Systemic Sclerosis
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial evaluating safety and efficacy of CABA-201, a CD19-CAR T cell therapy, in adults with systemic sclerosis…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of subcutaneous Efgartigimod with PH20 technology in adults with systemic sclerosi…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating the safety of CD19-targeted CAR-T cell therapy produced at Gustave Roussy for adults with severe and refra…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Trichoscopy and Systemic Scleroderma
This entry notes an ongoing clinical trial sponsored by University Hospital Lille evaluating trichoscopy in systemic sclerosis. Recruitment …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Objective Assessment of Skin Damage Using ADHELASKIN in Patients With Systemic Sclerosis [NA]
A clinical trial investigating the objective assessment of skin damage in systemic sclerosis using ADHELASKIN; study status is NOT_YET_RECRU…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Systemic Sclerosis [Phase 1, Phase 2]
This clinical trial is evaluating Umbilical Cord Mesenchymal Stem Cells for systemic sclerosis in Phase 1/2 and is currently not recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) [Phase 3]
DAISY is a Phase 3 trial evaluating the effectiveness of anifrolumab in systemic sclerosis; the study is currently active but not recruiting…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Efficacy and Safety of Firsekibart in the Treatment of Systemic Sclerosis [NA]
Clinical trial update discussing the efficacy and safety of Firsekibart in treating systemic sclerosis, with the study status showing NOT_YE…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Brain Boost Program to Improve Cognitive Function in People With Systemic Sclerosis [NA]
A University of Michigan-sponsored clinical trial is evaluating a cognitive training program called Brain Boost to improve cognitive functio…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MTS109 in Patients With Refractory Autoimmune Diseases [EARLY_Phase 1]
A Phase 1 clinical trial evaluating MTS109 in adults with refractory autoimmune diseases is currently recruiting. The study includes systemi…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis [Phase 3]
A Phase 3 clinical trial is evaluating nerandomilast for systemic sclerosis, with recruitment not yet started.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders [Phase 1, Phase 2]
Phase I/II trial of AD-PluReceptor plus tafasitamab-cxix with lymphodepleting chemotherapy in autoimmune disorders is currently recruiting, …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Controlling Hyperactive Immunity With Long-lived Lymphocytes [Phase 1, Phase 2]
Quell Therapeutics is running Phase 1/2 trials to control hyperactive immunity with long-lived lymphocytes, enrolling participants with diff…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension [Phase 2]
An update on a Phase 2 trial of oral Ifetroban for diffuse cutaneous systemic sclerosis and SSc-associated pulmonary arterial hypertension, …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases [Phase 4]
Phase 4 clinical trial assessing safety and immunogenicity of the live attenuated tetravalent Butantan-Dengue vaccine in autoimmune rheumati…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of BEN301 Injection in theTreatment of Autoimmune Diseases [EARLY_Phase 1]
A Phase 1 study of BEN301 Injection for multiple autoimmune diseases is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of CC312 for Relapsed/Refractory Autoimmune Diseases [EARLY_Phase 1]
This is an early-phase 1 study evaluating CC312 for relapsed/refractory autoimmune diseases, including systemic lupus erythematosus, idiopat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs） [Phase 1]
Phase 1 trial update showing that HN2301 is being studied for autoimmune diseases with ongoing recruitment, including systemic lupus erythem…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of BEN301 Injection in the Treatment of Autoimmune Diseases [EARLY_Phase 1]
Early Phase 1 clinical trial update for BEN301 injection evaluating safety in autoimmune diseases including systemic sclerosis, rheumatoid a…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease [Phase 3]
Phase 3 clinical trial evaluating the combination of nintedanib and tocilizumab for systemic sclerosis with interstitial lung disease is cur…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease [Phase 1]
Phase 1 clinical trial update for ALLO-329, an allogeneic CAR T-cell therapy, in adults with autoimmune diseases including systemic lupus er…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of KITE-363 in Participants With Refractory Autoimmune Diseases [Phase 1]
Phase 1 study evaluating KITE-363 in participants with refractory autoimmune diseases, currently enrolling by invitation, including systemic…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2) [Phase 1, Phase 2]
This is a clinical trial update for a Phase 1/2 study of NKX019 in immune‑mediated diseases, currently recruiting to assess safety and early…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease [EARLY_Phase 1]
An early-phase trial of allogeneic CD19/BCMA CAR-T therapy for B-cell–related autoimmune diseases is recruiting at The Children's Hospital o…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis [Phase 2]
This is a Phase 2 clinical trial update evaluating nemolizumab for adults with systemic sclerosis; the study is currently recruiting.