Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) [Phase 1, Phase 2]
PMV Pharmaceuticals is evaluating PC14586 in a Phase 1/2 trial for advanced solid tumors harboring the TP53 Y220C mutation. The study is cur…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of Alisertib and Paclitaxel in Patients With Small Cell Lung Cancer (SCLC) [Phase 2]
This update describes a Phase 2 clinical trial evaluating alisertib in combination with paclitaxel for small cell lung cancer, which is curr…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: SCLC Tarlatamab Blood Collection
Duke University is conducting a small-cell lung cancer trial of tarlatamab, which is currently not yet recruiting and involves blood collect…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC [Phase 1, Phase 2]
An early-phase, biomarker-directed trial is evaluating temozolomide in combination with stenoparib for relapsed small cell lung cancer and i…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON) [Phase 3]
Phase 3 trial update (LAGOON) evaluating lurbinectedin as a single agent or with irinotecan compared with topotecan or irinotecan in relapse…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer [Phase 1, Phase 2]
A clinical study to assess the safety and tolerability of BMS-986525 alone and with nivolumab in relapsed/refractory small cell lung cancer,…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SNB-101 for extensive-stage small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Study of AK112 as Consolidation Treatment for Patients With Limited Stage Small-cell Lung Cancer Who Have Not Progressed Following Concurrent Chemoradiation Therapy [Phase 3]
This document provides an update on a Phase 3 clinical trial evaluating AK112 as consolidation therapy for patients with limited-stage small…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: PD-L1 Targeting Peptide Probe for PET Imaging of Solid Tumor
A clinical trial update describes a PD-L1–targeting peptide probe for PET imaging of solid tumors, with not-yet-recruiting status and condit…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Talazoparib and Thoracic RT for ES-SCLC [Phase 1]
Phase 1 clinical trial evaluating talazoparib in combination with thoracic radiotherapy for extensive-stage small cell lung cancer is curren…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis [Phase 2]
A Phase 2 study is evaluating stereotactic radiosurgery for brain metastases from small cell lung cancer. The trial is currently active but …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of FZ-AD005 in Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 study evaluating FZ-AD005 in adults with advanced solid tumors, including small cell lung cancer and large cell neuroendoc…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer [Phase 1]
A Phase 1 trial evaluating ZG006 in combination with PD-1/PD-L1 inhibitors as first-line therapy for extensive-stage small cell lung cancer.…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES) [Phase 2]
This entry describes a Phase 2 trial investigating durvalumab with ablative radiation for small-cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Concurrent or Sequential Immunotherapy and Radiation Therapy in Patients With Metastatic Lung Cancer [Phase 1]
This clinical trial update discusses a Phase 1 study of concurrent or sequential immunotherapy and radiation therapy in patients with metast…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC [Phase 2]
A Phase 2, open-label, randomized, multicenter study evaluating different dosing regimens of tarlatamab in patients with small cell lung can…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: First in Human Study of TUB-030 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
First-in-human study of TUB-030 is underway in patients with advanced solid tumors, including head and neck squamous cell carcinoma, small c…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Study of Oral MRT-2359 in Selected Cancer Patients [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 trial evaluating MRT-2359 in multiple cancer indications; trial is active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Engagement of Veterans With Lung Cancer [NA]
A clinical trial update indicates the study sponsored by Palo Alto Veterans Institute for Research is currently recruiting veterans with var…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer [Phase 3]
A Phase 3 trial comparing Ifinatamab Deruxtecan to physician's choice in relapsed small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients. [Phase 3]
Phase 3 clinical trial evaluating adding anlotinib to whole-brain radiotherapy in small cell lung cancer patients with brain metastases; cur…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Efficacy and Safety of Standard of Care Plus Durvalumab in Patients With Limited Disease Small Cell Lung Cancer (DOLPHIN) [Phase 2]
Phase 2 trial evaluating the addition of durvalumab to standard of care in limited-stage small cell lung cancer, with reported efficacy and …
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FDA approval · 2026-02-27FDA Approved: ZEPZELCA — Supplemental Application (Jazz Pharmaceuticals, Inc.)
FDA approved a supplemental application for ZEPZELCA (lurbinectedin) filed by Jazz Pharmaceuticals, expanding the regulatory status of the p…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC [Phase 2]
A Phase 2 clinical trial evaluating golidocitinib in combination with PD-1 inhibitors as maintenance therapy for previously untreated extens…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Real-World Study Evaluating the Efficacy and Safety of Adebrelimab in Patients With Advanced SCLC
A real-world study evaluating the efficacy and safety of Adebrelimab in patients with advanced Small Cell Lung Cancer. Recruitment is ongoin…