Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
A long-term follow-up study for participants previously treated with KYV-101; recruitment is ongoing across multiple autoimmune diseases.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Study of AZD0120 in Autoimmune Diseases [Phase 1]
AZD0120 from AstraZeneca is in Phase 1 testing for autoimmune diseases, including systemic sclerosis, idiopathic inflammatory myopathies, an…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Correlation Between Circulating Fibroblast Activation Protein (FAP) and Fibrosis in Two Diseases (Rheumatoid Arthritis and Systemic Sclerosis)
A Sohag University-led clinical trial investigates whether circulating fibroblast activation protein (FAP) levels correlate with fibrosis in…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Platform Clinical Study for Conquering Scleroderma [Phase 2]
Phase 2 platform clinical study to conquer systemic sclerosis (scleroderma) is currently recruiting, with a focus on interstitial lung disea…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating human umbilical cord-derived mesenchymal stromal cells for systemic sclerosis; currently recruiting.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease [Phase 1]
Phase 1 clinical trial update for a CAR T-cell therapy targeting CD19 and BCMA in autoimmune conditions, with recruiting status and potentia…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases [EARLY_Phase 1]
Early-phase clinical study of a targeted CD19/BCMA CAR-T therapy for autoimmune diseases is recruiting, including systemic lupus erythematos…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Transcriptomic Study of Cutaneous Fibroblasts in Scleroderma
This recruiting study investigates gene expression in cutaneous fibroblasts from patients with systemic sclerosis (scleroderma) to understan…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Baricitinib in Systemic Sclerosis [Phase 4]
A Phase 4 clinical trial is evaluating the efficacy and safety of baricitinib for systemic sclerosis. The study is currently active but not …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases [NA]
This entry reports on a clinical trial evaluating patient-reported outcomes of UVA-1 phototherapy for treating sclerosing skin diseases, inc…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases [Phase 1]
Phase 1 trial evaluating autologous CD19/BCMA dual-target CAR-T therapy for relapsed/refractory autoimmune diseases; currently recruiting at…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Safety and Efficacy of Adipose-Derived Regenerative Cells (ADRCs) for Improving Hand Dysfunction in Systemic Sclerosis [NA]
A clinical trial update indicates ongoing recruitment for assessing the safety and efficacy of adipose-derived regenerative cells (ADRCs) to…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Safety, Efficacy and Cellular Metabolic Dynamics of CT1195E in Patients With Refractory / Progressive SSC [EARLY_Phase 1]
An early Phase 1 trial update for CT1195E in patients with refractory or progressive systemic sclerosis, with recruitment ongoing.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial evaluating QT-019C, a CD19 and BCMA-targeted CAR T-cell therapy, for relapse/refractory autoimmune diseases; recrui…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Western Sweden Systemic Sclerosis Project
A systemic sclerosis (scleroderma) trial in Western Sweden, sponsored by Sahlgrenska University Hospital, is currently recruiting and evalua…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Familial Systemic Scleroderma
A clinical trial update shows that a study investigating familial systemic sclerosis (systemic scleroderma) is currently recruiting in Stras…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Longitudinal Spatial Frequency Domain Imaging Study [NA]
Boston University is conducting a longitudinal Spatial Frequency Domain Imaging study for systemic sclerosis (NCT05672992). The trial is cur…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Diffuse Cutaneous Scleroderma (DSSc) SFDI Study [NA]
This clinical trial update notes that the Diffuse Cutaneous Scleroderma SFDI study (NCT07090226) sponsored by Boston University is currently…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease [Phase 2, Phase 3]
Clinical trial update on belimumab for systemic sclerosis-associated interstitial lung disease, spanning Phase 2 and Phase 3, currently recr…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis [Phase 2]
A Phase 2 trial update evaluating the safety and tolerability of TOP-N53 applied to digital ulcers in systemic sclerosis, with recruitment o…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life [NA]
Update on a clinical trial evaluating the Apollo Device for systemic sclerosis, targeting fatigue, Raynaud phenomenon, and quality of life.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Duke University’s MADRA pregnancy autoimmune disease registry is actively recruiting to study autoimmune conditions during pregnancy, includ…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma. [Phase 2]
A Phase 2 clinical trial is evaluating subcutaneous injections of ASC to heal digital ulcers in systemic sclerosis. The study is currently r…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases [NA]
This clinical trial is recruiting to evaluate anti-CD19 IL-10/IL-15 CAR-NK cells for refractory/relapsed autoimmune diseases. Conditions inc…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Analysis of Dermal Fibroblasts and Immune Cells During Systemic Sclerosis
This clinical trial from University Hospital, Lille is recruiting to analyze dermal fibroblasts and immune cells in patients with systemic s…