Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB [NA]
This entry provides an update on the HOP-STEP intervention trial aimed at improving maternal health in women with Systemic Lupus Erythematos…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase exploratory clinical study evaluating the safety and potential efficacy of an anti-CD19/BCMA U CAR-T cell therapy for relapse…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease [Phase 3]
Phase 3 trial evaluating outcomes after stopping hydroxychloroquine in elderly patients with systemic lupus erythematosus; currently recruit…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus [Phase 1]
Phase 1 trial evaluating CD19 CAR T-cell therapy for refractory systemic lupus erythematosus is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Saphnelo Use in Females of Child-bearing Potential
This clinical trial update indicates the use of Saphnelo (anifrolumab) in females of child-bearing potential for systemic lupus erythematosu…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis [Phase 3]
Phase 3 clinical trial update for Anifrolumab in adults with active proliferative lupus nephritis; the study is currently active but not rec…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases [Phase 2]
This Phase 2 master protocol trial, sponsored by Amgen, is evaluating Inebilizumab and Blinatumomab in autoimmune diseases. It is currently …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Treatment Effectiveness Study Among SLE Patients Receiving Anifrolumab in Routine Clinical Practice
A treatment-effectiveness study evaluating Anifrolumab for systemic lupus erythematosus in routine clinical practice is currently active but…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus [Phase 3]
A Phase 3 trial to evaluate subcutaneous anifrolumab for systemic lupus erythematosus in immunosuppressant-naïve and biologic-naïve patients…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CART19, autologous CD19-directed CAR T cells, for systemic lupus erythematosus and lupus nephritis.…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus
This clinical trial update notes a study in pediatric systemic lupus erythematosus investigating whether early myocardial dysfunction can id…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN) [Phase 2]
Phase 2 clinical trial update for rapcabtagene autoleucel in active, refractory systemic lupus erythematosus and lupus nephritis, currently …
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE [Phase 3]
A Phase 3 clinical trial evaluated the efficacy, safety, tolerability, and pharmacokinetics/pharmacodynamics of emapalumab in children and a…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial of TI-0032-III Injection for relapsed and refractory autoimmune diseases is currently recruiting, encompassing seve…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by NHLBI is evaluating nicotinamide riboside, an NAD+ precursor, for effects on immunometabolism and im…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants [Phase 1]
A Phase 1 clinical trial is evaluating the safety, tolerability, and pharmacokinetics/pharmacodynamics of Surovatamig in adult participants …
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Rheumatology Patient Registry and Biorepository
This Clinical Trial Update describes a Yale University-led rheumatology patient registry and biorepository that is currently recruiting to c…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Cardiac Imaging in Systemic Disorders: the ORACLES Registry
Clinical trial registry update for the ORACLES Registry, examining cardiac imaging in systemic lupus erythematosus; the study status is NOT_…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Prognostic Factors for Fatigue in Patients With Systemic Lupus Erythematosus
This completed clinical trial identifies prognostic factors associated with fatigue in systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic (PK/PD) Profile of ACT100 in Healthy Participants.. [Phase 1]
Phase 1 trial evaluating ACT100 in healthy participants to characterize safety, tolerability, and PK/PD. The study is sponsored by Xiamen Am…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: A Phase 3 Clinical Study of MIL62 in Systemic Lupus Erythematosus [Phase 3]
A Phase 3 clinical trial of MIL62 for systemic lupus erythematosus is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: UCAR T-cell Therapy Targeting CD19/ BCMA(QT-019C) in Patients With Relapse/ Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial evaluating QT-019C UCAR T-cell therapy targeting CD19/BCMA for relapse or refractory autoimmune dise…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases [NA]
A completed clinical trial update reporting an in vitro study of interleukin-2 muteins on regulatory T cells in patients with autoimmune, al…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Study of CD19 CAR-T Therapy for Refractory SLE [Phase 1]
A Phase 1 clinical trial is evaluating a CD19 CAR-T cell therapy for refractory systemic lupus erythematosus, with recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Transition to Adulthood Through Coaching and Empowerment in Rheumatology [NA]
A completed study evaluating a coaching and empowerment program to help youths with juvenile rheumatic diseases transition to adulthood.