Surgical Site Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-02-26Clinical Trial Update: Individualized Perioperative Open-lung Ventilatory Strategy With High Versus Conventional Inspiratory Oxygen Fraction (iPROVE-O2). [NA]
The iPROVE-O2 trial evaluates a perioperative open-lung ventilation strategy using high versus conventional inspired oxygen fraction, with h…
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CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: Effect of Vitamin E-containing Dressing on Surgical Site Infection in Colorectal Surgery [Phase 3]
Phase 3 clinical trial evaluating a vitamin E–containing dressing for reducing surgical site infection after colorectal surgery is in an unk…
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CLINICAL_TRIALS research · 2017-12-08Clinical Trial Update: RCT on NPWT for Incisions Following Major Lower-limb Amputation to Reduce Surgical Site Infection [NA]
An randomized controlled trial is evaluating whether negative pressure wound therapy (NPWT) on amputation incisions reduces surgical site in…
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CLINICAL_TRIALS research · 2017-10-11Clinical Trial Update: Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery
This clinical trial update investigates risk factors for Staphylococcus aureus surgical site infections in patients undergoing orthopedic an…
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FDA approval · 2017-09-12FDA Approved: CHLORAPREP ONE-STEP — Supplemental Application (CareFusion 213, LLC)
The FDA approved a supplemental application for CHLORAPREP ONE-STEP, a chlorhexidine gluconate and isopropyl alcohol antiseptic by CareFusio…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Cubicin(R) for Complicated Post-surgical Wound Infections [Phase 4]
The Phase 4 trial of Cubicin for complicated post-surgical wound infections was terminated.
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection [NA]
A completed trial evaluated the effectiveness and safety of azithromycin-based extended-spectrum prophylaxis to prevent post-cesarean infect…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Pilot Clinical Evaluation to Characterize in Vivo Effects of Topically Applied ZuraPrep & ZuraPrep Vehicle [Phase 3]
A Phase 3 pilot clinical evaluation of topically applied ZuraPrep and its vehicle for effects related to surgical site infection has complet…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Topical Silver for Prevention of Wound Infection After Cesarean Delivery [NA]
Terminated clinical trial evaluating topical silver to prevent wound infection after cesarean delivery; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Effect of Standard Normothermia Protocol On Surgical Site Infections [NA]
This update reports the completion and posting of results for a clinical trial evaluating whether a standard normothermia protocol reduces s…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Silver Impregnated Dressings to Reduce Wound Complications in Obese Patients at Cesarean Section [Phase 4]
A Phase 4 trial tested silver-impregnated dressings to reduce wound complications in obese women undergoing cesarean section; the study was …
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP) [NA]
This clinical trial completed an evaluation of preoperative scrubbing with chlorhexidine digluconate and parachlorometaxylenol (ECP) for pre…
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Impact of Structured Communication in the OR on Surgical Site Infections: Prospective Observational Clinical Trial
A completed prospective observational trial evaluated whether structured in-OR communication, including short intraoperative briefings, infl…
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CLINICAL_TRIALS other · 2017-02-13Clinical Trial Update: Prophylactic Post-Cesarean Incisional Negative-pressure Wound Therapy in Morbidly Obese Patients [NA]
Clinical trial update about prophylactic post-cesarean incisional negative-pressure wound therapy in morbidly obese patients; trial status i…
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section [NA]
A completed clinical trial evaluating incisional negative pressure wound therapy to prevent postoperative surgical site infections after ces…
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CLINICAL_TRIALS research · 2016-12-22Clinical Trial Update: Wound Infections Following Implant Removal [Phase 4]
Phase 4 study evaluating surgical site infections after implant removal has completed.
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: Study of Chlorhexidine Gluconate as a Preoperative Antisepsis [Phase 3]
A Phase 3 study evaluating chlorhexidine gluconate for preoperative antisepsis to prevent surgical site infections has completed.
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Prophylactic Negative Pressure Dressings for Closed Laparotomy Wounds - A Randomised, Controlled, Open Label Trial [Phase 2]
A Phase 2 randomized, open-label trial evaluated prophylactic negative pressure dressings to prevent surgical site infection after closed la…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: Intervention for Postpartum Infections Following Caesarean Section [NA]
This clinical trial update reports the completion of a study evaluating an intervention to prevent postpartum infections after cesarean sect…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: The Use of a Silver Containing Dressing (Acticoat) on Wound Complication Rates Post Elective Cesarean Section [NA]
This completed trial evaluated the effect of a silver-containing dressing (Acticoat) on wound complication rates after elective cesarean sec…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery [NA]
This completed clinical trial evaluated using a collagen-Gentamicin local application with extra sternum fixation to prevent sternal wound i…
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial [NA]
Clinical trial update describing completion of a randomized study comparing bacterial colonization with iodophor-impregnated adhesive drapes…
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Randomized Controlled Trial to Evaluate the Optimal Timing of Surgical Antimicrobial Prophylaxis [Phase 4]
A Phase 4 randomized trial evaluated the optimal timing of surgical antimicrobial prophylaxis to prevent surgical site infections, and the s…
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: The Effect of Timing of Removal of Wound Dressing on Surgical Site Infection Rate After Cesarean Delivery [NA]
A completed clinical trial investigated whether the timing of removing a wound dressing after cesarean delivery affects the rate of surgical…
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery [Phase 3]
Phase 3 trial update reporting the pharmacokinetics of daptomycin during cardiopulmonary bypass surgery; results were posted in 2016.