Solid Tumors
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors [Phase 1]
Phase 1 study assessing pharmacokinetics and safety of MRX-2843 in adults with relapsed/refractory advanced and/or metastatic solid tumors; …
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Dose-escalation Study of APG-1387 and Toripalimab in Solid Tumors [Phase 1, Phase 2]
A dose-escalation study of APG-1387 in combination with toripalimab in advanced solid tumors has been terminated after Phase 1/Phase 2 evalu…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: A Phase 1b/2 Study of ADG116, ADG116 Combined With Anti-PD-1 Antibody or Anti-CD137 Antibody in Solid Tumors Patients [Phase 1]
This entry reports a completed Phase 1b/2 trial evaluating ADG116 alone and in combination with anti-PD-1 or anti-CD137 antibodies in patien…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors [Phase 1]
Phase 1 trial assessing safety and pharmacokinetics of the BGB-283 (lifirafenib) and PD-0325901 (mirdametinib) combination in adults with ad…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8006 for Injection [Phase 1]
Phase 1 study evaluating the safety, tolerability and pharmacokinetics of BAT8006 in patients with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial of WTX-330 in patients with advanced or metastatic solid tumors or non-Hodgkin lymphoma has completed enrollment and posted re…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 study of Tuvusertib in combination with PLX038 in patients with advanced solid tumors was terminated.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Randomized Phase II Study to Evaluate Efficacy of Web-based Patient-reported Outcome (PRO) Application in Solid Cancer Patients [NA]
A randomized Phase II trial evaluating a web-based patient-reported outcome (PRO) application in patients with solid cancers has completed.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Preclinical Safety Evaluation and First-in-Human Translational Study of [177Lu]Lu-TEFAPI-06 [EARLY_Phase 1]
This update reports preclinical safety evaluation and the first-in-human translational study of [177Lu]Lu-TEFAPI-06 for metastatic solid tum…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903 [Phase 1]
Phase 1 study of RP903 conducted by Risen (Suzhou) Pharma Tech Co., Ltd. has completed, evaluating safety, tolerability, pharmacokinetics, e…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: A Study to Assess the Safety and Tolerability of RC88 for Patients With Advanced Solid Tumours [Phase 1, Phase 2]
A completed Phase 1/Phase 2 study evaluating the safety and tolerability of RC88 in patients with solid tumors.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Clinical Trial of Rapamycin and Irinotecan in Pediatric Patients With Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating the safety of combining rapamycin with irinotecan in pediatric patients with refractory solid tumors; the study has…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: KZR-261 in Subjects With Advanced Solid Malignancies [Phase 1]
A Phase 1 study of KZR-261 in subjects with advanced/metastatic solid tumors was terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated safety, tolerability, and pharmacokinetics/pharmacodynamics of ASC61 in adults with advanced solid tumors. The …
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS [Phase 1]
Phase 1 study of JNJ-64619178, a PRMT5 inhibitor, in participants with advanced solid tumors, Non-Hodgkin Lymphoma, and lower-risk myelodysp…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome [Phase 4]
Phase 4 clinical trial update examining pegloticase for lowering uric acid in patients with tumor lysis syndrome; the study is active but no…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 trial evaluating BMS-986315 alone and in combination with nivolumab or cetuximab in adults…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: RE002 T Cell Injection for the Treatment of KRAS G12D Mutated Solid Tumors [Phase 1]
Phase 1 trial RE002 T cell injection is assessing safety and preliminary efficacy in KRAS G12D-mutated solid tumors; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Varian ProBeam360° Proton Therapy System China Clinical Trial (Wuhan) [NA]
A China-based clinical trial evaluating Varian's ProBeam360° proton therapy system for solid tumors has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT1308 in Advanced Solid Tumors [Phase 1]
Phase 1 trial evaluating BAT1308 in advanced solid tumors for safety, tolerability, pharmacokinetics, and preliminary efficacy; the study is…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Study of SKB107 in Advanced Solid Tumors With Bone Metastases [Phase 1]
Phase 1 clinical trial of SKB107 in advanced solid tumors with bone metastases is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers [Phase 1]
Phase 1 trial evaluating the safety and potential activity of recombinant interleukin-15 in combination with nivolumab and ipilimumab in pat…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Safety and Tolerability Evaluation of CEL001 Injection in Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the safety and tolerability of CEL001 Injection in patients with advanced solid tumors; the trial is currently recr…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition [Phase 2, Phase 3]
The update notes ongoing recruitment for the DETERMINE trial Arm 02 investigating atezolizumab in adults and pediatric/young adult patients …
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: LIONS (PLK4 Inhibitor in Advanced Solid Tumors) [Phase 1]
An early-phase (Phase 1) trial of an investigational PLK4 inhibitor in patients with advanced solid tumors was terminated; results were post…