Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3) [Phase 3]
Phase 3 clinical trial investigating intratumoral INT230-6 versus US standard of care in adults with soft tissue sarcoma; the study is curre…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma [Phase 1]
A Phase 1 trial evaluating DPPG2-TSL-DOX in combination with hyperthermia for soft tissue sarcoma has completed.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating MASCT-I in combination with doxorubicin and ifosfamide as first-line therapy for advanced soft tissue sarcoma is …
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration [Phase 2]
A Phase 2 clinical trial evaluating abemaciclib for bone and soft tissue sarcomas with CDK pathway alterations is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma [Phase 2]
This clinical trial update describes a Phase 2 study evaluating Cadonilimab in combination with Adriamycin (doxorubicin) in patients with ad…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities [Phase 1, Phase 2]
Phase 1/2 trial evaluating cabozantinib with radiation therapy for soft tissue sarcoma of the trunk and extremities was terminated, with res…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial is evaluating pazopanib with or without pembrolizumab for metastatic soft tissue sarcoma. The study is currently re…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study of sequential infusion of CD146-targeted and HER2-targeted CAR T cells in patients with…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Biopsy Needle Size in Soft Tissue Sarcoma [NA]
A completed clinical trial from Ankara City Hospital Bilkent assessing biopsy needle size in soft tissue sarcoma.
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies [Phase 1, Phase 2]
SPEDOX-6, a single protein encapsulated doxorubicin, is being studied in Phase 1/2 trials for several advanced cancers and is currently recr…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling [Phase 1]
Phase 1 clinical trial evaluating ex vivo drug sensitivity testing and multi-omics profiling in pediatric cancers. Recruitment is ongoing ac…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas
Completed clinical trial evaluating Fluorodopa F-18 PET/MRI to assess treatment response in high-grade soft tissue sarcoma, highlighting ima…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas [Phase 1]
This document reports a Phase 1 clinical trial evaluating the safety and efficacy of DIT309 in advanced bone and soft tissue sarcomas, with …
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Proton Radiation for the Treatment of Pediatric Bone and Non-Rhabdomyosarcoma Soft Tissue Sarcomas [NA]
A completed clinical trial evaluating proton radiation for pediatric bone sarcoma and non-rhabdomyosarcoma soft tissue sarcoma, with results…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc) [Phase 2]
Phase 2 trial of Selinexor in combination with gemcitabine for selected advanced soft-tissue sarcoma is currently recruiting in the SeliSarc…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Pre-operative RadiothErapy for Soft Tissue SarcOmas [NA]
This clinical trial update describes a pre-operative radiotherapy approach for soft tissue sarcoma, with the study currently active but not …
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CLINICAL_TRIALS other · 2025-06-25Clinical Trial Update: FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER) [Phase 1]
A Phase 1 dose-escalation trial of Lu-177-labeled PNT6555 (FRONTIER) for selected solid tumors assessing safety, tolerability and dosimetry;…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide [Phase 1]
Phase I dose-escalation study of azacitidine in combination with temozolomide in soft tissue sarcoma and mesothelioma has completed with res…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa. [Phase 2]
A Phase 2 clinical trial evaluating pre-operative hypofractionated radiation therapy in elderly or frail patients with limb or trunk soft ti…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Spatially Fractionated Radiotherapy Versus Conventional Radiotherapy in the Treatment of Soft Tissue Sarcoma [NA]
A clinical trial is comparing spatially fractionated radiotherapy with conventional radiotherapy for soft tissue sarcoma and is currently re…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients [Phase 1]
Phase 1 study evaluating different dosing schedules of Selinexor in soft tissue sarcoma and related tumors has completed.
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Prehabilitation in Childhood Soft Tissue or Bone Sarcomas [NA]
A pediatric prehabilitation study for childhood soft tissue sarcoma and bone tumors is currently enrolling by invitation at the Technical Un…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Tranexamic Acid in Radical Resection and Endoprosthetic Reconstruction [Phase 4]
Phase 4 trial evaluating tranexamic acid during radical resection and endoprosthetic reconstruction for musculoskeletal cancers was terminat…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma [NA]
A clinical trial update describes a study evaluating whether early psychiatric referral improves mental health and quality of life in people…