Systemic Lupus Erythematosus

• CLINICAL_TRIALS research · 2025-05-18
  Clinical Trial Update: UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases [Phase 1]

  Phase 1 clinical trial update for UCAR T-cell therapy targeting CD19/BCMA in relapse/refractory autoimmune diseases. The study includes seve…

• CLINICAL_TRIALS trial_result · 2025-05-14
  Clinical Trial Update: Efficacy and Safety of Belimumab in SLE Patients [Phase 4]

  A Phase 4 trial evaluating the efficacy and safety of belimumab in systemic lupus erythematosus has completed.

• CLINICAL_TRIALS research · 2025-05-14
  Clinical Trial Update: Early Clinical Study of UTAA91 Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases [EARLY_Phase 1]

  An early Phase 1 clinical trial is evaluating UTAA91 Injection for relapsed/refractory autoimmune diseases. The study is not yet recruiting …

• CLINICAL_TRIALS research · 2025-05-14
  Clinical Trial Update: Efficacy and Safety of Low-dose IL-2 in SLE Patients With CMV Viremia [Phase 2]

  Phase 2 clinical trial evaluating the efficacy and safety of low-dose interleukin-2 in patients with systemic lupus erythematosus and cytome…

• CLINICAL_TRIALS trial_result · 2025-05-13
  Clinical Trial Update: A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus [Phase 1]

  A Phase 1 clinical study evaluating YTS109 cells in relapsed/refractory systemic lupus erythematosus, including lupus nephritis and immune t…

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• CLINICAL_TRIALS research · 2025-05-13
  Clinical Trial Update: Retrospective Medical Chart Review Study to Describe the Experience of SLE Patients Treated With Anifrolumab in the Early Access Programs.

  Retrospective chart review describing the experience of systemic lupus erythematosus patients treated with anifrolumab in early access progr…

• CLINICAL_TRIALS trial_result · 2025-05-07
  Clinical Trial Update: Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)

  Trial update reporting the termination of a Johns Hopkins University study evaluating kidney MRI in patients with systemic lupus erythematos…

• CLINICAL_TRIALS research · 2025-05-01
  Clinical Trial Update: UCAR T-cell Therapy Targeting CD19/BCMA in Patients With r/r Systemic Lupus Erythematosus [EARLY_Phase 1]

  An early-phase 1 clinical trial from Zhejiang University evaluating UCAR T-cell therapy targeting CD19/BCMA in patients with relapsed/refrac…

• CLINICAL_TRIALS trial_result · 2025-04-29
  Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered Mosunetuzumab to Participants With Systemic Lupus Erythematosus [Phase 1]

  A Phase 1 clinical trial evaluating subcutaneously administered mosunetuzumab in systemic lupus erythematosus has completed its assessment o…

• CLINICAL_TRIALS research · 2025-04-29
  Clinical Trial Update: An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus [EARLY_Phase 1]

  This is an early-phase 1 exploratory clinical study evaluating anti-CD19 CAR NK cells for systemic lupus erythematosus and it is currently r…

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE [Phase 1]

  Phase 1 clinical trial evaluating BCMA/CD70 CAR-T therapy for refractory childhood-onset systemic lupus erythematosus (cSLE) is currently re…

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: An Open-label Study of GB261 in Refractory Seropositive Systemic Lupus Erythematosus [Phase 1]

  An open-label Phase 1 trial of GB261 for refractory seropositive systemic lupus erythematosus is currently not recruiting.

• CLINICAL_TRIALS trial_result · 2025-04-24
  Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus [Phase 3]

  Phase 3 trial update reporting efficacy and safety results for Dapirolizumab Pegol in moderately to severely active Systemic Lupus Erythemat…

• CLINICAL_TRIALS withdrawal · 2025-04-24
  Clinical Trial Update: A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Systemic Lupus Erythematosus [Phase 1]

  A Phase 1 study evaluating the safety and preliminary efficacy of ATA3219 in systemic lupus erythematosus and lupus nephritis has been withd…

• CLINICAL_TRIALS trial_result · 2025-04-20
  Clinical Trial Update: Hematological Manifestations in Systemic Lupus Erythematosus Patients

  This clinical trial update reports on hematological manifestations in patients with Systemic Lupus Erythematosus and notes that the study ha…

• CLINICAL_TRIALS trial_result · 2025-04-18
  Clinical Trial Update: Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis [Phase 1]

  Phase 1 study of EQ001 (Itolizumab) in systemic lupus erythematosus with or without active proliferative nephritis has completed and posted …

• CLINICAL_TRIALS trial_result · 2025-04-17
  Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of Single Doses of HC022 in Healthy Subjects. [Phase 1]

  Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of single doses of HC022 in healthy subjects, with systemic lupus er…

• CLINICAL_TRIALS trial_result · 2025-04-16
  Clinical Trial Update: Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients [Phase 4]

  Phase 4 trial update assessing cardio-renal effects of SGLT2 inhibitors in lupus nephritis patients; results have been posted.

• CLINICAL_TRIALS other · 2025-04-13
  Clinical Trial Update: Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)

  This clinical trial update indicates that a study on predictors of pregnancy outcomes in systemic lupus erythematosus and antiphospholipid s…

• CLINICAL_TRIALS research · 2025-04-11
  Clinical Trial Update: Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases [Phase 1, Phase 2]

  Clinical trial update for anti-CD19 CAR T-cell therapy being explored in refractory systemic autoimmune diseases, including systemic lupus e…

• CLINICAL_TRIALS research · 2025-04-09
  Clinical Trial Update: Chinese Rheumatism Biobank(CRB)

  This clinical trial update notes that the NCT06887517 study by the Chinese SLE Treatment And Research Group is currently recruiting for syst…

• CLINICAL_TRIALS research · 2025-04-09
  Clinical Trial Update: Physical Activity in Patients With Systemic Lupus Erythematosus

  A clinical trial evaluating physical activity in patients with systemic lupus erythematosus is listed, and it is currently not recruiting.

• CLINICAL_TRIALS research · 2025-04-08
  Clinical Trial Update: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Lupus [Phase 1]

  Phase 1 clinical trial update evaluating the safety of intravenously infused allogeneic umbilical cord-derived mesenchymal stem cells for sy…

• CLINICAL_TRIALS research · 2025-04-06
  Clinical Trial Update: Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases [NA]

  An active, not-recruiting clinical trial at Northwestern University is studying vaccine hesitancy among Black/African American patients with…

• CLINICAL_TRIALS trial_result · 2025-04-04
  Clinical Trial Update: A Study of DS-7011a in Patients With Systemic Lupus Erythematosus [Phase 1, Phase 2]

  A completed Phase 1/2 clinical trial evaluating DS-7011a in patients with systemic lupus erythematosus.