Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating radiotherapy with durvalumab, and a durvalumab-tremelimumab-olaparib combination, for small cell lung cancer; the t…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1) [Phase 1]
Phase 1 first-in-human study of ML261, an autologous DLL3-targeted CAR T cell therapy, in relapsed/refractory small cell lung cancer and sel…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of durvalumab and lurbinectedin for relapsed or refractory small cell lung cancer; the stu…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial [Phase 3]
This clinical trials entry describes a Phase III randomized trial evaluating dose-escalation radiotherapy for limited-stage small cell lung …
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: DESTINY-PANTUMOUR04
Clinical trial update for the DESTINY-PANTUMOUR04 study sponsored by AstraZeneca, evaluating trastuzumab deruxtecan across multiple cancer t…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study [Phase 2]
Phase 2 PRISM trial uses biomarker tests to guide selection of personalized therapies for extensive-stage small cell lung cancer; currently …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Phase 2 Study of Fingolimod in Lung Cancers [Phase 2]
Phase 2 clinical trial evaluating Fingolimod in non-small cell lung cancer and small-cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection [Phase 2]
Phase 2 trial assessing the imaging tracer 18F-FAPI-74 for cancer detection across multiple indications; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance [NA]
Massachusetts General Hospital reports an update on the Transitions Project, a study to support adults moving from cancer treatment to surve…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Durvalumab as Consolidation for Patients LS-SCLC [Phase 2]
Durvalumab is being studied as consolidation therapy for limited-stage small cell lung cancer in a Phase 2 trial. The study is currently rec…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of Hospital-at-Home for People Receiving Tarlatamab [NA]
This clinical trial update notes that a hospital-at-home study is evaluating care for patients with small cell lung cancer who are receiving…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors [Phase 1]
Phase I study of [225Ac]Ac-ETN029 for DLL3-expressing advanced solid tumors is currently recruiting, sponsored by Novartis Pharmaceuticals.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV [Phase 1]
This is a Phase 1 clinical trial evaluating the combination of cabozantinib (XL184) and nivolumab in patients with various advanced cancers …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors [Phase 1]
Phase 1 clinical trial update for AVA6103 in patients with locally advanced or metastatic selected solid tumors; the study is currently recr…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers [Phase 1, Phase 2]
A Phase 1/2 trial evaluating lurbinectedin in combination with berzosertib (an ATR kinase inhibitor) for small cell cancers and high-grade n…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI Progression [Phase 2]
Phase 2 clinical trial evaluating limertinib in combination with carboplatin and etoposide for EGFR-mutant non-small cell lung cancer with t…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating trilaciclib to prevent myelosuppression in limited-stage small cell lung cancer; status shows not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: SYS6090 Combination Therapy in Advanced Lung Cancer [Phase 1, Phase 2]
Clinical trial update for SYS6090 combination therapy in advanced lung cancer, covering Phase 1 and Phase 2 studies; currently not yet recru…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) [Phase 1, Phase 2]
PMV Pharmaceuticals is evaluating PC14586 in a Phase 1/2 trial for advanced solid tumors harboring the TP53 Y220C mutation. The study is cur…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of Alisertib and Paclitaxel in Patients With Small Cell Lung Cancer (SCLC) [Phase 2]
This update describes a Phase 2 clinical trial evaluating alisertib in combination with paclitaxel for small cell lung cancer, which is curr…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: SCLC Tarlatamab Blood Collection
Duke University is conducting a small-cell lung cancer trial of tarlatamab, which is currently not yet recruiting and involves blood collect…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC [Phase 1, Phase 2]
An early-phase, biomarker-directed trial is evaluating temozolomide in combination with stenoparib for relapsed small cell lung cancer and i…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON) [Phase 3]
Phase 3 trial update (LAGOON) evaluating lurbinectedin as a single agent or with irinotecan compared with topotecan or irinotecan in relapse…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer [Phase 1, Phase 2]
A clinical study to assess the safety and tolerability of BMS-986525 alone and with nivolumab in relapsed/refractory small cell lung cancer,…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SNB-101 for extensive-stage small cell lung cancer is currently recruiting.