Symptomatic Irreversible Pulpitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-25Clinical Trial Results: Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain [Phase 2, Phase 3]
Phase 2/3 trial evaluating preoperative tramadol and naproxen sodium for reduction of postoperative pain in patients with symptomatic irreve…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain [NA]
This clinical trial update reports on the effects of three different medications on anesthetic success and postoperative pain in patients wi…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Postoperative Pain After Single-Cone Root Canal Obturation Using Three Sealers [NA]
Clinical trial update on postoperative pain after single-cone root canal obturation using three sealers in patients with symptomatic irrever…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Tobradex as Intracanal Medicament [NA]
Completed clinical trial evaluating Tobradex as an intracanal medicament for symptomatic irreversible pulpitis and postoperative endodontic …
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: The Effect of Commercial and Medical Grade Sodium Hypochlorite on Post Endodontic Pain [NA]
A completed clinical trial from Cairo University evaluating the effect of commercial and medical-grade sodium hypochlorite on post-endodonti…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis [NA]
This completed clinical trial evaluated the effect of different cryotherapy modalities on postoperative pain in patients with symptomatic ir…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Measure Postoperative Pain and Bacterial Reduction After Different Final Irrigation Protocols. [NA]
A clinical trial from Future University in Egypt is evaluating postoperative pain and bacterial reduction with different final irrigation pr…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Comparative Evaluation of Postoperative Pain and Clinical Success [NA]
A completed clinical trial at Ege University evaluated postoperative pain and clinical success in symptomatic irreversible pulpitis.
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Effect of Dental Anxiety on Mandibular Anesthesia Success [NA]
A completed clinical trial assessing whether dental anxiety influences the success rate of mandibular anesthesia in patients with symptomati…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Evaluation of Success of Complete Pulpotomy With Biodentine on Mature Permanent Single Rooted Teeth With Symptomatic Irreversible Pulpitis [NA]
This clinical trial update reports the completion of a study evaluating the success of complete pulpotomy using Biodentine in mature permane…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment [Phase 4]
Phase 4 trial evaluated whether post-operative anesthetics influence post-operative pain in patients receiving endodontic treatment. Results…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Combination of Buffered Anesthetic to Treat Mandibular Molars [Phase 4]
A Phase 4 trial evaluating a buffered anesthetic combination for treating symptomatic irreversible pulpitis in mandibular molars was termina…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial. [Phase 1]
A Phase 1 randomized trial evaluating post-operative pain and IL-8 expression using ketorolac tromethamine versus cryoirrigation as the fina…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluated whether preoperative tramadol and naproxen sodium reduce postoperative pain in patients with symptomati…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis [Phase 4]
A Phase 4 trial comparing buffered and unbuffered local anesthesia in mandibular molars with symptomatic irreversible pulpitis has completed…
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CLINICAL_TRIALS trial_result · 2023-09-07Clinical Trial Update: Role of Propolis Endodontic Irrigant on Post-Operative Pain [Phase 3]
Phase 3 trial update evaluating propolis endodontic irrigant for post-operative pain in symptomatic irreversible pulpitis, completed.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator [NA]
A completed clinical trial comparing postoperative pain and healing in teeth treated with GentleWave vs EndoActivator.
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CLINICAL_TRIALS trial_result · 2022-10-31Clinical Trial Update: The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste [Phase 4]
Phase 4 trial comparing single antibiotic paste nitrofurantoin to double antibiotic paste for pain related to symptomatic irreversible pulpi…
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block. [Phase 4]
Phase 4 clinical trial comparing preoperative analgesics for efficacy of inferior alveolar nerve block in symptomatic irreversible pulpitis;…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: Postoperative Pain Intensity After Pulpotomy [Phase 4]
A Phase 4 clinical trial evaluating postoperative pain intensity after pulpotomy in patients with symptomatic irreversible pulpitis has comp…
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CLINICAL_TRIALS trial_result · 2020-10-30Clinical Trial Update: Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression [Phase 4]
Phase 4 clinical trial comparing diclofenac potassium to prednisolone for post-endodontic pain and pulpal IL-8 expression in symptomatic irr…
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain [Phase 2]
Phase 2 trial updating efficacy of an anti-inflammatory block injection for mandibular dental pain due to symptomatic irreversible pulpitis …
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CLINICAL_TRIALS trial_result · 2018-11-01Clinical Trial Update: Anesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine [Phase 2, Phase 3]
A Phase 2/Phase 3 trial comparing the anesthetic efficacy of 2% mepivacaine versus 4% articaine in symptomatic irreversible pulpitis is in p…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: The Effect of Central Sensitization on Assessment Capacity of Patients
This clinical trial update reports on the completion of a study assessing how central sensitization affects patients' ability to be assessed…
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: Pretreatment Aceclofenac Effect on Pain and Analgesic Intake After Endodontic Treatment [Phase 2, Phase 3]
This clinical trial update reports completion of Phase 2 and Phase 3 studies evaluating whether pretreatment with aceclofenac reduces post-e…