Surgical Site Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Betadine Irrigation in Cesarean Section [NA]
A clinical trial evaluating povidone-iodine irrigation during cesarean section has completed.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ [Phase 2]
Phase 2 efficacy study evaluating antimicrobial effectiveness of ZuraPrep for surgical site infections was terminated.
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055) [Phase 2]
The Phase 2 efficacy study evaluating ZuraPrep (ZX-ZP-0055) for preventing surgical site infections has been completed.
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: The Use of Diluted Povidone Iodine Irrigation in Spine Surgery [Phase 2]
Phase 2 trial evaluating diluted povidone-iodine irrigation to prevent surgical site infections in spine surgery has been terminated.
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity [NA]
A controlled clinical trial evaluated whether supplemental oxygen reduces post-cesarean infectious morbidity; the study is completed.
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains
Clinical trial update reporting completion of a study comparing antibiotic protocols in spine surgery patients with postoperative drains.
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CLINICAL_TRIALS research · 2016-05-19Clinical Trial Update: LAW Trial -The Impact of Local Anesthetics Infiltration in Surgical Wound of Gastrointestinal Procedures [NA]
Clinical trial update on the LAW Trial evaluating the impact of local anesthetic infiltration in gastrointestinal surgical wounds, with outc…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Recolonization Following Preoperative Disinfection Plastic Adhesive Drapes [Phase 3]
Phase 3 clinical trial assessing recolonization after using preoperative disinfection with plastic adhesive drapes for preventing surgical s…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Single Dose Ceftriaxone and Metronidazole Versus Multiple Doses for Antibiotic Prophylaxis at Elective Cesarean Section. [Phase 4]
This Phase 4 trial conducted at Makerere University compared single-dose ceftriaxone plus metronidazole versus traditional multi-dose antibi…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Efficacy Study of Delayed Primary Closure to Reduce Rate of Wound Infection in Complicated Appendicitis [Phase 3]
A Phase 3 trial evaluating delayed primary closure to reduce wound infection after complicated appendicitis has completed.
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CLINICAL_TRIALS research · 2016-03-31Clinical Trial Update: Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications
Massachusetts General Hospital is evaluating whether intra-operative inspiratory oxygen fraction influences postoperative respiratory compli…
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors [NA]
The trial compared the Alexis O surgical retractor with standard metal retractors in cesarean sections to evaluate surgical site infection o…
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CLINICAL_TRIALS trial_result · 2016-01-07Clinical Trial Update: Comparison of Surgical Site Infection Rate Between Primary, Delayed Primary and Vacuum Assisted Closures. [NA]
This completed clinical trial compared surgical site infection rates across primary, delayed primary, and vacuum-assisted closures for surgi…
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: PHMB-based Antiseptic Use in Full-thickness Surgical Wounds [NA]
The trial update notes completion of a clinical study evaluating a polyhexamethylene biguanide (PHMB)–based antiseptic for preventing infect…
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CLINICAL_TRIALS research · 2015-12-02Clinical Trial Update: The AVATAR Trial: Applying VAcuum To Accomplish Reduced Wound Infections [NA]
The AVATAR trial evaluated vacuum-assisted therapy to reduce surgical site infections after laparoscopy, but the study was terminated.
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Increased Microcirculation for Preventing Postoperative Wound Infections in Patients Undergoing Reduction Mammoplasty [Phase 4]
Phase 4 clinical trial update investigating strategies to increase microcirculation to prevent postoperative wound infections after reductio…
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CLINICAL_TRIALS research · 2015-12-02Clinical Trial Update: The Use of Ceftaroline as Surgical Prophylaxis in Surgery With Risk of MRSA Infection [Phase 4]
An update on a Phase 4 clinical trial evaluating ceftaroline as surgical prophylaxis for MRSA-risk surgeries; current status is unknown.
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FDA approval · 2015-11-12FDA Approved: 3M AVAGARD — Supplemental Application (Solventum US LLC)
The FDA approved a supplemental application for 3M AVAGARD (Chlorhexidine Gluconate and Alcohol) from Solventum US LLC.
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Medixair® System on Surgical Site Infection in Cardiac Patients [NA]
Completed clinical trial update evaluating the Medixair System for preventing surgical site infections in cardiac surgery patients.
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CLINICAL_TRIALS research · 2015-07-31Clinical Trial Update: Negative Pressure Wound Therapy for the Prevention of Surgical Site Infection Following Lower Limb Revascularization [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating negative pressure wound therapy to prevent surgical site infection after lower limb revascularization.
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CLINICAL_TRIALS research · 2015-07-21Clinical Trial Update: Tumescent Antibiotic Delivery for Prevention of Surgical Site Infection [Phase 2, Phase 3]
This document provides an update on an ongoing Phase 2/Phase 3 trial evaluating tumescent antibiotic delivery to prevent surgical site infec…
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CLINICAL_TRIALS trial_result · 2015-06-25Clinical Trial Update: Antibiotic Prophylaxis for Elective Cesarean Section [Phase 3]
Phase 3 clinical trial evaluating antibiotic prophylaxis to prevent surgical site infection after elective cesarean section has completed.
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FDA label_change · 2015-06-08FDA Approved: 3M DURAPREP SURGICAL — Supplemental Application (Solventum US LLC)
FDA approved a labeling supplement for 3M Duraprep Surgical (iodine povacrylex and isopropyl alcohol) submitted by Solventum US LLC.
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: Study to Evaluate DACC Dressings for the Prevention of Surgical Site Infections in Women Undergoing Caesarean Section. [NA]
A completed clinical trial evaluating DACC dressings for the prevention of surgical site infections in women undergoing cesarean section.
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: Acid Base and Electrolytes Patterns in Drains Operational Wounds and Its Relation to Complications
This clinical trial update examines acid-base and electrolyte patterns in drainage from surgical wounds and how these patterns relate to pos…