Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC [Phase 1]
Phase 1 study of AMG 119 in relapsed or refractory small cell lung cancer is currently suspended.
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants. [Phase 1]
A Phase 1 pharmacokinetic study evaluating JDQ443 in participants with hepatic impairment compared with matched healthy controls has complet…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers [Phase 2]
Phase II trial of XmAb20717 for advanced rare cancers has been suspended, with eligibility including microsatellite instability-high cancers…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial of NKT3447 in adults with advanced or metastatic solid tumors has been terminated. The study encompassed indications including…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Durvalumab Plus Etoposide-free Chemotherapy in First-line Treatment of Extensive-disease Small-sell Lung Cancer (SCLC) [Phase 2]
Phase 2 trial evaluating durvalumab with etoposide-free chemotherapy as first-line treatment for extensive-stage small cell lung cancer; cur…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) [Phase 2]
Pembrolizumab is being studied in a Phase 2 trial (MK-3475-158/KEYNOTE-158) for advanced solid tumors; the study is currently active but not…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update reports results from evaluating the combination of sirolimus and auranofin in patients with advanced…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors [Phase 1]
This Phase 1 trial assesses safety, tolerability, and preliminary efficacy of lomvastomig, a PD-1/TIM-3 bispecific antibody, in adults with …
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Irinotecan Liposome Combined With Anlotinib as Second-line Regimen for SCLC [NA]
An ongoing study sponsored by Fudan University is evaluating a combination of liposomal irinotecan and anlotinib as a second-line treatment …
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapy [Phase 3]
Phase 3 study evaluating durvalumab with tremelimumab versus durvalumab alone and placebo in limited-stage small cell lung cancer patients w…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET [Phase 2]
A Phase 2 trial of iadademstat in combination with paclitaxel for relapsed/refractory small-cell lung cancer and extrapulmonary high-grade n…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Pharmacogenomics ANDA SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms [Phase 2, Phase 3]
Clinical trial update for a pharmacogenomics study of etoposide in small cell lung cancer, spanning Phase 2 and Phase 3, with status active …
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99) [Phase 2]
Phase 2 results evaluate pembrolizumab in combination with chemotherapy and investigational agents as first-line therapy for extensive-stage…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy [Phase 2]
This Phase 2 trial evaluates the combination of ipilimumab and nivolumab in patients with recurrent extensive-stage small cell lung cancer f…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors [Phase 2]
Telix's phase 2 trial of the CAIX-targeting PET tracer 89Zr-girentuximab in CAIX-positive solid tumors was terminated.
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer [Phase 1, Phase 2]
NCI-sponsored trial EP0057 (camptothecin nanoparticle) combined with olaparib in relapsed/refractory small cell lung cancer completed Phase …
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013) [Phase 3]
Phase 3 trial evaluating concurrent chemoradiation with pembrolizumab, followed by pembrolizumab and olaparib, in newly diagnosed treatment-…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: A Study of Fluzoparib (SHR-3162) and Temozolomide With or Without SHR-1316 in Treating Patients With Replapsed Small Cell Lung Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating Fluzoparib (SHR-3162) with temozolomide, with or without SHR-1316, in relapsed small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: REAL-WORLD DURVALUMAB IN EXTENSIVE-STAGE SMALL CELL LUNG CANCER
Clinical trial update showing real-world use of durvalumab in extensive-stage small cell lung cancer; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery [Phase 3]
Phase 3 trial comparing hippocampus-sparing whole-brain radiotherapy to stereotactic radiosurgery for patients with brain metastases from va…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial of pembrolizumab after radiation therapy and chemotherapy in limited-stage small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer. [Phase 1, Phase 2]
Clinical trial evaluating the combination of lurbinectedin and pembrolizumab in small cell lung cancer. The study's Phase 1 and Phase 2 port…
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008) [Phase 3]
A Phase 3 trial evaluating pembrolizumab plus vibostolimab (MK-7684A) or atezolizumab in combination with chemotherapy as first-line treatme…