of Saccharomyces Boulardii for Gastrointestinal Bacterial-overgrowth in Systemic Sclerosis [Phase 4]
Phase 4 clinical trial evaluating the effectiveness of Saccharomyces boulardii for gastrointestinal bacterial overgrowth in systemic scleros…
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Scleroderma ARFI Imaging of the Skin
Clinical trial update on ARFI imaging of the skin in scleroderma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-04-03Clinical Trial Update: A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc) [Phase 3]
Phase 3 trial update on efficacy and safety of tocilizumab in systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-03-13Clinical Trial Update: Gut Microbiota Transplantation in Systemic Sclerosis [Phase 1, Phase 2]
Clinical trial update on gut microbiota transplantation for systemic sclerosis (scleroderma) across Phase 1 and Phase 2, status completed.
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating riociguat for systemic sclerosis has completed; results posted in 2019 with data on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2018-12-13Clinical Trial Update: The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis [Phase 4]
A Phase 4 clinical trial assessing the effects of bosentan on arterial stiffness in patients with systemic sclerosis (scleroderma).
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CLINICAL_TRIALS trial_result · 2018-11-29Clinical Trial Update: Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis [NA]
Completed clinical trial evaluating ambrisentan in combination with an antifibrotic agent for diffuse systemic sclerosis; results posted in …
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Hands on - a Hand Care Guide in Systemic Sclerosis [NA]
A completed clinical trial update for a hand care guide in systemic sclerosis (scleroderma) with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-10Clinical Trial Update: Clinical Trial of Probiotics in Systemic Sclerosis Associated Gastrointestinal Disease [Phase 2]
Phase 2 clinical trial update for probiotics in systemic sclerosis-related gastrointestinal disease.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Mechanisms of Pulmonary Diffusion Limitation in Systemic Sclerosis
This completed clinical trial investigated mechanisms of diffusion limitation of pulmonary gas exchange in patients with systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: IVIG Treatment in Systemic Sclerosis [NA]
Clinical trial update on intravenous immunoglobulin (IVIG) treatment for systemic sclerosis, including the diffuse cutaneous form; the trial…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma [Phase 1]
A Phase 1 trial assessing the safety and suitability of dabigatran to inhibit thrombin in patients with scleroderma has completed. The study…
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis [Phase 1]
This clinical trial update reports on the prevalence and predictors of partial response to proton pump inhibitors in gastroesophageal reflux…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung Disease [Phase 3]
A Phase 3 trial comparing mycophenolate mofetil for systemic sclerosis-related early interstitial lung disease has completed.
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis [Phase 1, Phase 2]
This document reports the completion of a Phase 1/2 trial evaluating allogeneic hematopoietic cell transplantation for severe systemic scler…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR) [NA]
A completed clinical trial evaluated Celution processed adipose-derived regenerative cells (STAR) for treating scleroderma (systemic scleros…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: IL1-TRAP, Rilonacept, in Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports on IL1-TRAP (rilonacept) for systemic sclerosis (scleroderma), with the study completed and result…
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Imatinib Mesylate (Gleevec) in the Treatment of Systemic Sclerosis [Phase 2]
Phase 2 clinical trial of imatinib mesylate (Gleevec) for systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: A Pilot-Study of Sirolimus for the Treatment of Systemic Sclerosis [Phase 2]
An update on a Phase 2 pilot study evaluating sirolimus as a treatment for systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis [NA]
A completed clinical trial evaluating neuropsychiatric involvement in systemic sclerosis.