Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer [Phase 1]
Legend Biotech is conducting a Phase 1 trial of DLL3-directed CAR T-cells for extensive-stage small cell lung cancer, with inclusion of larg…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Efficacy and Safety of Standard of Care Plus Durvalumab in Patients With Limited Disease Small Cell Lung Cancer (DOLPHIN) [Phase 2]
Phase 2 trial evaluating the addition of durvalumab to standard of care in limited-stage small cell lung cancer, with reported efficacy and …
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of the triple combination niraparib, temozolomide, and atezolizumab in patients with …
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Durvalumab After Concurrent Chemoradiotherapy (cCRT) for Limited-stage Small-cell Lung Cancer (LS-SCLC)
An update on a trial evaluating durvalumab after concurrent chemoradiotherapy in limited-stage small-cell lung cancer, with the study status…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Adebrelimab Combined With Oral Etoposide for Elderly Patients and Patients With Poor Performance Status in Small Cell Lung Cancer: An Exploratory Clinical Study [Phase 2]
The document describes a Phase 2 exploratory study evaluating Adebrelimab plus oral etoposide in elderly or poor performance status patients…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating NT-I7 (efineptakin alfa) in combination with pembrolizumab in adults with advanced solid tumors has completed and…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors [Phase 2]
A Phase 2 study evaluating vobramitamab duocarmazine in metastatic castration-resistant prostate cancer and other solid tumors was terminate…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Safety and Efficacy Analysis of Oral Etoposide Combined With Anlotinib and Envafolimab in First-line Treatment of Elderly Patients With Small Cell Lung Cancer/ Open-label, Single-arm, Exploratory Phase II Clinical Study [Phase 2]
This open-label, single-arm Phase II trial evaluates the safety and potential efficacy of combining oral etoposide with Anlotinib and Envafo…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 ) [Phase 1, Phase 2]
A phase 1/2 clinical trial of radiopharmaceutical 225Ac-SS0110 in extensive-stage small cell lung cancer and Merkel cell carcinoma has been …
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Adebrelimab Maintenance Therapy for LS-SCLC Post Induction Chemo-Adebrelimab Plus CRT or CRT Alone [Phase 2]
A Phase 2 clinical trial investigates maintenance therapy with Adebrelimab for localized small cell lung cancer after induction chemo with A…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Chemo-immunotherapy Plus Thoracic Radiotherapy in Extensive Stage Small-cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating chemo-immunotherapy plus thoracic radiotherapy for extensive-stage small-cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors [Phase 1]
Phase 1 dose-finding study evaluating safety, tolerability, and pharmacokinetics of SNB-101 (SN-38) in patients with colorectal, breast, pan…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: SLV-154 Treatment of Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update for SLV-154 evaluating treatment of metastatic solid tumors. The study is currently recruiting across multiple…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Anlotinib Plus Penpulimab as Second-line Treatment for Patients With Small Cell Lung Cancer After Failure of Platinum-based Chemotherapy [Phase 2]
Phase 2 clinical trial evaluating the combination of anlotinib and penpulimab as second-line therapy for small cell lung cancer after platin…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer [Phase 3]
This clinical trial update reports results from a Phase 3 study comparing tarlatamab to standard-of-care chemotherapy in relapsed small cell…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: CXCR4 PET/CT for Predicting Outcome in Limited-Stage Small Cell Lung Cancer
A completed clinical trial evaluating CXCR4 PET/CT as a predictor of outcomes in limited-stage small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer [Phase 3]
Phase III trial evaluating maintenance lurbinectedin in combination with atezolizumab versus atezolizumab alone in extensive-stage small-cel…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer [Phase 3]
Phase III open-label study comparing maintenance lurbinectedin plus atezolizumab vs atezolizumab alone in extensive-stage small-cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Detection of Plasma DNA in Non Small Cell and Small Cell Lung Cancer Patients [NA]
A completed clinical trial examined detection of plasma DNA in patients with non-small cell lung cancer and small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Prospective, Single-Arm, Exploratory Study of IBI363 in ES-SCLC Patients After Immunotherapy Progression [Phase 2]
This document reports a Phase 2 prospective, single-arm exploratory study evaluating the investigational drug IBI363 in patients with extens…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating the PLK1 inhibitor Onvansertib in relapsed small cell lung cancer; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial [NA]
Completed clinical trial evaluating a supportive care intervention (ROAR-LCT) for patients with advanced non-small cell lung cancer and smal…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) [Phase 1]
Amgen's Phase 1 study is assessing safety, tolerability, and pharmacokinetics of Tarlatamab in adults with small cell lung cancer, with the …
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating whether adding tiragolumab to atezolizumab plus carboplatin and etoposide improves outcomes in untreated extensive-…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer [Phase 3]
Phase 3 study of atezolizumab plus carboplatin and etoposide with or without tiragolumab in untreated extensive-stage small cell lung cancer…