Squamous Cell Carcinoma of the Lung
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Comparison of Serplulimab Versus Nivolumab in Neoadjuvant Therapy for Resectable Stage II-IIIA Squamous NSCLC [Phase 2]
A Phase 2 neoadjuvant trial is comparing Serplulimab to Nivolumab in resectable stage II-IIIA squamous non-small cell lung cancer, and recru…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Clinical Study of the Therapeutic Effectiveness of In-silico-Designed, Machine Learning Inspired, and Quantum-molecularly Coupled Personalized Neoantigenic Vaccines Microlyvaq™ in Patients With Advanced Non-small Cell Lung Cancer [EARLY_Phase 1]
Early Phase 1 update on Microlyvaq™, a personalized neoantigenic vaccine designed with in-silico, machine-learning, and quantum-molecular co…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors [Phase 1, Phase 2]
Clinical trial update for BOXR1030 T Cells shows a Phase 1/2 study in GPC3-positive solid tumors, including hepatocellular carcinoma and add…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer [Phase 2]
This update reports results from a Phase 2 study evaluating PD-L1 positive non-small cell lung cancer treated with immunotherapy as monother…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update reports results from evaluating the combination of sirolimus and auranofin in patients with advanced…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Comparison of Longer-term (5 Year+) Outcomes (Survival) of Smokers, Ex-smokers, Never Smoker and Quitters
Clinical trial update reporting longer-term (5+ year) survival outcomes. It compares smokers, ex-smokers, never smokers, and quitters in pat…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands [Phase 1]
Phase 1 clinical trial update of LGK974, a Wnt pathway inhibitor, in malignancies dependent on Wnt ligands; the study included several cance…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors. [Phase 1]
Pfizer's Phase 1 study of PF-06940434 in advanced or metastatic solid tumors has been terminated. The trial enrolled several solid tumor typ…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial of sapanisertib in relapsed/refractory squamous non-small cell lung cancer (including NFE2L2-mutant and wild-type) has been te…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Bispecific PSMAxCD3 Antibody CC-1 in Patients With Squamous Cell Carcinoma of the Lung [Phase 1, Phase 2]
A phase 1/2 trial of the bispecific PSMAxCD3 antibody CC-1 in squamous cell carcinoma of the lung has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: A Study of Bemarituzumab Monotherapy and Combination With Other Anti-cancer Therapy in SqNSCLC With FGFR2b Overexpression (FORTITUDE-201) [Phase 1]
Fortitude-201 (bemarituzumab) is a Phase 1 trial evaluating bemarituzumab alone or in combination with other anti-cancer therapies in FGFR2b…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008) [Phase 3]
A Phase 3 study evaluating pembrolizumab with or without maintenance olaparib as first-line treatment in metastatic squamous non-small cell …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Real-World Effectiveness of Afatinib (Gilotrif) Following Immunotherapy in the Treatment of Metastatic, Squamous Cell Carcinoma of the Lung: A Multi-Site Retrospective Chart Review Study in the U.S.
A multi-site retrospective chart review assessing real-world effectiveness of afatinib following immunotherapy in patients with metastatic s…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Study of ADXS-503 With or Without Pembro in Subjects With Metastatic Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Clinical trial update reports completion and posted results for ADXS-503 with or without pembrolizumab in metastatic non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Tipifarnib in Advanced Squamous NSCLC With Oncogen HRAS MutAtionS [Phase 2]
Phase 2 trial of tipifarnib in advanced squamous non-small cell lung cancer with HRAS mutations has been terminated; results were posted in …
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer [Phase 2]
Phase 2 trial of AZD1775 in combination with carboplatin and paclitaxel for squamous cell carcinoma of the lung has completed and results ha…
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: Efficacy and Safety Study of Gefitinib in Squamous NSCLC Patients Who Failed First-Line Chemotherapy [Phase 2]
Phase 2 trial evaluating gefitinib for squamous cell carcinoma of the bronchus after failure of first-line chemotherapy; study completed.
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CLINICAL_TRIALS trial_result · 2023-02-14Clinical Trial Update: TQB2450 Injection Combined With Chemotherapy Followed by Sequential Combination With Anlotinib Hydrochloride Capsule for First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer. [Phase 3]
Phase 3 trial evaluating TQB2450 with chemotherapy followed by anlotinib for first-line treatment of advanced squamous non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer
A completed clinical trial update for Lung-MAP exploring biomarker-targeted second-line therapy in recurrent stage IV squamous cell lung can…
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CLINICAL_TRIALS trial_result · 2022-02-17Clinical Trial Update: Envafolimab Combined With Chemotherapy and Recombinant Human Endostatin in the First-line Treatment of Sq-NSCLC [Phase 2]
A Phase 2 trial exploring Envafolimab with chemotherapy and recombinant human endostatin as first-line treatment for squamous non-small cell…
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CLINICAL_TRIALS trial_result · 2022-01-21Clinical Trial Update: Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating durvalumab and tremelimumab in recurrent stage IV squamous cell lung carcinoma has completed with results …
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers [Phase 3]
Phase 3 Lung-MAP trial update evaluating nivolumab with or without ipilimumab as second-line therapy for recurrent Stage IV squamous cell ca…
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CLINICAL_TRIALS trial_result · 2021-11-24Clinical Trial Update: KN046 in Subjects With Advanced Squamous Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial update for KN046 in subjects with squamous non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-10-20Clinical Trial Update: A Study of Carboplatin-Paclitaxel/Nab-Paclitaxel Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With First Line Metastatic Squamous Non-small Cell Lung Cancer (MK-3475-407/KEYNOTE-407)-China Extension Study [Phase 3]
Phase 3 China extension study evaluating pembrolizumab added to carboplatin-paclitaxel or nab-paclitaxel as first-line therapy for metastati…
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer [Phase 2]
A Phase 2 trial assessing whether adding metformin hydrochloride to chemotherapy and radiation improves outcomes for Stage III non-small cel…