Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: A Study on the First-line Treatment of Small Cell Lung Cancer With Adebrelimab and Vunakizumab and Chemotherapy [Phase 2]
A Phase 2 trial is evaluating first-line treatment of small cell lung cancer using adebrelimab and vunakizumab in combination with chemother…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
This clinical trial update reports long-term follow-up of participants treated with A2 Biotherapeutics' gene therapy products in solid tumor…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer [NA]
Prospective study evaluating intensity-modulated proton therapy for small cell lung cancer is currently recruiting. The study is sponsored b…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Phase 1 Study of HS-20093 Combinations in Patients With Extensive Stage Small Cell Lung Cancer [Phase 1]
Clinical trial update describing a Phase 1 study of HS-20093 in combination regimens for extensive-stage small cell lung cancer; the study i…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of infusions of iNKT cells and CD8+ T cells in patients with advanced solid tu…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Radiotherapy or Observation of Liver Metastases in Small Cell Lung Cancer [NA]
A clinical trial comparing radiotherapy versus observation for liver metastases in small cell lung cancer; currently recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating MHB088C injection vs physician's choice in relapsed extensive-stage small cell lung cancer is currently recruitin…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: A Multi-omics Sequencing-based Model for Predicting Efficacy and Dynamic Monitoring of Treatment in Small Cell Lung Cancer
A clinical trial is evaluating a multi-omics sequencing-based model to predict treatment efficacy and dynamically monitor response in small …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating dose-escalated adaptive radiotherapy for thoracic disease in small c…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This update covers a completed Phase 1/2 clinical trial evaluating Tinengotinib (TT-00420) as both monotherapy and in combination therapy fo…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: PEI REGIMEN: A Therapeutic Option in Small Cell Lung Cancer? A Monoinstitutional Experience of 46 Consecutive Cases
A monoinstitutional retrospective report of 46 consecutive small cell lung cancer patients treated with the PEI REGIMEN, providing real-worl…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Efficacy and Biomarkers of the Second-line Treatment of Adebelizumab Combined With Irinotecan Liposome in Advanced Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the efficacy and biomarkers of Adebelizumab in combination with liposomal irinotecan as a second-line trea…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Omitting CTV for Primary Tumor in LS-SCLC [Phase 3]
Phase 3 clinical trial update evaluating omitting the clinical target volume (CTV) for the primary tumor in limited-stage small cell lung ca…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Two Schedules of Hyperfractionated Thoracic Radiotherapy in Limited Disease Small Cell Lung Cancer [NA]
This clinical trial update describes two hyperfractionated thoracic radiotherapy schedules for limited-stage small cell lung cancer; the stu…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Prospective Feasibility Pilot Study Evaluating the Value of [68Ga]Ga-PENTIXAFOR PET-CT in Patients With Metastatic Small Cell Lung Cancer (SCLC) at Diagnosis and Disease Progression [EARLY_Phase 1]
An early Phase 1 feasibility trial evaluating 68Ga-PENTIXAFOR PET-CT imaging for CXCR4 targeting in metastatic small cell lung cancer at dia…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors [Phase 1]
A Phase 1 trial from Chipscreen Biosciences assesses safety, pharmacokinetics, and preliminary efficacy of CS231295 in adults with advanced …
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer [Phase 3]
Phase 3 MAVERICK trial S1827 is evaluating whether brain scans alone (without preventive brain radiation) affect lifespan in patients with s…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC [Phase 1, Phase 2]
Status update on ONC-392 showing safety, pharmacokinetics, and preliminary efficacy in monotherapy and in combination with anti-PD-1 across …
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01) [Phase 1, Phase 2]
KL264-01, a Trop2-targeted antibody-drug conjugate, is being studied in a Phase 1/2 trial for advanced unresectable or metastatic solid tumo…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC) [Phase 2]
Phase 2 clinical trial evaluating maintenance durvalumab and olaparib after first-line therapy in HRD-positive extensive-disease small cell …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Combined With Chemotherapy With or Without Anlotinib in Resectable Limited-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 exploratory clinical trial evaluating Benmelstobart with chemotherapy, with or without Anlotinib, in resectable limited-stage small …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC [Phase 1]
Phase I study of α-PD-L1/DLL3 CAR-T therapy in patients with relapsed/refractory small cell lung cancer (extensive stage) is currently recru…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: A Study of SYS6040 for Injection in Patients With Advanced Solid Tumors [Phase 1]
This entry describes a Phase 1 clinical trial of SYS6040 for injection in patients with small cell lung cancer and other advanced solid tumo…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
A clinical trial update describing a study to quantify systemic immunosuppression to personalize cancer therapy and that the trial is curren…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: IN10018 Combination Therapy in Treatment-naïve ES-SCLC [Phase 1, Phase 2]
Clinical trial update for IN10018 combination therapy in treatment-naïve extensive-stage small cell lung cancer. The study is in Phase 1 and…