Small Cell Lung Cancer
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Phase I Trial of CArbonic Anhydrase Inhibition in Combination With Radiochemotherapy or Radioimmunotherapy in Small Cell Lung Carcinoma [Phase 1]
Phase I clinical trial update for an investigational carbonic anhydrase inhibitor in combination with radiochemotherapy or radioimmunotherap…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors [Phase 2]
ClinicalTrials.gov update for QUILT-3.055, a Phase 2 study of combination immunotherapies in patients who previously received immune checkpo…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors [Phase 1, Phase 2]
A first-in-human Phase 1/2 trial of JAB-8263 in adults with advanced tumors is currently recruiting across multiple cancer types including l…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: JAB-2485 Activity in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Jacobio's JAB-2485 is being studied in Phase 1/2 for adults with advanced solid tumors, including breast cancer subtypes and small cell lung…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice
This clinical trial update reports on real-world outcomes and safety of atezolizumab in routine practice. It includes patients with urotheli…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56 [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating PET/CT imaging of small cell lung cancer with the radiotracer 89Zr-DFO-SC16.56, sponsored by Me…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study Evaluating the Efficacy and Safety of ABP1011T Tablets in Patients With Advanced Solid Tumors [Phase 2]
Phase 2 clinical trial update evaluating ABP1011T tablets for small cell lung cancer and other advanced solid tumors; recruitment is ongoing…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Study of ZG006 in Participants With Small Cell Lung Cancer or Neuroendocrine Carcinoma [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial of ZG006 for Small cell lung cancer and neuroendocrine carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Study Comparing ZG006 With Investigator-Selected Chemotherapy in Participants With Relapsed Small Cell Lung Cancer [Phase 3]
A phase 3 study compares ZG006 with investigator-selected chemotherapy in relapsed small cell lung cancer. The trial is currently recruiting…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: ZG006 and ZG005 in Participants With Small Cell Lung Cancer or Neuroendocrine Carcinoma [Phase 1, Phase 2]
This clinical trial update reports that ZG005 and ZG006 are being studied in Phase 1/Phase 2 trials for small cell lung cancer and neuroendo…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Real-World Study of Toripalimab in Extensive-Stage Small Cell Lung Cancer
This entry notes a real-world study of toripalimab for extensive-stage small cell lung cancer, with the study currently not recruiting.
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial) [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial evaluating irinotecan in combination with a CDC2-like kinase inhibitor (the SLICK trial) for small cell l…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC) [Phase 2]
This update describes a Phase 2 study of tarlatamab in relapsed/refractory small cell lung cancer; the trial is currently active but not rec…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update notes a phase 1/phase 2 study evaluating the combination of lurbinectedin with osimertinib in transformed small c…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer [Phase 2]
Phase 2 clinical trial update evaluating nivolumab plus temozolomide in patients with recurrent or refractory small-cell lung cancer or adva…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab [Phase 3]
A Phase 3 trial is evaluating Tarlatamab plus Durvalumab versus Durvalumab alone as first-line therapy for extensive-stage small-cell lung c…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial evaluating ST-001 nanoFenretinide in relapsed or refractory small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma [Phase 1, Phase 2]
Clinical trial update for VMD-928 as a monotherapy and in combination with pembrolizumab to treat TrkA overexpression-driven solid tumors or…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3 [Phase 1]
Phase 1 study evaluating different doses of BI 764532 in DLL3-positive small cell lung cancer and other neuroendocrine tumors; the trial is …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating post-line treatment with teniposide for c-Myc-driven extensive-stage small cell lung cancer; recrui…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Study of GV20-0251 in Participants With Solid Tumor Malignancies [Phase 1, Phase 2]
GV20 Therapeutics is evaluating GV20-0251 in a Phase 1/2 trial for adults with various solid tumors, and the study is currently recruiting. …
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Olvi-Vec Combined With Platinum Plus Etoposide Therapy in Patients With Late Phase SCLC [Phase 1, Phase 2]
A clinical trial update indicates an ongoing Phase 1/Phase 2 study of Olvi-Vec in combination with platinum-based chemotherapy and etoposide…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC [Phase 2]
Phase 2 clinical trial assessing CDK4/6 inhibitors for chemo-refractory, RB wild-type extensive small-cell lung cancer. The study also inclu…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects With Advanced Lung Cancer [Phase 2]
Phase II clinical study to evaluate HLX43 in combination with Serplulimab for advanced lung cancer; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: 7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
A clinical trial evaluating the use of 7T brain MRI to detect micro-brain metastases in small-cell lung cancer patients who decline prophyla…