Systemic Inflammatory Response Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Cerebral Autoregulation in Non Neurological Critical Patients.
A study investigating cerebral autoregulation in non-neurological critically ill patients has been terminated, according to the clinical tri…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG) [Phase 2]
Phase 2 clinical trial update evaluating immunomodulation with EA-230 following on-pump coronary artery bypass grafting for systemic inflamm…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: Genotypes and Phenotypes in Pediatric SIRS and Sepsis
This entry notes the completed clinical trial conducted at Seattle Children's Hospital examining genotypes and phenotypes in pediatric Syste…
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS
The Ward Study evaluating SeptiCyte Lab to distinguish infection-positive from infection-negative SIRS has been terminated.
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA [Phase 3]
Phase 3 prospective validation study of albumin kinetics using tracer 123 I-HSA has completed.
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response [NA]
This completed trial evaluated corticosteroid prophylaxis for reducing the systemic inflammatory response associated with cardiopulmonary by…
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU
A completed clinical trial evaluates biomarkers to discriminate systemic inflammatory response syndrome from bacterial sepsis in ICU patient…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Evaluation of Intestinal Brush Border Enzyme Function in Critically Ill Patients [NA]
A completed clinical trial evaluating intestinal brush border enzyme function in critically ill patients, including those with septic shock …
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CLINICAL_TRIALS trial_result · 2017-08-25Clinical Trial Update: Effect of APC and Epo on the Inflammatory Response During Sepsis
A completed clinical trial evaluated the effects of activated protein C and erythropoietin on the inflammatory response in sepsis.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients [Phase 4]
Phase 4 pharmacokinetic study comparing two high-dose regimens of intravenous vitamin C in critically ill patients, including those with sep…
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: Effects of IV Chloride Content on Outcomes
This clinical trial update examines how intravenous chloride content in balanced fluids impacts outcomes in systemic inflammatory response s…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Efficacy of Macrolide Immunomodulation in Severe Sepsis. [Phase 2]
A Phase 2 clinical trial evaluating macrolide-based immunomodulation in severe sepsis was terminated. The update references efficacy assessm…
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: The Importance of Albumin Infusion Rate for Plasma Volume Expansion Following Major Abdominal Surgery [Phase 4]
This Phase 4 study update investigates how the rate of albumin infusion affects plasma volume expansion after major abdominal surgery.
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: IMproved PREdiction of Severe Sepsis in the Emergency Department
Completed clinical trial evaluating improved prediction of severe sepsis in the emergency department, sponsored by Axis Shield Diagnostics L…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal [Phase 4]
Phase 4 clinical trial update evaluating CytoSorb for inflammatory cytokine removal in acute pancreatitis and systemic inflammatory response…
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Accuracy of Pulse Pressure Variations Measured by a Non Invasive Digital Device to Predict Fluid Responsiveness [NA]
Terminated clinical trial evaluating the accuracy of a non-invasive digital device measuring pulse pressure variations to predict fluid resp…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Towards a High-fat Feeding Intervention Study: Identification of Markers for Inflammation and Organ Damage
A completed clinical trial evaluating a high-fat feeding intervention to identify biomarkers of inflammation and organ damage in patients wi…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Studying Complement Inhibition in Complex Cardiac Surgery [Phase 2]
A Phase 2 trial evaluating complement inhibition with vilobelimab in patients undergoing complex cardiac surgery has completed.
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CLINICAL_TRIALS research · 2017-02-06Clinical Trial Update: Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients [NA]
This clinical trial update investigates whether vitamin D supplementation affects hepcidin levels and transfusion requirements in surgical a…
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CLINICAL_TRIALS trial_result · 2017-01-25Clinical Trial Update: Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics [Phase 4]
A Phase 4 trial update investigating how age, sepsis, and SLCO1A2 genetics affect rocuronium pharmacokinetics in septic conditions; the stud…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock
A clinical trial update reporting results of NT-proBNP assessment in ICU patients with shock after surgery or trauma, including inflammatory…
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CLINICAL_TRIALS trial_result · 2017-01-02Clinical Trial Update: PPV to Guide Fluid Management in the PICU [NA]
A completed UNC study evaluated using PPV to guide fluid management in pediatric ICU patients with sepsis/SIRS; results were posted in Janua…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
Clinical Trial Update: INFLACOR investigates clinical and genetic predictors of inflammation-related complications after heart surgery. The …
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CLINICAL_TRIALS trial_result · 2016-10-06Clinical Trial Update: Effect of Education on Resident Physician Knowledge of Sepsis [NA]
A completed clinical trial evaluating whether an educational intervention improves resident physicians' knowledge of sepsis and systemic inf…
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Utility of Presepsin in Distinguishing Between Sepsis and SIRS
Completed clinical trial evaluating presepsin for distinguishing sepsis from SIRS; results posted in 2016.