Steroid-refractory Graft-versus-host Disease
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CLINICAL_TRIALS other · 2025-11-13Clinical Trial Update: Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation [Phase 1]
The document reports that a Phase 1 study evaluating allogeneic CD6-CAR T regulatory cells for chronic graft-versus-host disease after allog…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease [Phase 1]
A Phase 1 clinical trial update on Leflunomide for steroid-dependent chronic graft-versus-host disease. The study is currently active but no…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD [Phase 1, Phase 2]
Phase 1/2 trial of the BET inhibitor PLX51107 for steroid-refractory acute graft-versus-host disease was terminated; results have been poste…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: MaaT013 As Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients [Phase 3]
Phase 3 clinical trial evaluating MaaT013 as salvage therapy for ruxolitinib-refractory gastrointestinal acute graft-versus-host disease; th…
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
Phase 2 trial evaluating decidual stromal cells for treatment of steroid-refractory graft-versus-host disease after allogeneic stem cell tra…
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