Stiff-person Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study Investigating Intravenous Human Normal Immune Globulin 10% in Adults With Stiff Person Syndrome [Phase 3]
Phase 3 trial investigating intravenous human normal immunoglobulin 10% for adults with Stiff Person Syndrome is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease [Phase 1]
Phase 1 trial update for Prulacabtagene Leucel (Prula-cel) in autoimmune diseases, with enrollment by invitation ongoing across indications …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases [Phase 2]
Phase 2 clinical trial investigating autologous stem cell transplant for neurologic autoimmune diseases is currently active but not recruiti…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
A long-term follow-up study for participants previously treated with KYV-101; recruitment is ongoing across multiple autoimmune diseases.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Evaluating Spinal Cord Stimulation for Stiff Person Syndrome [NA]
The clinical trial evaluating spinal cord stimulation for Stiff-person syndrome has completed.
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Study of C-CAR168 in the Treatment of Central Nervous System Autoimmune Diseases Refractory to Standard Therapy [Phase 1]
This is a Phase 1 clinical trial evaluating the safety and feasibility of C-CAR168 for CNS autoimmune diseases. The study is not yet recruit…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: KYSA-8: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Treatment Refractory Stiff Person Syndrome [Phase 2]
This clinical trial update describes KYSA-8, an anti-CD19 CAR T-cell therapy from Kyverna Therapeutics, being studied for treatment-refracto…
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CLINICAL_TRIALS other · 2025-10-06Clinical Trial Update: Extracorporeal Photopheresis (ECP) in the Treatment of Stiff Person Syndrome (OPTION Study) [EARLY_Phase 1]
This update describes an early-phase Phase 1 clinical trial (OPTION Study) evaluating Extracorporeal Photopheresis for stiff-person syndrome…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Efgartigimod for Stiff Person Syndrome (ESPS) [Phase 2]
A Phase 2 trial assessing efgartigimod for stiff-person syndrome is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Biomarkers in Autoimmune Disease of Nervous System
A Tongji Hospital clinical trial is recruiting to study biomarkers in autoimmune diseases of the nervous system, including Neuromyelitis Opt…
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Stem Cell Transplantation for Stiff Person Syndrome (SPS) [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating stem cell transplantation for Stiff-Person Syndrome was terminated; results were posted in 2021.
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CLINICAL_TRIALS withdrawal · 2019-06-13Clinical Trial Update: Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome [Phase 3]
A Phase 3 randomized placebo-controlled trial of IVIg in glycine receptor antibody–positive Stiff-Person Syndrome was withdrawn.
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Cause, Development, and Progression of Stiff-Person Syndrome
An update on the cause, development, and progression of Stiff-Person Syndrome from a NINDS-sponsored clinical trial (NCT00030940). The study…
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CLINICAL_TRIALS trial_result · 2011-08-31Clinical Trial Update: Rituximab to Treat Stiff Person Syndrome [Phase 2]
A Phase 2 trial evaluating rituximab for Stiff Person Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2006-07-14Clinical Trial Update: Intravenous Immunoglobulin (IVIg) for the Treatment of Stiff-Man Syndrome (SMS) [Phase 1]
A Phase 1 study evaluated intravenous immunoglobulin (IVIg) for the treatment of stiff-person syndrome. The trial has completed.