Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc) [Phase 2]
An open-label extension trial of HZNP-HZN-825-301 in adults with diffuse cutaneous systemic sclerosis was terminated; results have been post…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: 7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis [NA]
A clinical trial evaluated 7.0 Tesla MRI of the hand in systemic sclerosis. The study status is completed.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Role of Eosinophil in Fibrogenesis of Systemic Sclerosis
A completed clinical trial investigating the role of eosinophils in the fibrogenesis of systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Description of the Functional Evolution of Diffuse Infiltrating Pneumonia Associated With Systemic Scleroderma.
A completed clinical trial update describes the functional evolution of diffuse infiltrating pneumonia in patients with systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Clinical Relevance of Thoracic Echography for the Early Diagnosis of Interstitial Lung Disease in Systemic Scleroderma - Pilot Study [NA]
A completed pilot study evaluating whether thoracic echography can aid early diagnosis of interstitial lung disease in systemic sclerosis. T…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Skin Fibrosis Analysis by Raman Spectroscopy in Systemic Sclerosis
The clinical trial evaluating Raman spectroscopy for assessing skin fibrosis in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease [Phase 1]
A Phase 1 safety and efficacy study of CTX112 in adults with refractory autoimmune diseases, including systemic lupus erythematosus and syst…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Study of MT-0551 in Patients With Systemic Sclerosis [Phase 3]
Phase 3 clinical trial update for MT-0551 in systemic sclerosis, currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Evaluation of Calcinosis in Systemic Sclerosis
A clinical trial evaluating calcinosis in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases [Phase 4]
Phase 4 clinical trial update on the recombinant herpes zoster vaccine in patients with autoimmune rheumatic diseases; the study is active b…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma [Phase 3]
Phase 3 trial evaluating topical cannabidiol lotion for pruritus relief in systemic sclerosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Rituximab in Systemic Sclerosis [Phase 2, Phase 3]
Rituximab is being evaluated for systemic sclerosis in Phase 2 and Phase 3 trials, and the study has completed.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Systemic Sclerosis' Relatives Reflex
The clinical trial investigating systemic sclerosis and caregiver-related outcomes has completed.
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating autologous stem cell transplantation in systemic sclerosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT [NA]
Pilot study imaging systemic sclerosis with CXCR4-targeted PET/CT to visualize inflammatory activity has completed.
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Quantification and Characterization of Circulating Epithelial and Endothelial Cells in Gougerot-Sjögren Syndrome, Compared to Systemic Sclerosis [NA]
A completed clinical trial comparing circulating epithelial and endothelial cells in primary Sjögren's syndrome and diffuse systemic scleros…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease [Phase 3]
This clinical trial update notes the completion of a Phase 3 study evaluating cyclophosphamide for systemic sclerosis-associated interstitia…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Intralesional Injection of STS in Treatment of Calcinosis [Phase 2]
A Phase 2 clinical trial evaluating intralesional sodium thiosulfate for calcinosis associated with systemic sclerosis and other connective …
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: A Study of Cizutamig in Systemic Sclerosis [EARLY_Phase 1]
This document reports an early phase 1 clinical trial evaluating Cizutamig in patients with Systemic sclerosis, with the study status listed…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders [Phase 2]
This Phase 2 trial evaluating a COVID-19 booster vaccine in autoimmune-disease non-responders was terminated, with results posted on 2025-08…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: RENEW-AI: Personalizing Scleroderma Management With an AI Health Coach [NA]
This update reports the completion of the RENEW-AI trial evaluating an AI health coach to personalize management of systemic sclerosis (scle…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Metabolomic Analysis of Systemic Sclerosis
The ClinicalTrials.gov update reports that the metabolomic analysis study of systemic sclerosis and related connective tissue diseases has b…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: A Study of MK-2225 in Healthy Participants (MK-2225-003) [Phase 1]
Phase 1 trial MK-2225-003 in healthy participants has completed, sponsored by Merck Sharp & Dohme LLC, with systemic sclerosis listed as the…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: A Study of KHK4827 in Patients With Systemic Sclerosis [Phase 1]
The Phase 1 trial of KHK4827 in systemic sclerosis has completed. No results are provided in the summary.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis [Phase 3]
Phase 3 study of KHK4827 in moderate-to-severe systemic sclerosis has completed. The update does not include efficacy or safety results.