Small Cell Lung Cancer
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Searching for Predictive Biomarkers of Efficacy in Small Cell Lung Cancer Patients Treated With Chemotherapy-immunotherapy Combination Using Imaging Mass Cytometry (HYPE)
An ongoing study to identify predictive biomarkers of efficacy in small cell lung cancer patients treated with a chemotherapy-immunotherapy …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Real-life Second-line Epirubicin-Paclitaxel Regimen as Treatment of Relapsed Small-Cell Lung Cancer : EpiTax Study.
The EpiTax study (NCT06550518) reports completion of a real-world evaluation of a second-line epirubicin-paclitaxel regimen for relapsed sma…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy [Phase 2]
Phase 2 trial evaluating the combination of camrelizumab (SHR-1210) and apatinib in extensive-disease small-cell lung cancer after failure o…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancer [Phase 2]
This update notes that the Phase 2, open-label study of amuvatinib with platinum-etoposide chemotherapy in small cell lung cancer has comple…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study [Phase 2]
Open-phase 2 multicenter trial evaluating Milaberon in advanced solid tumors across multiple indications, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors [Phase 2]
A Phase 2 trial evaluating Cediranib in combination with Olaparib in advanced solid tumors has posted results as of 2024-07-30. Indications …
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: A Study of HS-20093 vs Active Surveillance in Limited-Stage Small Cell Lung Cancer [Phase 3]
This document describes a Phase 3 clinical trial comparing HS-20093 to active surveillance in patients with limited-stage small cell lung ca…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating low-dose radiotherapy with cisplatin/carboplatin, etoposide, and atezolizumab in extensive-stage small cell lung …
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: IMFINZI Study in Patients With Extensive Stage Small Cell Lung Cancer
A study evaluating durvalumab (Imfinzi) in patients with extensive-stage small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Chemoimmunotherapy Plus Residual Lesion Irradiation for the Treatment of Extensive Stage Small-cell Lung Cancer
An ongoing clinical trial evaluating chemoimmunotherapy plus irradiation of residual lesions for extensive-stage small-cell lung cancer, cur…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Serplulimab Combined With CCRT for LS-SCLC. [Phase 2]
Phase 2 trial evaluating serplulimab in combination with concurrent chemoradiotherapy for limited-stage small cell lung cancer is currently …
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating atezolizumab with carboplatin and etoposide for untreated extensive-stage small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC. [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Chiauranib in patients with small cell lung cancer and advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: Mass Balance Study of [14C]Chiauranib [NA]
The mass balance pharmacokinetic study of [14C]Chiauranib has completed for Small cell lung cancer, as reported by Chipscreen Biosciences.
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: An Exploratory Study of Lurbinectedin With Radiotherapy in Locally-advanced SCLC After First-line Therapy [Phase 2]
An exploratory Phase 2 study of lurbinectedin combined with radiotherapy for locally-advanced small cell lung cancer after first-line therap…
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Small Cell Lung Cancer Patients [Phase 3]
Phase 3 trial evaluating trilaciclib for efficacy, safety, and pharmacokinetics in extensive-stage small cell lung cancer has completed and …
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Study of Irinotecan Liposome Injection as Second-line Regimen in Patients With Small Cell Lung Cancer (SCLC) [Phase 2]
Phase 2 study evaluating irinotecan liposome injection as a second-line regimen for small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Efficacy and Safety Study of a New Therapeutic Strategy in the Treatment of Extended-Disease Small-Cell Lung Cancer [Phase 2]
This update reports the completion of a Phase 2 efficacy and safety study evaluating a new therapeutic strategy for extended-disease small c…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trial [Phase 2]
A Phase 2 randomized neoadjuvant trial of adebrelimab for resectable small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: The Predictive Value of Proteome Profiling for Brain Metastasis in Limited-Stage Small-Cell Lung Cancer
Updates on a clinical trial assessing whether proteome profiling can predict brain metastasis in patients with limited-stage small-cell lung…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: A Clinical Study of TQB2450 Combined With Anlotinib in Limited-Stage Small Cell Lung Cancer Patients [Phase 3]
A Phase 3 clinical trial evaluating TQB2450 in combination with Anlotinib for limited-stage small cell lung cancer; recruitment status is no…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases [Phase 2]
Phase 2 clinical trial update evaluating the combination of radiosurgery and nivolumab for brain metastases in various cancers, with complet…
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CLINICAL_TRIALS research · 2024-06-28Clinical Trial Update: Liposomal Irinotecan Combination Regimen for First-line Treatment of Small Cell Lung Cancer [NA]
A clinical trial is evaluating a liposomal irinotecan combination as first-line therapy for small cell lung cancer, with the study currently…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Cell Lung Cancer [Phase 2, Phase 3]
A phase 2/3 trial evaluated whole-brain radiation therapy with or without hippocampal avoidance in patients with limited-stage or extensive-…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Phase 1b/2 Study of LDRT in Combination With AK104 Plus Chemotherapy as First-line Treatment for ES-SCLC [Phase 1, Phase 2]
A Phase 1b/2 clinical trial is evaluating low-dose radiotherapy in combination with AK104 and chemotherapy as first-line treatment for exten…