Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-05-20Clinical Trial Update: Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors [Phase 1]
Phase 1b trial evaluating lenvatinib plus pembrolizumab in selected solid tumors has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Phase 1/2 Study to Evaluate MEDI4736 [Phase 1, Phase 2]
Phase 1/2 study update for MEDI4736 (durvalumab) in advanced solid tumors; completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors [Phase 1]
Phase 1 multicenter study of PM060184 in combination with gemcitabine in selected patients with advanced solid tumors completed; results pos…
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: Arsenic Trioxide in Refractory Solid Tumors With Rescuable p53 Mutation [Phase 2]
A Phase 2 clinical trial evaluating arsenic trioxide in patients with refractory solid tumors possessing rescuable p53 mutations.
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CLINICAL_TRIALS trial_result · 2021-04-23Clinical Trial Update: Safety, Tolerability, and Immunoregulatory Activity of Mogamulizumab (KW-0761) in Subjects With Advanced and/or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety, tolerability, and immunoregulatory activity of mogamulizumab (KW-0761) in patients with advanced or metas…
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CLINICAL_TRIALS trial_result · 2021-04-22Clinical Trial Update: K-BASKET, TAS-117, PI3K/AKT Gene Aberration [Phase 2]
Phase 2 clinical trial update (K-BASKET) evaluating TAS-117 targeting PI3K/AKT gene aberrations in solid tumors completed.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Extension Study of EC145 (Vintafolide) for Subjects Enrolled in a Previous Study With EC145 (MK-8109-010) [Phase 2]
Phase 2 extension study update for EC145 (Vintafolide) in subjects from a previous MK-8109-010 study; study status is completed.
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CLINICAL_TRIALS trial_result · 2021-03-01Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors [Phase 2]
Phase 2 study evaluating cobimetinib plus atezolizumab in solid tumors has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800) [Phase 1]
Phase 1 open-label pharmacokinetics and safety study of talazoparib (MDV3800) in advanced solid tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers [Phase 2]
A Phase II trial evaluating nivolumab in patients with DNA damage repair gene alterations who progressed after standard treatment for metast…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: First in Human Study of IBI308 in Chinese Subjects With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of IBI308 in Chinese subjects with advanced solid tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) [Phase 2]
Open-label extension study of Conatumumab and Ganitumab (AMG 479) in a Phase 2 trial for advanced solid tumors; completed with results poste…
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CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: An Extension Protocol for Subjects Who Were Previously Enrolled in Other Tivantinib (ARQ 197) Protocols [Phase 1, Phase 2]
An extension protocol update for subjects previously enrolled in other tivantinib (ARQ 197) protocols across Phase 1 and Phase 2 trials; stu…
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations [Phase 1, Phase 2]
Pilot trial of BMN 673 (olaparib) in advanced solid tumors with deleterious BRCA mutations completed phases 1 and 2; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Phase I Dose Escalation Trial of Efavirenz in Solid Tumours or Non-Hodgkin Lymphoma in Therapeutic Failure. [Phase 1]
Phase I dose-escalation study of efavirenz in solid tumors and non-Hodgkin lymphoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-14Clinical Trial Update: Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors [Phase 1, Phase 2]
Phase 1/2 dose-escalation trial evaluating birinapant with pembrolizumab in solid tumors; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: FGFR4 Inhibitor EVER4010001 in Combination With PD-1 Inhibitor Pembrolizumab in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
An early-phase trial evaluating EVER4010001, an FGFR4 inhibitor, in combination with pembrolizumab for advanced solid tumors is in Phase 1/P…
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CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203) [Phase 1, Phase 2]
Phase 1/2 study of epacadostat plus durvalumab in selected advanced solid tumors completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alobresib (Formerly GS-5829) in Adults With Advanced Solid Tumors and Lymphomas and in Combination With Exemestane or Fulvestrant in Adults With Estrogen Receptor Positive Breast Cancer [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of alobresib (GS-5829) in adults with advanced solid t…
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CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 trial assessing relative bioavailability, food effect, and gastric pH modification on TAK-931 pharmacokinetics in participants with …
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: FGF401 in HCC and Solid Tumors Characterized by Positive FGFR4 and KLB Expression [Phase 1, Phase 2]
Phase 1/2 study of FGF401 in hepatocellular carcinoma and other solid tumors characterized by FGFR4 and KLB expression has completed. Result…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer [Phase 1, Phase 2]
Phase I/II trial update for BGT226 in adults with advanced solid malignancies including breast cancer; study completed.
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CLINICAL_TRIALS trial_result · 2020-11-19Clinical Trial Update: Phase I/Ib Study of Nivolumab & Veliparib in Patients With Advanced Solid Tumors & Lymphoma [Phase 1]
This Phase I/Ib trial assesses safety and early efficacy signals for nivolumab plus veliparib in patients with advanced solid tumors and agg…
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CLINICAL_TRIALS trial_result · 2020-10-05Clinical Trial Update: An Investigational Immuno-therapy Study to Determine the Safety of Urelumab Given in Combination With Nivolumab in Solid Tumors and B-cell Non-Hodgkin's Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating urelumab with nivolumab in advanced solid tumors and advanced B-cell non-Hodgkin's lymphoma was terminated.
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor JPN) [Phase 1]
Phase 1 trial update of avelumab in metastatic or locally advanced solid tumors completed with results posted.