Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-03-07Clinical Trial Update: Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma [Phase 2]
A Phase 2 proof-of-concept trial of imatinib (Gleevec) in active diffuse systemic sclerosis (scleroderma) has been terminated.
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CLINICAL_TRIALS trial_result · 2012-02-29Clinical Trial Update: Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary Fibrosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety of dasatinib in patients with scleroderma-associated pulmonary fibrosis. The study has comp…
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Mycophenolate Mofetil
This completed clinical trial investigated skin biopsy biomarkers in systemic sclerosis and their relation to response to mycophenolate mofe…
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CLINICAL_TRIALS trial_result · 2011-09-23Clinical Trial Update: Early Therapy of Pulmonary Arterial Hypertension [NA]
This entry reports a completed clinical trial evaluating early therapy for pulmonary arterial hypertension. The trial was sponsored by the M…
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Placebo Controlled Trial of Bosentan in Scleroderma Patients [Phase 2]
A phase 2 placebo-controlled trial of bosentan in patients with systemic sclerosis and pulmonary hypertension was terminated; results were p…
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CLINICAL_TRIALS trial_result · 2011-05-30Clinical Trial Update: Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome [Phase 3]
Phase 3 clinical trial update for moderate to severe dry eye syndrome, sponsored by Allergan, involving patients with Keratoconjunctivitis S…
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CLINICAL_TRIALS trial_result · 2011-03-31Clinical Trial Update: Mycophenolate Mofetil in Systemic Sclerosis [Phase 1]
Phase 1 clinical trial of mycophenolate mofetil for diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2011-03-04Clinical Trial Update: Efficacy and Safety of Imatinib in Scleroderma [Phase 2]
Phase 2 trial of imatinib in systemic sclerosis and localized scleroderma has completed, with reported efficacy and safety outcomes.
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Premature Coronary Atherosclerosis in Scleroderma
A completed clinical trial update examining premature coronary atherosclerosis in systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2010-07-30Clinical Trial Update: Efficacy and Safety Study of GB-0998 for Treatment of Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating the efficacy and safety of GB-0998 for systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2010-06-28Clinical Trial Update: Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases [Phase 4]
Phase 4 study assessing the safety and efficacy of an H1N1 vaccine in patients with rheumatic diseases. The current status of the trial is u…
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CLINICAL_TRIALS trial_result · 2010-05-25Clinical Trial Update: Oral Type I Collagen for Relieving Scleroderma [Phase 2]
Phase 2 clinical trial update evaluating oral type I collagen for systemic sclerosis (scleroderma) has completed.
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CLINICAL_TRIALS trial_result · 2010-05-10Clinical Trial Update: A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma [Phase 3]
A Phase 3 randomized trial evaluated the efficacy of tadalafil for Raynaud's phenomenon and digital ulcers in systemic sclerosis; the study …
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CLINICAL_TRIALS trial_result · 2010-03-09Clinical Trial Update: Sleep Disturbances and Pulmonary Artery/Aorta Diameter in Scleroderma Patient
A completed clinical trial update examining sleep disturbances and pulmonary artery to aorta diameter in a patient with systemic sclerosis (…
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CLINICAL_TRIALS trial_result · 2009-12-02Clinical Trial Update: Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc) [Phase 1]
Phase 1 trial evaluating reduced-intensity transplant for medically refractory systemic lupus erythematosus and systemic sclerosis was termi…
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CLINICAL_TRIALS trial_result · 2009-10-27Clinical Trial Update: Influenza Vaccination in Patients With Scleroderma [Phase 4]
Phase 4 clinical trial update evaluating influenza vaccination in patients with systemic sclerosis (scleroderma).
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CLINICAL_TRIALS trial_result · 2009-09-25Clinical Trial Update: Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension [Phase 3]
A Phase 3 clinical trial evaluating rosuvastatin for systemic sclerosis-related pulmonary hypertension has completed.
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CLINICAL_TRIALS trial_result · 2009-09-03Clinical Trial Update: Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement [Phase 2]
This entry notes a Phase 2 trial evaluating low-dose oral imatinib for pulmonary involvement in systemic sclerosis (scleroderma); the trial …
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CLINICAL_TRIALS trial_result · 2009-07-27Clinical Trial Update: The Effect of Physical Therapy on Raynaud's Phenomenon Secondary to Systemic Sclerosis [NA]
A completed clinical trial evaluated the effect of physical therapy on Raynaud's phenomenon in patients with systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2009-06-12Clinical Trial Update: Treatment of Early Systemic Sclerosis by Bosentan [Phase 1, Phase 2]
This clinical trial update reports that the Phase 1/2 study of bosentan for early systemic sclerosis was terminated.
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CLINICAL_TRIALS trial_result · 2009-01-07Clinical Trial Update: Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial investigating sildenafil for the treatment of active digital ulcers in systemic sclerosis; the study status is comple…
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CLINICAL_TRIALS trial_result · 2008-09-03Clinical Trial Update: Phase II Pilot Study of Cyclophosphamide and Rabbit Anti-Thymocyte Globulin as Salvage Therapy in Patients With Diffuse Systemic Sclerosis [Phase 2]
Phase II pilot trial evaluating cyclophosphamide plus rabbit anti-thymocyte globulin as salvage therapy in diffuse systemic sclerosis has co…
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CLINICAL_TRIALS trial_result · 2008-08-22Clinical Trial Update: Effectiveness and Safety of Lidocaine for Scleroderma [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluated the effectiveness and safety of lidocaine for systemic sclerosis (scleroderma) and has completed.
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CLINICAL_TRIALS trial_result · 2008-06-30Clinical Trial Update: Trial of IC351 in Female Scleroderma Patients With Raynaud's and Sexual Dysfunction [Phase 2]
Phase 2 trial of IC351 in female Systemic Sclerosis patients with Raynaud's phenomenon and sexual dysfunction has completed.
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CLINICAL_TRIALS trial_result · 2008-06-25Clinical Trial Update: Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma [Phase 3]
Phase 3 trial of Recombinant Human Relaxin for diffuse scleroderma (systemic sclerosis) has completed.