Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-09-03Clinical Trial Update: A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors [Phase 1]
Phase 1 trial update for RO7172508 in CEA-positive solid tumors; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Olanzapine Plus Fosaprepitant Standard Antiemetic Therapy in the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients Receiving High Emetic Risk Multi-day Chemotherapy: a Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study [Phase 3]
A Phase 3 randomized study evaluating olanzapine plus fosaprepitant with standard antiemetic therapy for preventing chemotherapy-induced nau…
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CLINICAL_TRIALS trial_result · 2020-09-01Clinical Trial Update: A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols [NA]
Trial update describing a rollover protocol to allow continued access to tivozanib for subjects enrolled in other tivozanib protocols; study…
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CLINICAL_TRIALS trial_result · 2020-08-26Clinical Trial Update: Mass Balance, Pharmacokinetics and Metabolism Study of IXAZOMIB [Phase 1]
Phase 1 study reporting mass balance, pharmacokinetics, and metabolism of ixazomib in patients with advanced solid tumors and lymphoma.
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CLINICAL_TRIALS trial_result · 2020-07-16Clinical Trial Update: Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 safety study of PLX3397 with Paclitaxel in patients with advanced solid tumors completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-07-10Clinical Trial Update: A Study of DS-2248 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 trial update for DS-2248 in advanced solid tumors; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-06-22Clinical Trial Update: Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors [Phase 1]
Phase 1 dose-escalation multi-arm trial evaluating MLN4924 (pevonedistat) with docetaxel, gemcitabine, or with carboplatin/paclitaxel in sol…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors. [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of p53 gene therapy in combination with immune checkpoint inhibitors for solid tumors …
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CLINICAL_TRIALS trial_result · 2020-05-21Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of INCB001158 with Epacadostat, with or without Pembrolizumab, in advanced solid tumors; trial terminated with results poste…
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CLINICAL_TRIALS trial_result · 2020-05-12Clinical Trial Update: A Phase 1/2, Open-Label, Dose-Escalation, Safety Study of INCAGN01949 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 open-label dose-escalation safety study of INCAGN01949 in subjects with advanced or metastatic solid tumors completed, with result…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Study of Pexidartinib in Asian Subjects With Advanced Solid Tumors [Phase 1]
Phase 1 trial update of pexidartinib in Asian subjects with advanced solid tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-17Clinical Trial Update: An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies [Phase 1, Phase 2]
Open-label phase 1/2 trial of the JAK inhibitor INCB052793 in patients with advanced solid tumors; study terminated with results posted in 2…
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CLINICAL_TRIALS research · 2020-03-31Clinical Trial Update: MEtoclopramide, DExamethasone or Axoli to Prevent or Delay Chemotherapy-induced Nausea and Vomiting in Moderately Emetogenic Non-AC-based Chemotherapy [Phase 3]
Phase 3 clinical trial evaluating metoclopramide, dexamethasone, or Axoli to prevent or delay chemotherapy-induced nausea and vomiting in mo…
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CLINICAL_TRIALS trial_result · 2020-03-31Clinical Trial Update: A Study of TAK-659 in Combination With Nivolumab in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of TAK-659 in combination with nivolumab in advanced solid tumors was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: Feasibility Clinical Study of Targeted and Genome-Wide Sequencing
Feasibility study evaluating targeted and genome-wide sequencing in solid tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Phase I Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of BVD-523 in Patients With Advanced Malignancies [Phase 1, Phase 2]
Phase I dose-escalation, safety, pharmacokinetic and pharmacodynamic study of BVD-523 in patients with advanced malignancies has completed.
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CLINICAL_TRIALS trial_result · 2020-03-05Clinical Trial Update: Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206) [Phase 1, Phase 2]
Phase 1/2 trial of azacitidine combined with pembrolizumab and epacadostat in advanced solid tumors was terminated. Results were posted in M…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Effect of Sapanisertib (MLN0128) on the QTc Interval in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 trial evaluating the effect of sapanisertib (MLN0128) on QTc interval in participants with advanced solid tumors; results posted.
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CLINICAL_TRIALS trial_result · 2020-03-02Clinical Trial Update: A Study of Anlotinib Combined With AK105 Injection in Subjects With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Advanced Solid Tumor [Phase 2]
Phase 2 trial evaluating the combination of Anlotinib with AK105 injections in MSI-H or dMMR advanced solid tumors.
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CLINICAL_TRIALS trial_result · 2020-02-20Clinical Trial Update: An Open-Label Pharmacokinetics and Safety Study of Talazoparib [Phase 1]
Phase 1 open-label pharmacokinetics and safety study of talazoparib in patients with advanced solid tumors has completed with results posted…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer [Phase 1, Phase 2]
Phase 1/2 trial update for an experimental in-situ cancer vaccine across multiple solid tumors, including breast, colorectal, prostate, mela…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: An Open-label, Dose Escalation, Pharmacodynamic, Pharmacokinetic, and Effect of Food Phase 1 Study of E7820 to Determine the Maximum Tolerated Dose Following Twice Daily Oral Administration in Subjects With Unresectable Solid Tumors [Phase 1]
Phase 1 open-label study of E7820 in unresectable solid tumors to determine maximum tolerated dose and assess pharmacodynamics/pharmacokinet…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Trastuzumab Biosimilar (Samfenet®) Plus Treatment of Physician's Choice (TPC) in Patients With HER2-positive Solid Tumor [Phase 2]
Phase 2 trial evaluating a trastuzumab biosimilar (Samfenet) plus physician's choice therapy for HER2-positive solid tumors. Status and resu…
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating MK-3475 (pembrolizumab) in combination with INCB024360 in various selected cancers; study completed with results …
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CLINICAL_TRIALS trial_result · 2019-10-28Clinical Trial Update: MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment [Phase 1]
Phase 1 trial of MM-398 (Nal-IRI) investigates tumor drug levels and feasibility of using ferumoxytol-enhanced MRI to measure tumor-associat…