Systemic Lupus Erythematosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined with Immunosuppressants in the Treatment of Refractory Autoimmune Diseases [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of universal CD19 CAR-T cells (UWD-CD19) with immunosuppressants for refractory auto…
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CLINICAL_TRIALS withdrawal · 2025-02-10Clinical Trial Update: A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
Lyell Immunopharma's IMPT-514 trial in active refractory lupus nephritis and systemic lupus erythematosus has been withdrawn (Phase 1/Phase …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Study of Imvotamab in Severe Systemic Lupus Erythematosus [Phase 1]
A Phase 1 study of Imvotamab for severe systemic lupus erythematosus has been terminated.
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase exploratory study of CNCT19 anti-CD19 cell therapy for refractory systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Systemic Lupus Erythematosus Within the Framework of the Multidisciplinary Consultation [NA]
A recruiting clinical trial investigating systemic lupus erythematosus is ongoing under a multidisciplinary consultation framework, sponsore…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Evaluating Mental Health Challenges in Juvenile Lupus Erythematosus and Their Caregivers
This clinical trial aims to evaluate mental health challenges in children with juvenile systemic lupus erythematosus and assess the impact o…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Single Ascending Dose Study in Healthy Participants and Multiple Dose Study of JNJ-55920839 in Participants With Mild to Moderate Systemic Lupus Erythematosus [Phase 1]
This document reports the completion of a Phase 1 single ascending dose study in healthy participants and a multiple-dose study of JNJ-55920…
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CLINICAL_TRIALS withdrawal · 2025-02-03Clinical Trial Update: A Study of Ustekinumab in Chinese Participants With Active Systemic Lupus Erythematosus [Phase 3]
A Phase 3 clinical trial of ustekinumab in Chinese participants with active systemic lupus erythematosus has been withdrawn.
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Establishing the Salience of Type 1 Interferon Pathway Blockade in the Central Mechanisms of SLE Related Fatigue
This clinical trial update investigates the role of blocking Type I interferon signaling in the central mechanisms underlying fatigue in sys…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus
A clinical trial investigating the Systemic Immune Inflammatory Index in patients with Systemic Lupus Erythematosus and Lupus Nephritis is c…
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CLINICAL_TRIALS withdrawal · 2025-01-27Clinical Trial Update: Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases [Phase 1]
A Phase 1 pharmacokinetics study of the investigational antibody Ianalumab in Chinese participants with autoimmune diseases has been withdra…
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CLINICAL_TRIALS other · 2025-01-24Clinical Trial Update: Study of CM313(SC) Injection in Systemic Lupus Erythematosus(SLE) [Phase 2]
A Phase 2 clinical trial evaluating CM313 as a subcutaneous injection for systemic lupus erythematosus is not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: 3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erythematosus Study Protocol 2
The document describes the 3TR Study Protocol for Systemic Lupus Erythematosus, an active non-recruiting clinical trial sponsored by Univers…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: 3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erithematosus Study Protocol [Phase 3]
Phase 3 study protocol for a Systemic Lupus Erythematosus trial investigating taxonomy, treatment targets, and remission.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Addressing Disparities in Lupus Care Through an Integrated Care Management Program [NA]
Completed clinical trial from Brigham and Women's Hospital evaluating an integrated care management program to address disparities in System…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus [Phase 2]
A Phase 2 IMMA Master Protocol trial of LY3361237 in participants with at least moderately active systemic lupus erythematosus was terminate…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Biomarkers in Inflammatory Rheumatic Diseases Diagnosis
A clinical trial update from Universidade Nova de Lisboa focusing on biomarkers for diagnosing inflammatory rheumatic diseases, currently re…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State [Phase 2]
Phase 2 safety study evaluating elsubrutinib, upadacitinib, or their combination (ABBV-599) in adults with moderately to severely active sys…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases [Phase 4]
Phase 4 clinical trial is currently enrolling by invitation to evaluate herpes zoster vaccination in patients with inflammatory rheumatic di…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating LCAR-AIO for relapsed/refractory systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: A Clinical Study of CD19 CAR-T in Active Systemic Lupus Erythematosus [Phase 1, Phase 2]
Clinical trial update on CD19 CAR-T cell therapy being studied in active systemic lupus erythematosus (Phase 1/Phase 2); currently recruitin…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus
A recruiting clinical study from University Hospital, Tours investigates neonatal IgG Fc receptor expression in invariant NKT cells to under…
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CLINICAL_TRIALS other · 2025-01-08Clinical Trial Update: A Clinical Study of CD19 Universal CAR-γδT Cells in Active Systemic Lupus Erythematosus [Phase 1, Phase 2]
This clinical trial update describes an ongoing Phase 1/Phase 2 study of CD19 universal CAR-γδT cells in patients with systemic lupus erythe…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: ELEVATE - (Empower Lupus Erythematosus Patients Via Allowing RemoTe Evaluation)
The ELEVATE trial evaluating remote evaluation for systemic lupus erythematosus, sponsored by DxTerity Diagnostics, has completed.
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Effect of Vitamin D Supplement on Disease Activity in SLE [NA]
Completed clinical trial evaluating whether Vitamin D3 (Cholecalciferol) supplementation affects disease activity in Systemic Lupus Erythema…