Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus [Phase 2]
Phase 2 clinical trial evaluating distinct immunophenotypes to validate and optimize immunotherapy strategies for systemic lupus erythematos…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Type 1 Interferon Induced Changes to Exercise Adaptations in Systemic Lupus Erythematosus Patients [NA]
This clinical trial update reports a completed study examining the effects of Type I Interferon on exercise adaptations in patients with sys…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Safety Study of Two Vaccine Strategies in Patients With Systemic Lupus Erythematosus [Phase 2, Phase 3]
Completed Phase 2/Phase 3 safety study evaluating two vaccine strategies in patients with systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Does Belimumab Modify the Natural History of SLE? A Propensity Score-matched, Real-world Study
An ongoing real-world study using propensity score matching to assess whether belimumab alters the natural history of systemic lupus erythem…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation
A recruiting clinical trial in France aims to develop a diagnosis, prognosis, and therapeutic decision-support tool for autoimmune and infla…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Associating Gastric Infection With Autoimmune Flare Severity in an Egyptians
Assiut University is updating a clinical trial to evaluate whether Helicobacter pylori gastric infection influences the severity of autoimmu…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Systemic Lupus Erythematosus and Accelerated Aging [NA]
A clinical trial sponsored by University Hospital, Bordeaux is investigating systemic lupus erythematosus with accelerated aging and is curr…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases [NA]
An active but not recruiting clinical trial is testing UCAR T-cell therapy targeting CD19/BCMA in patients with systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Association of Serum Interleukin-33 Levels With Clinical Manifestations in Systemic Lupus Erythematosus
A clinical trial investigating the association between serum interleukin-33 levels and clinical manifestations in systemic lupus erythematos…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy
This clinical trial update describes ongoing research in safety and efficacy assessment for rheumatologic diseases and related conditions, w…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Study of Anti-Malarials in Incomplete Lupus Erythematosus [Phase 2]
Phase 2 trial evaluating anti-malarial therapy in incomplete lupus erythematosus has completed with results posted.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Observational Study Investigating Demographic and Clinical Characteristics of SLE Patients in Egypt
An observational study sponsored by AstraZeneca aims to characterize demographic and clinical features of systemic lupus erythematosus patie…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: LUPUS-BEST - Treat-to-target in Systemic Lupus Erythematosus [NA]
The LUPUS-BEST trial evaluating a treat-to-target strategy in systemic lupus erythematosus is currently recruiting at Heinrich-Heine Univers…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders [Phase 2]
This Phase 2 trial evaluating a COVID-19 booster vaccine in autoimmune-disease non-responders was terminated, with results posted on 2025-08…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Safety, Pharmacokinetics, Immunogenicity BCD-256-1 and Divozilimab in Subjects With Systemic Lupus Erythematosus [Phase 1]
Phase 1 clinical trial update evaluating safety, pharmacokinetics, and immunogenicity of BCD-256-1 and Divozilimab in adults with systemic l…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: OMERACT SLE Delphi
An update on the OMERACT SLE Delphi study to reach consensus on outcome measures for systemic lupus erythematosus; the study is not yet recr…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: The Diagnostic Utility of T Immunoglobulin G and T Immunoglobulin M Biomarkers in Patients With Systemic Lupus Erythematosus Disease : Associations With Disease Activity and Damage [NA]
A clinical trial exploring the utility of T immunoglobulin G and T immunoglobulin M biomarkers in systemic lupus erythematosus and their ass…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study evaluating universal CD19-targeting CAR-γδT cells for refractory autoimmune diseases,…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Peer Approaches to Lupus Self-management [NA]
A clinical trial evaluating peer-based approaches to self-management for systemic lupus erythematosus. The study is currently active but not…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: The Relation of Albumin/Globulin Ratio and Platelet/Albumin Ratio to Lupus Nephritis
A clinical trial evaluating whether albumin/globulin ratio and platelet/albumin ratio serve as biomarkers in Lupus Nephritis; the study is n…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Direct to Patient Minimal Risk Biospecimen and Data Collection Research
A direct-to-patient, minimal-risk biospecimen and data collection study sponsored by Joined Bio, currently NOT_YET_RECRUITING, enrolling bot…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: IM19 CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus (SLE) [NA]
This clinical trial update notes that IM19 CAR-T cell therapy is recruiting for patients with refractory Systemic Lupus Erythematosus.
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: ALPN-101 (Acazicolcept) in Systemic Lupus Erythematosus [Phase 2]
Phase 2 trial of ALPN-101 (Acazicolcept) for systemic lupus erythematosus has completed and results have been posted.
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Anifrolumab Pregnancy Study
This document reports a planned clinical trial to evaluate pregnancy outcomes in people with systemic lupus erythematosus treated with anifr…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis [Phase 2]
Phase 2 trial update for obe-cel in patients with severe, refractory systemic lupus erythematosus and active lupus nephritis; the study is c…