Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-12-21Clinical Trial Update: A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU) [Phase 3]
Phase 3 trial of rovalpituzumab tesirine as maintenance therapy after first-line platinum-based chemotherapy in extensive-stage small cell l…
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CLINICAL_TRIALS trial_result · 2020-12-09Clinical Trial Update: Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer [Phase 2, Phase 3]
A phase 2/3 trial evaluating dinutuximab plus irinotecan versus irinotecan alone in relapsed or refractory small cell lung cancer has comple…
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CLINICAL_TRIALS trial_result · 2020-12-09Clinical Trial Update: A Study of Fluzoparib Combined With Apatinib as Second-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer（FA-ES-SCLC） [Phase 1, Phase 2]
Clinical trial update investigating fluzoparib in combination with apatinib as second-line therapy for extensive-stage small cell lung cance…
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CLINICAL_TRIALS trial_result · 2020-12-01Clinical Trial Update: A Prospective, Single-center, One-arm Clinical Study of Apatinib Combined With Chemotherapy for Pretreated Patients With Advanced Small Cell Lung Cancer [Phase 2]
A Phase 2 single-arm study evaluating apatinib plus chemotherapy in pretreated advanced small cell lung cancer has been completed.
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CLINICAL_TRIALS trial_result · 2020-11-09Clinical Trial Update: Tislelizumab in Combination With Anlotinib With ES-SCLC as Maintenance Therapy After First Line Chemotherapy [Phase 2]
Phase 2 trial investigating tislelizumab plus anlotinib as maintenance therapy after first-line chemotherapy in extensive-stage small cell l…
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: Study of Enzastaurin Versus Placebo in the Treatment of Patients With Brain Metastases of Lung Cancer, After Whole Brain Radiation Therapy [Phase 2]
Phase 2 trial evaluating enzastaurin versus placebo for brain metastases from lung cancer after whole-brain radiation therapy has completed …
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CLINICAL_TRIALS withdrawal · 2020-10-30Clinical Trial Update: Evaluate the Safety, Tolerability, Biodistribution and Anti Tumour Activity of 177LU-OPS201 With Companion Imaging 68Ga-OPS202 PET/CT in Previously Treated Subjects With Locally Advanced or Metastatic Cancers Expressing Somatostatin Receptor 2 (SSTR2) [Phase 1, Phase 2]
Phase 1/2 trial evaluating 177Lu-OPS201 with 68Ga-OPS202 imaging in somatostatin receptor 2–expressing cancers; study terminated with posted…
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CLINICAL_TRIALS trial_result · 2020-10-23Clinical Trial Update: [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR) [Phase 2]
Phase 2 imaging trial evaluating [68Ga]-NeoBOMB1 for GRPR-expressing tumors has terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer [NA]
Clinical trial completion for hippocampal prophylactic cranial irradiation in small cell lung cancer with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: A Prospective Study Comparing Two Radiotherapy Dose/Fraction and Omitting CTVs of the Primary Tumor in Limited SCLC [Phase 2]
Phase 2 trial updating radiotherapy dose/fractionation and omission of CTVs in limited-stage small cell lung cancer (SCLC).
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: PCI for Patients With ES-SCLC After RCT:a Prospective Randomized Study [Phase 3]
A Phase 3 randomized study evaluating PCI for patients with extensive-stage small-cell lung cancer following a prior randomized trial.
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FDA approval · 2020-08-20FDA Approved: TOPOTECAN HYDROCHLORIDE — Supplemental Application (Accord Healthcare, Inc.)
FDA approved Accord Healthcare's supplemental application for Topotecan Hydrochloride, a generic chemotherapy drug, supporting its labeling …
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: A Study of Gimatecan (ST1481) in Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update for gimatecan (ST1481) in small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2020-07-10Clinical Trial Update: Study of Apatinib Plus Etoposide Capsule as the Therapy of Advanced Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating apatinib plus etoposide capsules for advanced small cell lung cancer (SCLC).
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CLINICAL_TRIALS trial_result · 2020-07-09Clinical Trial Update: Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Etoposide and Carboplatin in Extensive Stage Small Cell Lung Cancer (SCLC) [Phase 1, Phase 2]
Clinical trial update for Trilaciclib in combination with etoposide and carboplatin in extensive-stage small cell lung cancer (Phase 1/2) co…
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CLINICAL_TRIALS trial_result · 2020-07-09Clinical Trial Update: CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC) [Phase 2]
Phase 2 clinical trial update for CM082 and JS001 in patients with advanced small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer [Phase 1, Phase 2]
Clinical trial investigating rovalpituzumab tesirine in combination with nivolumab, with or without ipilimumab, in adults with extensive-sta…
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FDA approval · 2020-06-15FDA Approved: ZEPZELCA — Original Application (Jazz Pharmaceuticals, Inc.)
The FDA approved Zepzelca (lurbinectedin) from Jazz Pharmaceuticals in an original-application approval for adult patients with metastatic s…
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CLINICAL_TRIALS trial_result · 2020-06-11Clinical Trial Update: Study of Sintlimab Maintenance Therapy in Patients With Extensive Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update for sintilimab maintenance therapy in patients with extensive small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2020-05-14Clinical Trial Update: Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating veliparib with carboplatin and etoposide in treatment-naive extensive-stage small cell lung cancer has c…
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CLINICAL_TRIALS trial_result · 2020-04-29Clinical Trial Update: Diflomotecan (BN80915) Administered Once Every 3 Weeks in Treating Patients With Sensitive Small Cell Lung Cancer (SCLC) [Phase 2]
Phase 2 trial update for diflomotecan (BN80915) given every 3 weeks in sensitive small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: First-line Chemotherapy Followed by Toripalimab Combined With Anlotinib for Maintenance in ES-SCLC [Phase 2]
Phase 2 trial update evaluating first-line chemotherapy followed by toripalimab plus anlotinib for maintenance in extensive-stage small cell…
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial investigating topotecan hydrochloride or CRLX101 (cyclodextrin-based polymer-camptothecin) for recurrent small cell l…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Marimastat Following Chemotherapy in Treating Patients With Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial evaluated marimastat after chemotherapy in patients with small cell lung cancer and has completed.
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid Tumors [Phase 1]
Phase I study of lurbinectedin in combination with paclitaxel, with or without bevacizumab, in selected advanced solid tumors (completed; re…