Squamous Cell Carcinoma of the Lung
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: RC148 Plus Platinum-Based Chemotherapy vs Tislelizumab Plus Platinum-Based Chemotherapy for First-Line Squamous Non-Small Cell Lung Cancer (sqNSCLC) [Phase 3]
A Phase 3 trial comparing RC148 plus platinum-based chemotherapy versus tislelizumab plus platinum-based chemotherapy for first-line squamou…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers [Phase 1, Phase 2]
A Phase Ib/II clinical trial evaluating HMBD-001, an anti-HER3 antibody, in combination with cetuximab with or without docetaxel for advance…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial update evaluating TT125-802 in adults with advanced solid tumors, focusing on safety, tolerability, pharmacokinetic…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023] [Phase 3]
A Phase 3 clinical trial evaluating pembrolizumab with or without maintenance Sac-TMT (MK-2870) in metastatic squamous non-small cell lung c…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [Phase 3]
Global Phase III trial evaluating Rilvegostomig or pembrolizumab plus chemotherapy as first-line treatment for metastatic squamous non-small…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC) [Phase 1]
This clinical trial update describes a Phase 1 study evaluating adverse events and changes in disease activity for intravenous ABBV-324 in a…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study of ZEN003694 in People With Squamous Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating ZEN003694 in patients with squamous cell carcinoma of the lung is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer [Phase 2, Phase 3]
A global Phase II/III trial evaluating HLX43 as a monotherapy or in combination with HLX07 versus docetaxel in advanced or metastatic squamo…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Prospective Data Collection Initiative on Thoracic Malignancies
A prospective data collection initiative on thoracic malignancies sponsored by the Dutch Society of Physicians for Pulmonology and Tuberculo…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating ALE.P02 as monotherapy in adults with CLDN1+ solid tumors, including squamous cell carcinomas of th…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery [NA]
This clinical trial update outlines a study of image-guided hypofractionated radiation therapy with a stereotactic body radiation therapy bo…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer [NA]
A clinical trial sponsored by Ohio State University Comprehensive Cancer Center is recruiting to test a protocol for improving survival in p…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Pilot Phase II Study of Maintenance Cabozantinib Plus Pembrolizumab for Patients With Metastatic Squamous Non-Small Cell Lung Cancer (sqNSCLC) [Phase 2]
A pilot Phase II clinical trial is evaluating maintenance cabozantinib plus pembrolizumab for metastatic squamous non-small cell lung cancer…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing safety, tolerability, and imaging with [68Ga]Ga-DPI-4452 and safety, tolerability, and efficacy…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma
A terminated clinical trial explored prognostic biomarkers for progression of invasive squamous cell carcinoma, with emphasis on squamous ce…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating safety and tolerability of BCA101 as monotherapy and in combination in EGFR-driven advanced solid tumors. The trial…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma [Phase 3]
Phase 3 clinical trial evaluating SI-B001 in combination with docetaxel for adenocarcinoma of the lung and squamous cell carcinoma of the lu…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Phase II Study of Platinum (Cisplatin/Carboplatin)and Polymeric Micelles Paclitaxel(Pm-Pac) With Ivonescimab in First Line Metastatic Squamous NSCLC. [Phase 2]
Phase II trial evaluating first-line treatment of metastatic squamous non-small cell lung cancer with cisplatin/carboplatin, polymeric micel…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer [Phase 2]
This entry covers the National Lung Matrix Trial, a multi-drug Phase II study in non-small cell lung cancer, with the trial currently active…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: To Evaluate the Efficacy and Safety of Inhaled Corticosteroids Combined With Bronchodilators and Programmed Death-ligand 1 (PD-L1) Inhibitor Plus Platinum-based Chemotherapy in Patients With Advanced Lung Squamous Cell Carcinoma Complicated With Chronic Obstructive Pulmonary Disease (COPD)
A clinical trial is evaluating whether adding inhaled corticosteroids and bronchodilators to a PD-L1 inhibitor plus platinum-based chemother…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma [Phase 2]
This clinical trial is evaluating ALK tyrosine kinase inhibitors in ALK-rearranged advanced squamous cell carcinoma (a form of non-small cel…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC Patients
An ongoing clinical study is investigating therapeutic resistance and clonal evolution in non-small cell lung cancer patients treated with i…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression [Phase 1]
Phase 1 trial evaluating GPC3-CAR-T cell therapy for glypican-3 expressing cancers. The study includes hepatocellular carcinoma and squamous…
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: Nab-Paclitaxel Versus Paclitaxel Plus Carboplatin in Advanced Squamous Cell Non Small Cell Lung Cancer [Phase 3]
A Phase 3 trial comparing nab-paclitaxel to paclitaxel plus carboplatin in advanced squamous cell non-small cell lung cancer; the study stat…